Compile Data Set for Download or QSAR
Found 45 with Last Name = 'roethka' and Initial = 'tj'
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50228676((S)-2-(5-chlorothiophen-2-yl)-N-(1-(4-(2-((dimethy...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94NNPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306153((S)-2-(5-chlorothiophen-2-yl)-N-(1-(3-fluoro-2'-(m...)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94NNPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50338686((R/S)-3-chloro-N-((3S)-1-(1-(methylamino)-2,3-dihy...)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052WGPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306146((E)-2-(5-CHLOROTHIOPHEN-2-YL)-N-[(3S)-1-{4-[(1S)-1...)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306143(6-chloro-N-((S)-1-(4-((S)-1-(dimethylamino)ethyl)-...)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94NNPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306138(CHEMBL604887 | N-((3S)-1-(4-(1-(azetidin-1-yl)ethy...)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94NNPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306142(6-chloro-N-((3S)-1-(4-(1-(ethyl(methyl)amino)ethyl...)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94NNPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50338689((R/S)-3-chloro-N-((3S)-1-(1-(dimethylamino)-2,3-di...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052WGPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306140(6-chloro-N-((3S)-1-(2-fluoro-4-(1-(isopropylamino)...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94NNPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306146((E)-2-(5-CHLOROTHIOPHEN-2-YL)-N-[(3S)-1-{4-[(1S)-1...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306148((S)-4-(3-(2-(5-chlorothiophen-2-yl)vinylsulfonamid...)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306147((E)-2-(5-CHLOROTHIOPHEN-2-YL)-N-[(3S)-1-{4-[(1R)-1...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306144(6-chloro-N-((S)-1-(4-((R)-1-(dimethylamino)ethyl)-...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94NNPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306143(6-chloro-N-((S)-1-(4-((S)-1-(dimethylamino)ethyl)-...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94NNPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306141(6-chloro-N-((3S)-1-(4-(1-(ethylamino)ethyl)-2-fluo...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94NNPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306137(6-chloro-N-((3S)-1-(2-fluoro-4-(1-(pyrrolidin-1-yl...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94NNPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306136(6-chloro-N-((3S)-1-(2-fluoro-4-(1-(piperidin-1-yl)...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94NNPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306134(6-chloro-N-((S)-1-(2-fluoro-4-((S)-1-(methylamino)...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94NNPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306134(6-chloro-N-((S)-1-(2-fluoro-4-((S)-1-(methylamino)...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052WGPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50338691(6-CHLORO-N-[(3S)-1-[(1S)-1-DIMETHYLAMINO-2,3-DIHYD...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50338677(6-CHLORO-N-((3S)-2-OXO-1-{4-[(2S)-2-PYRROLIDINYL]P...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50338682((R/S)-3-chloro-N-((3S)-1-(2-fluoro-4-(pyrrolidin-2...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052WGPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50338678(6-CHLORO-N-((3S)-2-OXO-1-{4-[(2R)-2--PYRROLIDINYL]...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50338690(6-CHLORO-N-{(3S)-1-[(1S)-1-(DIMETHYLAMINO)-2,3-DIH...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50338680((E)-2-(5-chlorothiophen-2-yl)-N-((S)-1-(2-fluoro-4...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052WGPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM17643((E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[(2S)-1-(m...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM17643((E)-2-(5-chlorothiophen-2-yl)-N-[(3S)-1-[(2S)-1-(m...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50338692((R/S)-(E)-2-(5-chlorothiophen-2-yl)-N-((3S)-1-(1-(...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052WGPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50338688((R/S)-(E)-2-(5-chlorothiophen-2-yl)-N-((3S)-1-(1-(...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052WGPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50338677(6-CHLORO-N-((3S)-2-OXO-1-{4-[(2S)-2-PYRROLIDINYL]P...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306135(6-chloro-N-((S)-1-(2-fluoro-4-((R)-1-(methylamino)...)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94NNPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50338679((E)-2-(5-chlorothiophen-2-yl)-N-((S)-1-(2-fluoro-4...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052WGPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50338685((R/S)-N-((3S)-1-(1-amino-2,3-dihydro-1H-inden-5-yl...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052WGPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306145(6-chloro-N-((3S)-1-(4-(1-(dimethylamino)ethyl)-2-f...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94NNPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50338687((R/S)-6-chloro-N-((3S)-1-(1-(methylamino)-2,3-dihy...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052WGPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306139(6-chloro-N-((3S)-1-(2-fluoro-4-(1-(isopropyl(methy...)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94NNPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306150((S)-4-(3-(2-(5-chlorothiophen-2-yl)vinylsulfonamid...)copy SMILEScopy InChI
Affinity DataKi:  5.10nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94NNPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50338683((R/S)-6-chloro-N-((3S)-1-(2-fluoro-4-(1-methylpyrr...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052WGPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50338679((E)-2-(5-chlorothiophen-2-yl)-N-((S)-1-(2-fluoro-4...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052WGPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306151((S)-N-(1-(4-acetyl-2-fluorophenyl)-2-oxopyrrolidin...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94NNPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306152((S)-2-(5-chlorothiophen-2-yl)-N-(1-(2-fluoro-4-(pr...)copy SMILEScopy InChI
Affinity DataKi:  6.20nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94NNPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50338690(6-CHLORO-N-{(3S)-1-[(1S)-1-(DIMETHYLAMINO)-2,3-DIH...)copy SMILEScopy InChI
Affinity DataKi:  9nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50338684((R/S)-(E)-2-(5-chlorothiophen-2-yl)-N-((3S)-1-(2-f...)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052WGPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50306149((S)-4-(3-(2-(5-chlorothiophen-2-yl)vinylsulfonamid...)copy SMILEScopy InChI
Affinity DataKi:  35nMAssay Description:Inhibition of human factor 10a by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94NNPubMed
TargetCoagulation factor X(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50338681((R/S)-N-((3S)-1-(2-fluoro-4-(pyrrolidin-2-yl)pheny...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Inhibition of factor 10a activity measured using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28052WGPubMed