Compile Data Set for Download or QSAR
Found 30 with Last Name = 'cheung' and Initial = 'tk'
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195608(CPI-455)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 7.0Assay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assays were carried out using full-length KDM5 enzymes in 384-well black ProxiPlates (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195608(CPI-455)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.0Assay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assays were carried out using full-length KDM5 enzymes in 384-well black ProxiPlates (...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195608(CPI-455)copy SMILEScopy InChI
Affinity DataIC50: 14nMpH: 7.0Assay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assays were carried out using full-length KDM5 enzymes in 384-well black ProxiPlates (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195610(KDM inhibitor, 3)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.0Assay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assays were carried out using full-length KDM5 enzymes in 384-well black ProxiPlates (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195608(CPI-455)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.0Assay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assays were carried out using full-length KDM5 enzymes in 384-well black ProxiPlates (...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195609(CPI-4203)copy SMILEScopy InChI
Affinity DataIC50: 77nMpH: 7.0Assay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assays were carried out using full-length KDM5 enzymes in 384-well black ProxiPlates (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM60875(3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:TR-FRET assays similar to those described above for KDM5 enzymes were carried out with full-length KDM2B, KDM3B, KDM4C, KDM6A and KDM7B.More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195609(CPI-4203)copy SMILEScopy InChI
Affinity DataIC50: 248nMpH: 7.0Assay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assays were carried out using full-length KDM5 enzymes in 384-well black ProxiPlates (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195609(CPI-4203)copy SMILEScopy InChI
Affinity DataIC50: 397nMpH: 7.0Assay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assays were carried out using full-length KDM5 enzymes in 384-well black ProxiPlates (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetLysine-specific demethylase 4C [1-350](Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195610(KDM inhibitor, 3)copy SMILEScopy InChI
Affinity DataIC50: 620nMpH: 7.5Assay Description:High-throughput MS assays were carried out using truncated KDM4C in 384-well V-bottom polypropylene plates (Greiner, Inc.). His-tagged recombinant KD...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetLysine-specific demethylase 5C(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM60875(3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMpH: 7.0Assay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assays were carried out using full-length KDM5 enzymes in 384-well black ProxiPlates (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195609(CPI-4203)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMpH: 7.0Assay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assays were carried out using full-length KDM5 enzymes in 384-well black ProxiPlates (...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetLysine-specific demethylase 4C [1-350](Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195608(CPI-455)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMpH: 7.5Assay Description:High-throughput MS assays were carried out using truncated KDM4C in 384-well V-bottom polypropylene plates (Greiner, Inc.). His-tagged recombinant KD...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM60875(3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMpH: 7.0Assay Description:Time-resolved fluorescence resonance energy transfer (TR-FRET) assays were carried out using full-length KDM5 enzymes in 384-well black ProxiPlates (...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 4C [1-350](Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195609(CPI-4203)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMpH: 7.5Assay Description:High-throughput MS assays were carried out using truncated KDM4C in 384-well V-bottom polypropylene plates (Greiner, Inc.). His-tagged recombinant KD...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetLysine-specific demethylase 6A(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM60875(3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:TR-FRET assays similar to those described above for KDM5 enzymes were carried out with full-length KDM2B, KDM3B, KDM4C, KDM6A and KDM7B.More data for this Ligand-Target Pair
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195608(CPI-455)copy SMILEScopy InChI
Affinity DataIC50: 7.70E+3nMAssay Description:TR-FRET assays similar to those described above for KDM5 enzymes were carried out with full-length KDM2B, KDM3B, KDM4C, KDM6A and KDM7B.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195608(CPI-455)copy SMILEScopy InChI
Affinity DataIC50: 9.10E+3nMAssay Description:TR-FRET assays similar to those described above for KDM5 enzymes were carried out with full-length KDM2B, KDM3B, KDM4C, KDM6A and KDM7B.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetLysine-specific demethylase 4C [1-350](Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM60875(3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+4nMpH: 7.5Assay Description:High-throughput MS assays were carried out using truncated KDM4C in 384-well V-bottom polypropylene plates (Greiner, Inc.). His-tagged recombinant KD...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetLysine-specific demethylase 3B(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195608(CPI-455)copy SMILEScopy InChI
Affinity DataIC50: 1.53E+4nMAssay Description:TR-FRET assays similar to those described above for KDM5 enzymes were carried out with full-length KDM2B, KDM3B, KDM4C, KDM6A and KDM7B.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetLysine-specific demethylase 3B(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195609(CPI-4203)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:TR-FRET assays similar to those described above for KDM5 enzymes were carried out with full-length KDM2B, KDM3B, KDM4C, KDM6A and KDM7B.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM60875(3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:TR-FRET assays similar to those described above for KDM5 enzymes were carried out with full-length KDM2B, KDM3B, KDM4C, KDM6A and KDM7B.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetLysine-specific demethylase 3B(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM60875(3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:TR-FRET assays similar to those described above for KDM5 enzymes were carried out with full-length KDM2B, KDM3B, KDM4C, KDM6A and KDM7B.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetLysine-specific demethylase 6A(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195609(CPI-4203)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:TR-FRET assays similar to those described above for KDM5 enzymes were carried out with full-length KDM2B, KDM3B, KDM4C, KDM6A and KDM7B.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195609(CPI-4203)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:TR-FRET assays similar to those described above for KDM5 enzymes were carried out with full-length KDM2B, KDM3B, KDM4C, KDM6A and KDM7B.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM60875(3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:TR-FRET assays similar to those described above for KDM5 enzymes were carried out with full-length KDM2B, KDM3B, KDM4C, KDM6A and KDM7B.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195608(CPI-455)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:TR-FRET assays similar to those described above for KDM5 enzymes were carried out with full-length KDM2B, KDM3B, KDM4C, KDM6A and KDM7B.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetLysine-specific demethylase 3B(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195608(CPI-455)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:TR-FRET assays similar to those described above for KDM5 enzymes were carried out with full-length KDM2B, KDM3B, KDM4C, KDM6A and KDM7B.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetLysine-specific demethylase 6A(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195608(CPI-455)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:TR-FRET assays similar to those described above for KDM5 enzymes were carried out with full-length KDM2B, KDM3B, KDM4C, KDM6A and KDM7B.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Genentech Inc

LigandPNGBDBM195609(CPI-4203)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:TR-FRET assays similar to those described above for KDM5 enzymes were carried out with full-length KDM2B, KDM3B, KDM4C, KDM6A and KDM7B.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CF9NXWPubMed