Compile Data Set for Download or QSAR
Found 36 with Last Name = 'tsuruo' and Initial = 't'
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Novartis Takarazuka Research Institute

Curated by ChEMBL
LigandPNGBDBM50390978(VALSPODAR)copy SMILEScopy InChI
Affinity DataKi:  134nMAssay Description:TP_TRANSPORTER: inhibition of ATPase activity (Verapamil) in P-gp-MRP-16-Protein A complexMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055FWPubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Novartis Takarazuka Research Institute

Curated by ChEMBL
LigandPNGBDBM50485592(CHEMBL350445)copy SMILEScopy InChI
Affinity DataKi:  400nMAssay Description:TP_TRANSPORTER: inhibition of Taxol transepithelial transport (basal to apical) in Caco-2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2KM1PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288232(2-[2-(carboxymethoxy)-4-(2-{4H,5H,6H,7H-thieno[2,3...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of Vitronectin binding to GPIIb/IIIIa Vitronectin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288220((2-Carboxymethoxy-5-{2-[(4,5,6,7-tetrahydro-thieno...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Biotinylated fibrinogen binding to alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288220((2-Carboxymethoxy-5-{2-[(4,5,6,7-tetrahydro-thieno...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Inhibition of biotinylated fibrinogen binding to alphaIIb-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288227((2-Carboxymethoxy-5-{2-[(5,6,7,8-tetrahydro-4H-thi...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of vWF binding to alphaIIb-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288218((2-Carboxymethoxy-5-{2-[(5,6,7,8-tetrahydro-4H-thi...)copy SMILEScopy InChI
Affinity DataIC50: 8.70nMAssay Description:Inhibition of biotinylated fibrinogen binding to alphaIIb-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288230((4-Carboxymethoxy-6-{2-[(4,5,6,7-tetrahydro-thieno...)copy SMILEScopy InChI
Affinity DataIC50: 9.80nMAssay Description:Biotinylated fibrinogen binding to alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288229((2-Carboxymethoxy-5-{2-[(3-methyl-4,5,6,7-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Biotinylated fibrinogen binding to alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288220((2-Carboxymethoxy-5-{2-[(4,5,6,7-tetrahydro-thieno...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of biotinylated fibrinogen binding to alphaIIb-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288225((4-{2-[(4,5,6,7-Tetrahydro-thieno[3,2-c]pyridine-2...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Biotinylated fibrinogen binding to alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288231(CHEMBL89257 | {2-Carboxymethoxy-5-[2-(3-piperidin-...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Biotinylated fibrinogen binding to alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288223(2-{4-[2-({3-benzyl-4H,5H,6H,7H-thieno[3,2-c]pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Biotinylated fibrinogen binding to alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50107402((S)-2-[2-((S)-2-Amino-5-carbamimidoyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Biotinylated fibrinogen binding to alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288224(3-(4-{2-[(4,5,6,7-Tetrahydro-thieno[3,2-c]pyridine...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of vWF binding to GPIIb/IIIIa receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288234((5-Carboxymethoxy-2-{2-[(4,5,6,7-tetrahydro-thieno...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Biotinylated fibrinogen binding to alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288219((2-Carboxymethoxy-4-{2-[(5,6-dihydro-4H-thieno[2,3...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of Vitronectin binding to GPIIb/IIIIa Vitronectin receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288228((6-{2-[(4,5,6,7-Tetrahydro-thieno[3,2-c]pyridine-2...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Biotinylated fibrinogen binding to alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288226(CHEMBL313369 | {2-Carboxymethoxy-5-[2-(4-piperidin...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Biotinylated fibrinogen binding to alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288233(CHEMBL89680 | {2-Carboxymethoxy-5-[2-(2-piperidin-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Biotinylated fibrinogen binding to alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Japanese Foundation for Cancer Research

Curated by ChEMBL
LigandPNGBDBM20625(4-[(3E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol | ...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:TP_TRANSPORTER: drug resistance(Mitoxantrone) in BCRP-expressing K562 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J104FDPubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Japanese Foundation for Cancer Research

Curated by ChEMBL
LigandPNGBDBM20625(4-[(3E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol | ...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:TP_TRANSPORTER: drug resistance(SN-38) in BCRP-expressing K562 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J104FDPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288221((4-{2-[(4-Aminomethyl-cyclohexanecarbonyl)-amino]-...)copy SMILEScopy InChI
Affinity DataIC50: 730nMAssay Description:Inhibition of biotinylated fibrinogen binding to alphaIIb-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288235((2-Carboxymethoxy-4-{2-[(piperidine-4-carbonyl)-am...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Biotinylated fibrinogen binding to alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288222((3-Carboxymethoxy-5-{2-[(4,5,6,7-tetrahydro-thieno...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Biotinylated fibrinogen binding to alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50107402((S)-2-[2-((S)-2-Amino-5-carbamimidoyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Biotinylated fibrinogen binding to alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Japanese Foundation for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50420175(CHEMBL2074917)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:TP_TRANSPORTER: drug resistance(Mitoxantrone) in BCRP-expressing K562 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J104FDPubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Japanese Foundation for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50420176(CHEMBL2074984)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:TP_TRANSPORTER: drug resistance(SN-38) in BCRP-expressing K562 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J104FDPubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Japanese Foundation for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50420175(CHEMBL2074917)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:TP_TRANSPORTER: drug resistance(SN-38) in BCRP-expressing K562 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J104FDPubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Japanese Foundation for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50420176(CHEMBL2074984)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:TP_TRANSPORTER: drug resistance(Mitoxantrone) in BCRP-expressing K562 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J104FDPubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Japanese Foundation for Cancer Research

Curated by ChEMBL
LigandPNGBDBM17289((1S,10R,11S,15S)-5-hydroxy-15-methyltetracyclo[8.7...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:TP_TRANSPORTER: drug resistance(Mitoxantrone) in BCRP-expressing K562 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J104FDPubMedDrugBank
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Japanese Foundation for Cancer Research

Curated by ChEMBL
LigandPNGBDBM40489(DIETHYLSTILBESTROL DIPROPIONATE | MLS000028439 | S...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:TP_TRANSPORTER: drug resistance(Mitoxantrone) in BCRP-expressing K562 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J104FDPubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Japanese Foundation for Cancer Research

Curated by ChEMBL
LigandPNGBDBM40489(DIETHYLSTILBESTROL DIPROPIONATE | MLS000028439 | S...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:TP_TRANSPORTER: drug resistance(SN-38) in BCRP-expressing K562 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J104FDPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50107402((S)-2-[2-((S)-2-Amino-5-carbamimidoyl-pentanoylami...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Biotinylated fibrinogen binding to alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Japanese Foundation for Cancer Research

Curated by ChEMBL
LigandPNGBDBM17289((1S,10R,11S,15S)-5-hydroxy-15-methyltetracyclo[8.7...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:TP_TRANSPORTER: drug resistance(SN-38) in BCRP-expressing K562 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J104FDPubMedDrugBank
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288220((2-Carboxymethoxy-5-{2-[(4,5,6,7-tetrahydro-thieno...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Biotinylated fibrinogen binding to alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W76