Compile Data Set for Download or QSAR
Found 35 with Last Name = 'vinh' and Initial = 'tk'
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10007(4-[(6-methoxy-1-benzofuran-2-yl)(1H-1,2,4-triazol-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10013(4-[(6-Hydroxybenzofuran-2-yl)-[1,2,4]triazol-1-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10000((4-fluorophenyl)(6-methoxy-1-benzofuran-2-yl)pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 44nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10005(1-[(4-chlorophenyl)(6-methoxy-1-benzofuran-2-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 44nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10004(1-[(4-fluorophenyl)(6-methoxy-1-benzofuran-2-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 49nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10001((4-chlorophenyl)(6-methoxy-1-benzofuran-2-yl)pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 49nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10014(2-[(4-Nitrophenyl)-[1,2,4]triazol-1-ylmethyl]benzo...)copy SMILEScopy InChI
Affinity DataIC50: 60nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10009(1-[(6-Methoxybenzofuran-2-yl)-p-tolylmethyl]-1H-1,...)copy SMILEScopy InChI
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10006(1-[(6-Methoxybenzofuran-2-yl)-(4-methoxyphenyl)met...)copy SMILEScopy InChI
Affinity DataIC50: 130nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10010(1-[(6-Methoxybenzofuran-2-yl)-(4-trifluoromethylph...)copy SMILEScopy InChI
Affinity DataIC50: 130nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10003(1-[(6-Methoxybenzofuran-2-yl)-(4-methoxyphenyl)met...)copy SMILEScopy InChI
Affinity DataIC50: 130nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10002((6-Methoxybenzofuran-2-yl)-(4-methoxyphenyl)-3-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 160nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM50079818(1-[(2,3-Dihydro-benzofuran-2-yl)-(4-fluoro-phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of human placental aromatase, cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8ZK7PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM50079814(1-[(4-Chloro-phenyl)-(2,3-dihydro-benzofuran-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human placental aromatase, cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8ZK7PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM50079820(1-[(2,3-Dihydro-benzofuran-2-yl)-p-tolyl-methyl]-1...)copy SMILEScopy InChI
Affinity DataIC50: 590nMAssay Description:Inhibition of human placental aromatase, cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8ZK7PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10008(1-[(6-Methoxybenzofuran-2-yl)-(4-nitrophenyl)methy...)copy SMILEScopy InChI
Affinity DataIC50: 600nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10015(2-[3-(1-cyano-1-methylethyl)-5-(1H-1,2,4-triazol-1...)copy SMILEScopy InChI
Affinity DataIC50: 600nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMedDrugBank
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM50079816(1-[(2,4-Dichloro-phenyl)-(2,3-dihydro-benzofuran-2...)copy SMILEScopy InChI
Affinity DataIC50: 880nMAssay Description:Inhibition of human placental aromatase, cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8ZK7PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10011(1-[(4-ethylphenyl)(6-methoxy-1-benzofuran-2-yl)met...)copy SMILEScopy InChI
Affinity DataIC50: 1.23E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM10012(2-[(4-Chlorophenyl)-[1,2,4]triazol-1-ylmethyl]benz...)copy SMILEScopy InChI
Affinity DataIC50: 1.46E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3C76PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM50079817(1-[(2,3-Dihydro-benzofuran-2-yl)-(4-fluoro-phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.17E+3nMAssay Description:Inhibition of human placental aromatase, cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8ZK7PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM50079815(1-[(4-Chloro-phenyl)-(2,3-dihydro-benzofuran-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human placental aromatase, cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8ZK7PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM85568(7-Hydroxy-flavone, 5c)copy SMILEScopy InChI
Affinity DataIC50: 1.01E+4nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FBSPubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM85567(7-Hydroxy-flavone, 5b)copy SMILEScopy InChI
Affinity DataIC50: 1.35E+4nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FBSPubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM26664(7-Hydroxy-flavone, 5a | 7-Hydroxyflavone, 11 | 7-h...)copy SMILEScopy InChI
Affinity DataIC50: 1.72E+4nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FBSPubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)copy SMILEScopy InChI
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of human placental aromatase, cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8ZK7PubMedDrugBank
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM50011438(2-(4-Amino-phenyl)-7-hydroxy-chromen-4-one | 2-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FBSPubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM85570(7-Hydroxy-flavone, 5e)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FBSPubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM50079819(1-[(2,4-Dichloro-phenyl)-(2,3-dihydro-benzofuran-2...)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of human placental aromatase, cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8ZK7PubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM85571(7-Hydroxy-flavone, 5f)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FBSPubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM85573(7-Hydroxy-flavone, 5h)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FBSPubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM85575(7-Hydroxy-flavone, 8)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FBSPubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM85569(7-Hydroxy-flavone, 5d)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FBSPubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM85574(7-Hydroxy-flavone, 7)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FBSPubMed
TargetAromatase(Homo sapiens (Human))
Cardiff University

LigandPNGBDBM85572(7-Hydroxy-flavone, 5g)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:The classical 3H2O assay was used to measure the effect of the flavones on aromatase activity using human placental microsomes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2FBSPubMed