Compile Data Set for Download or QSAR
Found 561 with Last Name = 'toma?i?' and Initial = 't'
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50408204(CHEMBL4165664)copy SMILEScopy InChI
Affinity DataKi: <0.0500nMAssay Description:Inhibition of Escherichia coli DNA gyrase BMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Department of Chemistry, Faculty of Medicine, University of Ni?, Bulevar Dr Zorana?in?i?a 81, 18000 Ni?, Serbia.

Curated by ChEMBL
LigandPNGBDBM50320491(2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-METHYL-5-THIAZOLE...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Non-competitive inhibition of human xanthine oxidaseMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Department of Chemistry, Faculty of Medicine, University of Ni?, Bulevar Dr Zorana?in?i?a 81, 18000 Ni?, Serbia.

Curated by ChEMBL
LigandPNGBDBM50267750(CHEMBL1078685)copy SMILEScopy InChI
Affinity DataKi:  5.70nMAssay Description:Competitive inhibition of bovine milk xanthine oxidoreductase assessed as reduction in uric acid formation by spectrophotometric assayMore data for this Ligand-Target Pair
LigandPNGBDBM50226181((3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-...)copy SMILEScopy InChI
Affinity DataIC50: 0.650nMMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50613099(CHEMBL5288212)copy SMILES
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50494811(CHEMBL3094350)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of BRD4 bromodomain 1 (unknown origin) incubated in dark for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3HK1PubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50547859(CHEMBL4752708)copy SMILES
Affinity DataIC50: 4.80nMAssay Description:Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8JGGPubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Department of Chemistry, Faculty of Medicine, University of Ni?, Bulevar Dr Zorana?in?i?a 81, 18000 Ni?, Serbia.

Curated by ChEMBL
LigandPNGBDBM50098068(1-[3-CYANO-4-(NEOPENTYLOXY)PHENYL]-1H-PYRAZOLE-4-C...)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Inhibition of bovine milk xanthine-oxygen reductase using xanthine as substrate by spectrophotometric assayMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50249798(CHEMBL4795890)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMAssay Description:Evaluated for the percent binding affinity against H1 receptor by an H1 histamine-mediated bronchospasmMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3HK1PubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Department of Chemistry, Faculty of Medicine, University of Ni?, Bulevar Dr Zorana?in?i?a 81, 18000 Ni?, Serbia.

Curated by ChEMBL
LigandPNGBDBM50098065(1-(3-Cyano-4-isobutoxy-phenyl)-1H-pyrazole-4-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 7.10nMAssay Description:Inhibition of bovine milk xanthine-oxygen reductase using xanthine as substrate by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD71XPPubMed
LigandPNGBDBM50613099(CHEMBL5288212)copy SMILES
Ligand InfoPC cidPC sidPDB
In DepthDetails
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50547862(CHEMBL4792402)copy SMILES
Affinity DataIC50: 9.5nMAssay Description:Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8JGGPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50249796(CHEMBL4752072)copy SMILEScopy InChI
Affinity DataIC50: 9.90nMAssay Description:Evaluated for the percent binding affinity against H1 receptor by an H1 histamine-mediated bronchospasmMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3HK1PubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50568735(CHEMBL4870243)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50568728(CHEMBL4850565)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50568713(CHEMBL4851285)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)TBA
LigandPNGBDBM50568732(CHEMBL4871682)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)TBA
LigandPNGBDBM50568731(CHEMBL4873249)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)TBA
LigandPNGBDBM50568730(CHEMBL4878712)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)TBA
LigandPNGBDBM50568728(CHEMBL4850565)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)TBA
LigandPNGBDBM50568729(CHEMBL4868482)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
LigandPNGBDBM50613099(CHEMBL5288212)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
LigandPNGBDBM50568726(CHEMBL4854181)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
LigandPNGBDBM50613107(CHEMBL5267594)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50613105(CHEMBL5271811)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50613104(CHEMBL5268463)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50613103(CHEMBL5269847)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50613100(CHEMBL5275604)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50613099(CHEMBL5288212)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50568709(CHEMBL4877458)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50568717(CHEMBL4874918)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50568718(CHEMBL4857022)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50568720(CHEMBL4862321)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50568722(CHEMBL4847190)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50568723(CHEMBL4847090)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50568724(CHEMBL4850231)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50568726(CHEMBL4854181)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50568727(CHEMBL4867874)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50568729(CHEMBL4868482)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50568730(CHEMBL4878712)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50568731(CHEMBL4873249)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50568732(CHEMBL4871682)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50568733(CHEMBL4858015)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50568734(CHEMBL4876030)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50568737(CHEMBL4852505)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50568738(CHEMBL4868407)copy SMILES
Affinity DataIC50: 11nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50568708(CHEMBL4863169)copy SMILES
Affinity DataIC50: 11nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))TBA
LigandPNGBDBM50568714(CHEMBL4857352)copy SMILES
Affinity DataIC50: 12nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in relaxation of supercoiled pNO1 DNA measured after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60STNPubMed
TargetDNA gyrase subunit B(Escherichia coli (strain K12))
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50408191(CHEMBL4163243)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of Escherichia coli C-terminal His6-tagged DNA gyrase B expressed in Escherichia coli BL21(DE3) preincubated for 10 mins followed by ATP a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4M9NPubMed
LigandPNGBDBM50613106(CHEMBL5276709)copy SMILES
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
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