Compile Data Set for Download or QSAR
Found 14 with Last Name = 'kapoor' and Initial = 'tm'
LigandPNGBDBM528572(US11192893, Example 12)copy SMILES
Affinity DataIC50: 290nMAssay Description:Compounds were tested employing a microtubule gliding assay, a standard biochemical assay for motor proteins. The first set of studies focused on hum...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6G18US Patent
LigandPNGBDBM528573(US11192893, Example 27)copy SMILES
Affinity DataIC50: 620nMAssay Description:Compounds were tested employing a microtubule gliding assay, a standard biochemical assay for motor proteins. The first set of studies focused on hum...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6G18US Patent
LigandPNGBDBM528576(US11192893, Example 31)copy SMILES
Affinity DataIC50: 710nMAssay Description:Compounds were tested employing a microtubule gliding assay, a standard biochemical assay for motor proteins. The first set of studies focused on hum...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6G18US Patent
LigandPNGBDBM528579(US11192893, Example 29)copy SMILES
Affinity DataIC50: 730nMAssay Description:Compounds were tested employing a microtubule gliding assay, a standard biochemical assay for motor proteins. The first set of studies focused on hum...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6G18US Patent
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Rockefeller University

Curated by ChEMBL
LigandPNGBDBM50326002(2-[4-acetamidyl phenylamino]-4-[2-benzoyl phenylam...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant polo-like kinase 1 activity by SDS-PAGEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0843PubMed
LigandPNGBDBM528571(US11192893, Example 5)copy SMILES
Affinity DataIC50: 2.60E+3nMAssay Description:Compounds were tested employing a microtubule gliding assay, a standard biochemical assay for motor proteins. The first set of studies focused on hum...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6G18US Patent
LigandPNGBDBM528570(US11192893, Example 4)copy SMILES
Affinity DataIC50: 3.30E+3nMAssay Description:Compounds were tested employing a microtubule gliding assay, a standard biochemical assay for motor proteins. The first set of studies focused on hum...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6G18US Patent
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Rockefeller University

Curated by ChEMBL
LigandPNGBDBM50263741(5-Cyano-7-nitro-3-oxy-benzothiazole-2-carboxylic a...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of recombinant polo-like kinase 1 activity by SDS-PAGEMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0843PubMed
TargetHistone-lysine N-methyltransferase SETD7(Homo sapiens (Human))
Rockefeller University

Curated by ChEMBL
LigandPNGBDBM50001750(CHEMBL3238424)copy SMILEScopy InChI
Affinity DataIC50: 9.93E+3nMAssay Description:Inhibition of methyl-transferase activity in GST-tagged recombinant SET7/9 (unknown origin) expressed in Escherichia coli BL21 using H3(1-20)-cys-bio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB54FGPubMed
TargetHistone-lysine N-methyltransferase SETD7(Homo sapiens (Human))
Rockefeller University

Curated by ChEMBL
LigandPNGBDBM50001750(CHEMBL3238424)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of 10 nM SET7 (unknown origin)-mediated methylation of histone H3(1-20)cys-biotin at 15 to 50 uM after 5 mins by scintillation proximity a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB54FGPubMed
TargetHistone-lysine N-methyltransferase SETD7(Homo sapiens (Human))
Rockefeller University

Curated by ChEMBL
LigandPNGBDBM50001750(CHEMBL3238424)copy SMILEScopy InChI
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibition of 100 nM SET7 (unknown origin)-mediated methylation of histone H3(1-20)cys-biotin at 15 to 50 uM after 5 mins by scintillation proximity ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB54FGPubMed
TargetHistone-lysine N-methyltransferase SETD7(Homo sapiens (Human))
Rockefeller University

Curated by ChEMBL
LigandPNGBDBM50001750(CHEMBL3238424)copy SMILEScopy InChI
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of 50 nM SET7 (unknown origin)-mediated methylation of histone H3(1-20)cys-biotin at 15 to 50 uM after 5 mins by scintillation proximity a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB54FGPubMed
TargetHistone-lysine N-methyltransferase SETD7(Homo sapiens (Human))
Rockefeller University

Curated by ChEMBL
LigandPNGBDBM50001750(CHEMBL3238424)copy SMILEScopy InChI
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of SET7 (unknown origin)-mediated methylation of histone H3(1-20)cys-biotin after 5 mins by scintillation proximity assay in presence of [...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB54FGPubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Rockefeller University

Curated by ChEMBL
LigandPNGBDBM50001750(CHEMBL3238424)copy SMILEScopy InChI
Affinity DataIC50: 2.64E+4nMAssay Description:Inhibition of C-terminal GST-tagged human G9a-mediated-methylation of histone3 expressed in Escherichia coli BL21(DE3) by MALDI-TOF mass spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB54FGPubMed