Compile Data Set for Download or QSAR
Found 288 with Last Name = 'oost' and Initial = 'tk'
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21450(N-Benylpiperazine derivative, 23r | N-[(4-{[(2R)-4...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM IC50: 60nM EC50:  40nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21449(N-Benylpiperazine derivative, 23q | N-[(4-{[(2R)-4...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM IC50: 60nM EC50:  130nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21439(N-Benylpiperazine derivative, 23g | N-[(4-{[(2R)-4...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM IC50: 60nM EC50:  430nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21441(N-Benylpiperazine derivative, 23i | N-[(4-{[(2R)-4...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM IC50: 60nM EC50:  18nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21436(N-Benylpiperazine derivative, 23d | N-[(4-{[(2R)-4...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM IC50: 60nM EC50:  95nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21444(N-Benylpiperazine derivative, 23m | N-[(4-{[(2R)-4...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM IC50: 60nM EC50:  30nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21421(4-Alkyl-4-methoxypiperidine derivative, 8m | N-[(4...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM ΔG°: <-53.1kJ/mole IC50: 60nM EC50:  35nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21420(4-Alkyl-4-methoxypiperidine derivative, 8l | 4-{4-...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM ΔG°: <-53.1kJ/mole IC50: 60nM EC50:  100nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21445(4-(4-{[2-(2-chlorophenyl)phenyl]methyl}piperazin-1...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM IC50: 60nM EC50:  56nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM IC50: 60nM EC50:  30nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21440(4-{4-[(2-cyclohexylphenyl)methyl]piperazin-1-yl}-N...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM IC50: 61nM EC50:  340nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21414(4-Alkyl-4-methoxypiperidine derivative, 8f | 4-{4-...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM ΔG°: <-53.1kJ/mole IC50: 62nM EC50:  230nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21418(4-Alkyl-4-methoxypiperidine derivative, 8j | N-[(4...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM ΔG°: <-53.1kJ/mole IC50: 71nM EC50:  150nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21435(N-Benylpiperazine derivative, 23c | N-[(4-{[(2R)-4...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM IC50: 80nM EC50:  390nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21442(N-Benylpiperazine derivative, 23k | N-[(4-{[(2R)-4...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM IC50: 81nM EC50:  800nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21432(4-Piperidinebenzylidene derivative, 10k | N-[(4-{[...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM IC50: 83nM EC50:  160nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21434(N-Benylpiperazine derivative, 23j | N-[(4-{[(2R)-4...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM IC50: 85nM EC50:  390nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21446(4-(4-{[2-(3-chlorophenyl)phenyl]methyl}piperazin-1...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM IC50: 140nM EC50:  180nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21415(4-Alkyl-4-methoxypiperidine derivative, 8g | 4-{4-...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM ΔG°: <-53.1kJ/mole IC50: 170nM EC50:  250nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21443(N-Benylpiperazine derivative, 23l | N-[(4-{[(2R)-4...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM IC50: 178nM EC50:  380nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21426(4-Piperidinebenzylidene derivative, 10e | N-[(4-{[...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM ΔG°: <-53.1kJ/mole IC50: 300nM EC50:  150nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21425(4-Piperidinebenzylidene derivative, 10d | 4-{4-[(4...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM ΔG°: <-53.1kJ/mole IC50: 510nM EC50:  620nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21429(4-Piperidinebenzylidene derivative, 10h | 4-{4-[(2...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM ΔG°: <-53.1kJ/mole IC50: 520nM EC50:  1.10E+3nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21424(4-Piperidinebenzylidene derivative, 10c | 4-{4-[(2...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM ΔG°: <-53.1kJ/mole IC50: 700nM EC50:  350nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21423(4-Piperidinebenzylidene derivative, 10b | N-[(4-{[...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM ΔG°: <-53.1kJ/mole IC50: 750nM EC50:  250nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21405(4-Piperidinebenzylidene derivative, 10a | N-[(4-{[...)copy SMILEScopy InChI
Affinity DataKi: <0.5nM ΔG°: <-53.1kJ/mole EC50:  380nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50181881(CHEMBL370837 | N-[2'-methoxy-4'-(3-morpholin-4-ylp...)copy SMILEScopy InChI
Affinity DataKi: <0.5nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4BT0PubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50181869(4-((R)-5-dimethylamino-1-phenylsulfanylmethylpenty...)copy SMILEScopy InChI
Affinity DataKi: <0.5nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4BT0PubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50181875(4-((R)-3-dimethylamino-1-phenylsulfanylmethylpropy...)copy SMILEScopy InChI
Affinity DataKi: <0.5nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4BT0PubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21438(4-(4-{[2-(cyclohexylamino)phenyl]methyl}piperazin-...)copy SMILEScopy InChI
Affinity DataKi:  0.600nM IC50: 370nM EC50:  660nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21428(4-Piperidinebenzylidene derivative, 10g | N-[(4-{[...)copy SMILEScopy InChI
Affinity DataKi:  0.600nM ΔG°:  -52.6kJ/mole IC50: 760nM EC50:  300nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21424(4-Piperidinebenzylidene derivative, 10c | 4-{4-[(2...)copy SMILEScopy InChI
Affinity DataKi:  0.700nM EC50:  450nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21413(4-Alkyl-4-methoxypiperidine derivative, 8d | 4-[4-...)copy SMILEScopy InChI
Affinity DataKi:  0.800nM ΔG°:  -51.9kJ/mole IC50: 300nM EC50:  320nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21400(CHEMBL192571 | N-[(4-{[(2R)-4-(dimethylamino)-1-(p...)copy SMILEScopy InChI
Affinity DataKi:  0.800nM ΔG°:  -51.9kJ/mole EC50:  470nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21400(CHEMBL192571 | N-[(4-{[(2R)-4-(dimethylamino)-1-(p...)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4BT0PubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50181889(4-((R)-5-amino-1-phenylsulfanylmethylpentylamino)-...)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4BT0PubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21417(4-Alkyl-4-methoxypiperidine derivative, 8i | N-[(4...)copy SMILEScopy InChI
Affinity DataKi:  0.900nM ΔG°:  -51.6kJ/mole IC50: 79nM EC50:  180nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21422(4-Alkyl-4-methoxypiperidine derivative, 8n | N-[(4...)copy SMILEScopy InChI
Affinity DataKi:  0.900nM ΔG°:  -51.6kJ/mole IC50: 160nM EC50:  600nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21437(N-Benylpiperazine derivative, 23e | N-[(4-{[(2R)-4...)copy SMILEScopy InChI
Affinity DataKi:  0.900nM IC50: 170nM EC50:  5.50E+3nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21416(4-Alkyl-4-methoxypiperidine derivative, 8h | 4-{4-...)copy SMILEScopy InChI
Affinity DataKi:  0.900nM ΔG°:  -51.6kJ/mole IC50: 200nM EC50:  400nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50181872(4-((R)-4-Dimethylamino-1-phenylsulfanylmethylbutyl...)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Binding affinity to Bcl-XL by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VM4BT0PubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21448(N-Benylpiperazine derivative, 23p | N-[(4-{[(2R)-4...)copy SMILEScopy InChI
Affinity DataKi:  1nM IC50: 100nM EC50:  22nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21445(4-(4-{[2-(2-chlorophenyl)phenyl]methyl}piperazin-1...)copy SMILEScopy InChI
Affinity DataKi: <1nM EC50:  27nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21449(N-Benylpiperazine derivative, 23q | N-[(4-{[(2R)-4...)copy SMILEScopy InChI
Affinity DataKi: <1nM EC50:  27nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21450(N-Benylpiperazine derivative, 23r | N-[(4-{[(2R)-4...)copy SMILEScopy InChI
Affinity DataKi: <1nM EC50:  13nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21451(N-Benylpiperazine derivative, 23s | N-[(4-{[(2R)-4...)copy SMILEScopy InChI
Affinity DataKi: <1nM EC50:  530nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)copy SMILEScopy InChI
Affinity DataKi: <1nM EC50:  8nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21448(N-Benylpiperazine derivative, 23p | N-[(4-{[(2R)-4...)copy SMILEScopy InChI
Affinity DataKi: <1nM EC50:  68nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21444(N-Benylpiperazine derivative, 23m | N-[(4-{[(2R)-4...)copy SMILEScopy InChI
Affinity DataKi: <1nM EC50:  25nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21443(N-Benylpiperazine derivative, 23l | N-[(4-{[(2R)-4...)copy SMILEScopy InChI
Affinity DataKi: <1nM EC50:  460nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69GVVPubMed
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