Compile Data Set for Download or QSAR
Found 7 with Last Name = 'hynes' and Initial = 'tr'
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

LigandPNGBDBM15413(4-(4-fluorophenyl)-5-[1-(propan-2-yl)-1H-1,2,3-ben...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RMPPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

LigandPNGBDBM15414(4-(4-fluorophenyl)-5-[3-(propan-2-yl)-[1,2,4]triaz...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Pfizer Inc

LigandPNGBDBM39807(CP-526,423)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.2 T: 2°CAssay Description:Human liver glycogen phsphorylase (HLGP) activity was measured in the direction of glycogen synthesis by the release of phosphate from glucose-1-phos...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PT2PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

LigandPNGBDBM15412(5-[4-(4-Fluoro-phenyl)-oxazol-5-yl]-1-isopropyl-3-...)copy SMILEScopy InChI
Affinity DataIC50: 30nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RMPPubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Pfizer Inc

LigandPNGBDBM50136446(1-{(S)-2-[(5-Chloro-1H-indole-2-carbonyl)-amino]-3...)copy SMILEScopy InChI
Affinity DataIC50: 45nMpH: 7.2 T: 2°CAssay Description:Human liver glycogen phsphorylase (HLGP) activity was measured in the direction of glycogen synthesis by the release of phosphate from glucose-1-phos...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Pfizer

LigandPNGBDBM15411(4-(4-fluorophenyl)-5-(pyridin-4-yl)-1,3-oxazole | ...)copy SMILEScopy InChI
Affinity DataIC50: 1.46E+3nMpH: 7.2 T: 2°CAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5RMPPubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Pfizer Inc

LigandPNGBDBM50149237(5-Chloro-1H-indole-2-carboxylic acid (2-methoxy-et...)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+4nMpH: 7.2 T: 2°CAssay Description:Human liver glycogen phsphorylase (HLGP) activity was measured in the direction of glycogen synthesis by the release of phosphate from glucose-1-phos...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41PT2PubMed