Found 79 with Last Name = 'bach' and Initial = 'tb' TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Binding affinity to alpha4beta2 (unknown origin)More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Binding affinity to alpha4beta2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.190nMAssay Description:Antagonist activity at rat GluK1 receptor expressed in Xenopus oocytes by two-electrode voltage-clamp at membrane potential -60 to -80 mV electrophys...More data for this Ligand-Target Pair
Affinity DataIC50: 0.280nMAssay Description:Antagonist activity at rat GluK1 receptor expressed in Xenopus oocytes by two-electrode voltage-clamp at membrane potential -60 to -80 mV electrophys...More data for this Ligand-Target Pair
Affinity DataIC50: 0.330nMAssay Description:Antagonist activity at rat GluK1 receptor expressed in Xenopus oocytes at membrane potential -60 mV by two-electrode voltage-clamp electrophysiology ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.820nMAssay Description:Antagonist activity at rat GluK1 receptor expressed in Xenopus oocytes at membrane potential -60 mV by two-electrode voltage-clamp electrophysiology ...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Antagonist activity at rat GluK1 receptor expressed in Xenopus oocytes at membrane potential -60 mV by two-electrode voltage-clamp electrophysiology ...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Antagonist activity at rat GluA1 receptor expressed in Xenopus oocytes at membrane potential -60 mV by two-electrode voltage-clamp electrophysiology ...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Antagonist activity at rat GluA1 receptor expressed in Xenopus oocytes at membrane potential -60 mV by two-electrode voltage-clamp electrophysiology ...More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...More data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...More data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...More data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Antagonist activity at rat GluA1 receptor expressed in Xenopus oocytes at membrane potential -60 mV by two-electrode voltage-clamp electrophysiology ...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Inhibition of rat GluN1/2A expressed in xenopus laevis oocytes assessed as inhibition of glycine-evoked current at membrane potential of -60 mV by vo...More data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Inhibition of rat GluA1 expressed in xenopus laevis oocytes assessed as inhibition of glutamate-evoked current at membrane potential of -60 mV by vol...More data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...More data for this Ligand-Target Pair
Affinity DataIC50: 77nMAssay Description:Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...More data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...More data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 81nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...More data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...More data for this Ligand-Target Pair
Affinity DataIC50: 94nMAssay Description:Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...More data for this Ligand-Target Pair
Affinity DataIC50: 96nMAssay Description:Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 103nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...More data for this Ligand-Target Pair
Affinity DataIC50: 118nMAssay Description:Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 122nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
Affinity DataIC50: 124nMAssay Description:Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...More data for this Ligand-Target Pair
Affinity DataIC50: 135nMAssay Description:Antagonist activity at rat GluA1 receptor expressed in Xenopus oocytes at membrane potential -60 mV by two-electrode voltage-clamp electrophysiology ...More data for this Ligand-Target Pair
Affinity DataIC50: 137nMAssay Description:Antagonist activity at rat GluA1 receptor expressed in Xenopus oocytes at membrane potential -60 mV by two-electrode voltage-clamp electrophysiology ...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2A(Rattus norvegicus (Rat))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Antagonist activity at rat glutamate N1/2A receptor expressed in Xenopus oocytes at membrane potential -60 mV by two-electrode voltage-clamp electrop...More data for this Ligand-Target Pair
Affinity DataIC50: 164nMAssay Description:Antagonist activity at rat GluK1 receptor expressed in Xenopus oocytes at membrane potential -60 mV by two-electrode voltage-clamp electrophysiology ...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
University of Copenhagen
Curated by ChEMBL
University of Copenhagen
Curated by ChEMBL
Affinity DataIC50: 165nMAssay Description:Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...More data for this Ligand-Target Pair
Affinity DataIC50: 167nMAssay Description:Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...More data for this Ligand-Target Pair
Affinity DataIC50: 171nMAssay Description:Inhibition of rat GluA1 receptor flip form expressed in Xenopus laevis oocyte assessed as glutamate-induced current at holding potentials from -80 to...More data for this Ligand-Target Pair
