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Found 358 with Last Name = 'shipley' and Initial = 'tj'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50413296(CHEMBL473764)copy SMILEScopy InChI
Affinity DataIC50: 0.316nMAssay Description:Inhibition of human recombinant PDE4B by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2J0JPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50413297(CHEMBL473560)copy SMILEScopy InChI
Affinity DataIC50: 0.398nMAssay Description:Inhibition of human recombinant PDE4B by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2J0JPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM14774(3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl...)copy SMILEScopy InChI
Affinity DataIC50: 0.398nMAssay Description:Inhibition of human recombinant PDE4B by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50413291(CHEMBL515240)copy SMILEScopy InChI
Affinity DataIC50: 1.58nMAssay Description:Inhibition of human recombinant PDE4B by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2J0JPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50535083(CHEMBL4460676)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8BT3PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50413286(CHEMBL517766)copy SMILEScopy InChI
Affinity DataIC50: 2.51nMAssay Description:Inhibition of human recombinant PDE4B by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2J0JPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50254466(5-amino-N-(2-((2,6-dichloro-N-ethylbenzamido)methy...)copy SMILEScopy InChI
Affinity DataIC50: 3.16nMAssay Description:Displacement of fluorescent labelled Dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50413298(CHEMBL462150)copy SMILEScopy InChI
Affinity DataIC50: 3.98nMAssay Description:Inhibition of human recombinant PDE4B by scintillation proximity assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50535084(CHEMBL3546703)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8BT3PubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50535112(CHEMBL4439328)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8BT3PubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50419265(CHEMBL1835069)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD12ZWPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50535097(CHEMBL4561098)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8BT3PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50413306(CHEMBL515098)copy SMILEScopy InChI
Affinity DataIC50: 5.01nMAssay Description:Inhibition of human recombinant PDE4B by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2J0JPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50396073(CHEMBL1235110)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50535093(CHEMBL4472827)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8BT3PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50413288(CHEMBL517590)copy SMILEScopy InChI
Affinity DataIC50: 6.31nMAssay Description:Inhibition of human recombinant PDE4B by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2J0JPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50412612(CHEMBL518451)copy SMILEScopy InChI
Affinity DataIC50: 6.31nMAssay Description:Displacement of fluorescent labelled Dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5V79PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50412614(CHEMBL465919)copy SMILEScopy InChI
Affinity DataIC50: 6.31nMAssay Description:Displacement of fluorescent labelled Dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5V79PubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50535107(CHEMBL4468047)copy SMILEScopy InChI
Affinity DataIC50: 7.90nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8BT3PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50412609(CHEMBL520750)copy SMILEScopy InChI
Affinity DataIC50: 7.94nMAssay Description:Displacement of fluorescent labelled Dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5V79PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50254513(5-amino-N-(2-((N-ethyl-2,6-difluorobenzamido)methy...)copy SMILEScopy InChI
Affinity DataIC50: 7.94nMAssay Description:Displacement of fluorescent labelled Dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5V79PubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50419258(CHEMBL1835070)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD12ZWPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM19190((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMAssay Description:Displacement of fluorescent labelled Dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5V79PubMedDrugBank
TargetGlucocorticoid receptor(Homo sapiens (Human))
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50412606(CHEMBL462282)copy SMILEScopy InChI
Affinity DataIC50: 12.6nMAssay Description:Displacement of fluorescent labelled Dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5V79PubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50419256(CHEMBL1835065 | US9579320, Example 302)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD12ZWPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50412608(CHEMBL519947)copy SMILEScopy InChI
Affinity DataIC50: 15.8nMAssay Description:Displacement of fluorescent labelled Dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5V79PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50413299(CHEMBL463417)copy SMILEScopy InChI
Affinity DataIC50: 15.8nMAssay Description:Inhibition of human recombinant PDE4B by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2J0JPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50254760(5-amino-N-(2-((2,6-difluoro-N-(2-hydroxyethyl)benz...)copy SMILEScopy InChI
Affinity DataIC50: 15.8nMAssay Description:Displacement of fluorescent labelled Dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5V79PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50412616(CHEMBL465927)copy SMILEScopy InChI
Affinity DataIC50: 15.8nMAssay Description:Displacement of fluorescent labelled Dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5V79PubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50535089(CHEMBL4528289)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMitogen-activated protein kinase 1/3(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50396073(CHEMBL1235110)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of Erk1/2 phosphorylation expressed in ramos cells after 30 mins by MSD assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD12ZWPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50254759((+/-)-5-amino-N-(2-((2,6-difluoro-N-(2-fluoroethyl...)copy SMILEScopy InChI
Affinity DataIC50: 19.9nMAssay Description:Displacement of fluorescent labelled Dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5V79PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50412611(CHEMBL479431)copy SMILEScopy InChI
Affinity DataIC50: 19.9nMAssay Description:Displacement of fluorescent labelled Dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5V79PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50413285(CHEMBL463418)copy SMILEScopy InChI
Affinity DataIC50: 19.9nMAssay Description:Inhibition of human recombinant PDE4B by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2J0JPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50535088(CHEMBL4584789)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8BT3PubMed
TargetMitogen-activated protein kinase 1/3(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50419256(CHEMBL1835065 | US9579320, Example 302)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of Erk1/2 phosphorylation expressed in ramos cells after 30 mins by MSD assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD12ZWPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50535105(CHEMBL4455268)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8BT3PubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50535118(CHEMBL4460283)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8BT3PubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50535114(CHEMBL4583779)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8BT3PubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50535102(CHEMBL4570588)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8BT3PubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50419263(CHEMBL1835057)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD12ZWPubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50413301(CHEMBL461111)copy SMILEScopy InChI
Affinity DataIC50: 31.6nMAssay Description:Inhibition of human recombinant PDE4B by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2J0JPubMed
TargetAurora kinase B(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50535114(CHEMBL4583779)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of N-terminal-6His-tagged full length human Aurora B expressed in baculovirus using 5FAM-PKA-tide as substrate after 120 mins by fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8BT3PubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50535087(CHEMBL4458845)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8BT3PubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50419247(CHEMBL1835071 | US8470835, 1)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50535104(CHEMBL4556378)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8BT3PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Medicines Research Centre

Curated by ChEMBL
LigandPNGBDBM50412613(CHEMBL481784)copy SMILEScopy InChI
Affinity DataIC50: 39.8nMAssay Description:Displacement of fluorescent labelled Dexamethasone from glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5V79PubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50535111(CHEMBL4590420)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8BT3PubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50535086(CHEMBL4469408)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8BT3PubMed
TargetAurora kinase B(Homo sapiens (Human))
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50535101(CHEMBL4444533)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminal-6His-tagged full length human Aurora B expressed in baculovirus using 5FAM-PKA-tide as substrate after 120 mins by fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM8BT3PubMed
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