Compile Data Set for Download or QSAR
Found 27 with Last Name = 'kwan' and Initial = 'ta'
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24923(5-(carbamoylamino)-3-[(5R)-6,7,8,9-tetrahydro-5H-b...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24922(5-(carbamoylamino)-3-{6,7,8,9-tetrahydro-5H-benzo[...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24899(3-{[1-(4-chlorophenyl)ethyl]sulfanyl}-5-[(methylca...)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24901(3-{[(1R)-1-(4-chlorophenyl)propyl]sulfanyl}-5-[(me...)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24898(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-[(methylcar...)copy SMILEScopy InChI
Affinity DataIC50: 7nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24919(3-[(5-chloro-2,3-dihydro-1H-inden-1-yl)sulfanyl]-5...)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24900(3-{[1-(4-chlorophenyl)propyl]sulfanyl}-5-[(methylc...)copy SMILEScopy InChI
Affinity DataIC50: 9nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24918(5-(carbamoylamino)-3-[(5-chloro-2,3-dihydro-1H-ind...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24903(3-{[1-(4-chlorophenyl)-2-methylpropyl]sulfanyl}-5-...)copy SMILEScopy InChI
Affinity DataIC50: 16nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24910(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-(pyridin-3-...)copy SMILEScopy InChI
Affinity DataIC50: 19nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24914(3-{[(2-chlorophenyl)methyl]sulfanyl}-5-(pyridin-4-...)copy SMILEScopy InChI
Affinity DataIC50: 28nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24911(3-{[1-(4-chlorophenyl)ethyl]sulfanyl}-5-(pyridin-3...)copy SMILEScopy InChI
Affinity DataIC50: 29nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24909(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-(pyridin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 33nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24904(3-{[1-(4-chlorophenyl)butyl]sulfanyl}-5-[(methylca...)copy SMILEScopy InChI
Affinity DataIC50: 35nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24913(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-(pyridin-4-...)copy SMILEScopy InChI
Affinity DataIC50: 45nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24915(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-(pyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 47nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24902(3-{[(1S)-1-(4-chlorophenyl)propyl]sulfanyl}-5-[(me...)copy SMILEScopy InChI
Affinity DataIC50: 52nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24917(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-[(6-oxo-1,6...)copy SMILEScopy InChI
Affinity DataIC50: 84nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24924(5-(carbamoylamino)-3-[(5S)-6,7,8,9-tetrahydro-5H-b...)copy SMILEScopy InChI
Affinity DataIC50: 91nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24920(5-(carbamoylamino)-3-(1,2,3,4-tetrahydronaphthalen...)copy SMILEScopy InChI
Affinity DataIC50: 105nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24905(3-{[1-(4-chlorophenyl)-2,2,2-trifluoroethyl]sulfan...)copy SMILEScopy InChI
Affinity DataIC50: 110nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24921(5-[(methylcarbamoyl)amino]-3-(1,2,3,4-tetrahydrona...)copy SMILEScopy InChI
Affinity DataIC50: 111nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24916(3-{[(4-chlorophenyl)methyl]sulfanyl}-5-[(6-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 179nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24912(3-[(cyclohexylmethyl)sulfanyl]-5-(pyridin-3-ylamin...)copy SMILEScopy InChI
Affinity DataIC50: 610nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24906(3-{[(4-chlorophenyl)(phenyl)methyl]sulfanyl}-5-[(m...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24908(5-amino-3-{[(4-chlorophenyl)methyl]sulfanyl}-1,2-t...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Pfizer

LigandPNGBDBM24907(1-(3-{[(4-chlorophenyl)methyl]sulfanyl}-4-cyano-1,...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMpH: 7.4 T: 2°CAssay Description:The kinase domain of the human TrkA receptor in phosphorylation buffer with 0.5 uM ATP is incubated in plates coated with PGT substrate. Compounds ar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1VH5PubMed