Compile Data Set for Download or QSAR
Found 145 with Last Name = 'tsujita' and Initial = 't'
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244370((7R,9S)-7-((4-(2,6-dichlorophenyl)piperidin-1-yl)m...)copy SMILEScopy InChI
Affinity DataKi:  0.470nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244371((7R,9S)-7-((4-(2-chlorophenyl)piperidin-1-yl)methy...)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50243726((7R,9S)-7-(((3S,4R)-3-methyl-4-o-tolylpiperidin-1-...)copy SMILEScopy InChI
Affinity DataKi:  3.5nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50243729((7R,9S)-7-(((3S,4S)-4-(4-fluoro-2-methylphenyl)-3-...)copy SMILEScopy InChI
Affinity DataKi:  3.70nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50243727((7R,9S)-7-(((3S,4R)-3-(hydroxymethyl)-4-o-tolylpip...)copy SMILEScopy InChI
Affinity DataKi:  4.30nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50243730((7R,9S)-7-(((3R,4R)-4-(2-chloro-4-fluorophenyl)-3-...)copy SMILEScopy InChI
Affinity DataKi:  4.40nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244297(CHEMBL513585 | cis-1-methyl-7-((4-o-tolylpiperidin...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50243728((7R,9S)-7-(((3S,4S)-3-hydroxy-4-o-tolylpiperidin-1...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50243887((-)-(3R,4R)-4-(2-Chloro-4-fluorophenyl)-3-hydroxy-...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244336((6R,8S)-6-((4-o-tolylpiperidin-1-yl)methyl)-5,6,7,...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244334((7R)-9-methyl-7-((4-o-tolylpiperidin-1-yl)methyl)-...)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244334((7R)-9-methyl-7-((4-o-tolylpiperidin-1-yl)methyl)-...)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244295((-)-7-((4-o-tolylpiperidin-1-yl)methyl)-6,7,8,9-te...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244295((-)-7-((4-o-tolylpiperidin-1-yl)methyl)-6,7,8,9-te...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244372((7R,9S)-7-((4-o-tolylpiperazin-1-yl)methyl)-6,7,8,...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50243886((6R,8S)-6-(((3R,4R)-4-(4-fluoro-2-methylphenyl)-3-...)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244335((3R)-3-{[4-(2-methylphenyl)piperidin-1-yl]methyl}-...)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244373((7R,9S)-7-((4-phenylpiperidin-1-yl)methyl)-6,7,8,9...)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244333((R)-7-((4-o-tolylpiperidin-1-yl)methyl)-5,6,7,8-te...)copy SMILEScopy InChI
Affinity DataKi:  49nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50243797((6R,8S)-6-(((3R,4R)-3-hydroxy-4-o-tolylpiperidin-1...)copy SMILEScopy InChI
Affinity DataKi:  51nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244374((7R,9S)-7-((4-methyl-4-phenylpiperidin-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataKi:  58nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244296((-)-(7R,9S)-7-{[4-(2-Methylphenyl)piperidin-1-yl]m...)copy SMILEScopy InChI
Affinity DataKi:  280nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM29986(arylpyrazole, 31)copy SMILEScopy InChI
Affinity DataIC50: 0.310nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9958FPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM29986(arylpyrazole, 31)copy SMILEScopy InChI
Affinity DataIC50: 0.520nM EC50:  0.310nMAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289145GPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM29986(arylpyrazole, 31)copy SMILEScopy InChI
Affinity DataIC50: 0.520nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9958FPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296581((1S,3R)-N-((1-ethyl-5-(5-fluoro-6-methylpyridin-3-...)copy SMILEScopy InChI
Affinity DataIC50: 0.610nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9958FPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296580((1S,3R)-3-fluoro-N-((5-(5-fluoro-6-methylpyridin-3...)copy SMILEScopy InChI
Affinity DataIC50: 0.610nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9958FPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296580((1S,3R)-3-fluoro-N-((5-(5-fluoro-6-methylpyridin-3...)copy SMILEScopy InChI
Affinity DataIC50: 0.920nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9958FPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296590((1S,3R)-N-((5-(3,5-difluorophenyl)-4-(methoxymethy...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9958FPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM29985(arylpyrazole, 30)copy SMILEScopy InChI
Affinity DataIC50: 1.10nM EC50:  1.20nMAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289145GPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296590((1S,3R)-N-((5-(3,5-difluorophenyl)-4-(methoxymethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9958FPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50244370((7R,9S)-7-((4-(2,6-dichlorophenyl)piperidin-1-yl)m...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296581((1S,3R)-N-((1-ethyl-5-(5-fluoro-6-methylpyridin-3-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9958FPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296582((1S,3R)-3-fluoro-N-((5-(5-fluoro-6-methylpyridin-3...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9958FPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296586((1S,3R)-N-((5-(3,5-difluorophenyl)-1,4-dimethyl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at ORL1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9958FPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296589((1S,3R)-N-((4-chloro-5-(3,5-difluorophenyl)-1-meth...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at ORL1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9958FPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM29983(arylpyrazole, 28)copy SMILEScopy InChI
Affinity DataIC50: 2.5nM EC50:  1nMAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289145GPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296586((1S,3R)-N-((5-(3,5-difluorophenyl)-1,4-dimethyl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9958FPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM29974(arylpyrazole, 19)copy SMILEScopy InChI
Affinity DataIC50: 4nM EC50:  4.70nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289145GPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296582((1S,3R)-3-fluoro-N-((5-(5-fluoro-6-methylpyridin-3...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9958FPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50243729((7R,9S)-7-(((3S,4S)-4-(4-fluoro-2-methylphenyl)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296579(3-[5-(3,5-difluorophenyl)-3-({[(1S,3R)-3-fluorocyc...)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9958FPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50243730((7R,9S)-7-(((3R,4R)-4-(2-chloro-4-fluorophenyl)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human ORL1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50243726((7R,9S)-7-(((3S,4R)-3-methyl-4-o-tolylpiperidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Antagonist activity at human ORL1 expressed in CHO cells assessed as effect on nociceptin-induced GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296584((1S,3R)-N-((5-(3,4-difluorophenyl)-1,4-dimethyl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 6.40nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9958FPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296584((1S,3R)-N-((5-(3,4-difluorophenyl)-1,4-dimethyl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9958FPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50243727((7R,9S)-7-(((3S,4R)-3-(hydroxymethyl)-4-o-tolylpip...)copy SMILEScopy InChI
Affinity DataIC50: 7.30nMAssay Description:Antagonist activity at human ORL1 expressed in CHO cells assessed as effect on nociceptin-induced GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5FTWPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296583((1S,3R)-3-fluoro-N-((5-(5-fluoro-6-methylpyridin-3...)copy SMILEScopy InChI
Affinity DataIC50: 7.80nMAssay Description:Antagonist activity at ORL1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9958FPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50296579(3-[5-(3,5-difluorophenyl)-3-({[(1S,3R)-3-fluorocyc...)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9958FPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM29981(arylpyrazole, 26)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q289145GPubMed
Displayed 1 to 50 (of 145 total ) | Next | Last >>
Jump to: