Compile Data Set for Download or QSAR
Found 54 with Last Name = 'johnson' and Initial = 'tr'
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50220643(6-((cyclopropylmethyl)(propyl)amino)-4-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HPQPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50220635(6-(butyl(methyl)amino)-4-(trifluoromethyl)nicotino...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HPQPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50220642(6-(sec-butyl(methyl)amino)-4-(trifluoromethyl)nico...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HPQPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM25437((trifluoromethyl)benzonitrile, 14 | 4-{[(1R,2S)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Antagonist activity at androgen receptor expressed in MDA-MB-453 cells assessed as inhibition of dihydrotestosterone-induced response in reporter gen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6BWTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50221436(4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzo...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Antagonist activity at androgen receptor expressed in MDA-MB-453 cells assessed as inhibition of dihydrotestosterone-induced response in reporter gen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6BWTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM25428(4-[3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxoimidaz...)copy SMILEScopy InChI
Affinity DataIC50: 15.9nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HPQPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM25428(4-[3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxoimidaz...)copy SMILEScopy InChI
Affinity DataIC50: 16nMpH: 7.4 T: 2°CAssay Description:The competitive radio-ligand binding analysis was performed on human AR extracts from transfected Sf9 cells in the presence or absence of differing c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31WZ1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM25432(6-{methyl[(1R)-1-phenylethyl]amino}-4-(trifluorome...)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.4 T: 2°CAssay Description:The competitive radio-ligand binding analysis was performed on human AR extracts from transfected Sf9 cells in the presence or absence of differing c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31WZ1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM25432(6-{methyl[(1R)-1-phenylethyl]amino}-4-(trifluorome...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HPQPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM25434(4-(2-hydroxycyclohexyl)-2-(trifluoromethyl)benzoni...)copy SMILEScopy InChI
Affinity DataIC50: 26nMpH: 7.4 T: 2°CAssay Description:The competitive radio-ligand binding analysis was performed on human AR extracts from transfected Sf9 cells in the presence or absence of differing c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31WZ1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50319612((R)-(+)-4-[4,4-Dimethyl-1-(4-methylsulfanyl-benzyl...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Antagonist activity at androgen receptor in human MDA-MB-453 cells coexpressing MMTV-ARE reporter gene assessed as inhibition of DHT-induced responseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM25428(4-[3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxoimidaz...)copy SMILEScopy InChI
Affinity DataIC50: 31.1nMAssay Description:Antagonist activity at human androgen receptor expressed in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HPQPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM25431(4-(2-hydroxyphenyl)-2-methoxybenzonitrile | diaryl...)copy SMILEScopy InChI
Affinity DataIC50: 37nMpH: 7.4 T: 2°CAssay Description:The competitive radio-ligand binding analysis was performed on human AR extracts from transfected Sf9 cells in the presence or absence of differing c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31WZ1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM25436(4-[(1R,2R)-2-hydroxycyclohexyl]-2-(trifluoromethyl...)copy SMILEScopy InChI
Affinity DataIC50: 37nMpH: 7.4 T: 2°CAssay Description:The competitive radio-ligand binding analysis was performed on human AR extracts from transfected Sf9 cells in the presence or absence of differing c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31WZ1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50319611((R)-4-(1-benzyl-4,4-dimethyl-2-oxopyrrolidin-3-ylo...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Antagonist activity at androgen receptor in human MDA-MB-453 cells coexpressing MMTV-ARE reporter gene assessed as inhibition of DHT-induced responseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM25430(4-(2-hydroxyphenyl)-2-(trifluoromethyl)benzonitril...)copy SMILEScopy InChI
Affinity DataIC50: 39.9nMpH: 7.4 T: 2°CAssay Description:The competitive radio-ligand binding analysis was performed on human AR extracts from transfected Sf9 cells in the presence or absence of differing c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31WZ1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50221435(4-((trans)-2-cyanocyclohexyloxy)-2-(trifluoromethy...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]DHT from androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6BWTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50319613((R)-(+)-4-(1-(2-Fluorobenzyl)-4,4-dimethyl-2-oxopy...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Antagonist activity at androgen receptor in human MDA-MB-453 cells coexpressing MMTV-ARE reporter gene assessed as inhibition of DHT-induced responseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM25432(6-{methyl[(1R)-1-phenylethyl]amino}-4-(trifluorome...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Antagonist activity at human androgen receptor expressed in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HPQPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50248594(4-(2-Fluorophenylthio)-2-(trifluoromethyl)benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Antagonist activity at androgen receptor in human MDA-MB-453 cells coexpressing MMTV-ARE reporter gene assessed as inhibition of DHT-induced responseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50221436(4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzo...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Displacement of [3H]DHT from androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6BWTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM25437((trifluoromethyl)benzonitrile, 14 | 4-{[(1R,2S)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Displacement of [3H]DHT from androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6BWTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM25437((trifluoromethyl)benzonitrile, 14 | 4-{[(1R,2S)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 60nMpH: 7.4 T: 2°CAssay Description:The competitive radio-ligand binding analysis was performed on human AR extracts from transfected Sf9 cells in the presence or absence of differing c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31WZ1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50319614(4-(2,4-Difluorophenoxy)-2-(trifluoromethyl)benzoni...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Antagonist activity at androgen receptor in human MDA-MB-453 cells coexpressing MMTV-ARE reporter gene assessed as inhibition of DHT-induced responseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50220640(6-(4-methylpiperidin-1-yl)-4-(trifluoromethyl)nico...)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HPQPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50220644(6-(dipropylamino)-4-(trifluoromethyl)nicotinonitri...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HPQPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50319611((R)-4-(1-benzyl-4,4-dimethyl-2-oxopyrrolidin-3-ylo...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]DHT from human AR expressed in baculovirus Sf9 cells system by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50220639(6-(methyl(1-phenylethyl)amino)-4-(trifluoromethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 123nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HPQPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50220640(6-(4-methylpiperidin-1-yl)-4-(trifluoromethyl)nico...)copy SMILEScopy InChI
Affinity DataIC50: 136nMAssay Description:Antagonist activity at human androgen receptor expressed in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HPQPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50220638(6-(octahydroisoquinolin-2(1H)-yl)-4-(trifluorometh...)copy SMILEScopy InChI
Affinity DataIC50: 169nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HPQPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50319613((R)-(+)-4-(1-(2-Fluorobenzyl)-4,4-dimethyl-2-oxopy...)copy SMILEScopy InChI
Affinity DataIC50: 174nMAssay Description:Displacement of [3H]DHT from human AR expressed in baculovirus Sf9 cells system by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50248594(4-(2-Fluorophenylthio)-2-(trifluoromethyl)benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 184nMAssay Description:Displacement of [3H]DHT from human AR expressed in baculovirus Sf9 cells system by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50221435(4-((trans)-2-cyanocyclohexyloxy)-2-(trifluoromethy...)copy SMILEScopy InChI
Affinity DataIC50: 196nMAssay Description:Antagonist activity at androgen receptor expressed in MDA-MB-453 cells assessed as inhibition of dihydrotestosterone-induced response in reporter gen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6BWTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50220641(6-(piperidin-1-yl)-4-(trifluoromethyl)nicotinonitr...)copy SMILEScopy InChI
Affinity DataIC50: 209nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HPQPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50220639(6-(methyl(1-phenylethyl)amino)-4-(trifluoromethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 229nMAssay Description:Antagonist activity at human androgen receptor expressed in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HPQPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50220638(6-(octahydroisoquinolin-2(1H)-yl)-4-(trifluorometh...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Antagonist activity at human androgen receptor expressed in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HPQPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50319612((R)-(+)-4-[4,4-Dimethyl-1-(4-methylsulfanyl-benzyl...)copy SMILEScopy InChI
Affinity DataIC50: 316nMAssay Description:Displacement of [3H]DHT from human AR expressed in baculovirus Sf9 cells system by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50220641(6-(piperidin-1-yl)-4-(trifluoromethyl)nicotinonitr...)copy SMILEScopy InChI
Affinity DataIC50: 422nMAssay Description:Antagonist activity at human androgen receptor expressed in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HPQPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50319614(4-(2,4-Difluorophenoxy)-2-(trifluoromethyl)benzoni...)copy SMILEScopy InChI
Affinity DataIC50: 488nMAssay Description:Displacement of [3H]DHT from human AR expressed in baculovirus Sf9 cells system by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50220643(6-((cyclopropylmethyl)(propyl)amino)-4-(trifluorom...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human androgen receptor expressed in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HPQPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50220642(6-(sec-butyl(methyl)amino)-4-(trifluoromethyl)nico...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human androgen receptor expressed in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HPQPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50220635(6-(butyl(methyl)amino)-4-(trifluoromethyl)nicotino...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human androgen receptor expressed in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HPQPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50220644(6-(dipropylamino)-4-(trifluoromethyl)nicotinonitri...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human androgen receptor expressed in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HPQPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM25435(4-[(1S,2S)-2-hydroxycyclohexyl]-2-(trifluoromethyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMpH: 7.4 T: 2°CAssay Description:The competitive radio-ligand binding analysis was performed on human AR extracts from transfected Sf9 cells in the presence or absence of differing c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31WZ1PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50220637((S)-6-(methyl(1-phenylethyl)amino)-4-(trifluoromet...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HPQPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM25433(4-[(1R,2S)-2-hydroxycyclohexyl]-2-(trifluoromethyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMpH: 7.4 T: 2°CAssay Description:The competitive radio-ligand binding analysis was performed on human AR extracts from transfected Sf9 cells in the presence or absence of differing c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31WZ1PubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50319611((R)-4-(1-benzyl-4,4-dimethyl-2-oxopyrrolidin-3-ylo...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMAssay Description:Binding affinity to progesterone receptor by PRB assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50319613((R)-(+)-4-(1-(2-Fluorobenzyl)-4,4-dimethyl-2-oxopy...)copy SMILEScopy InChI
Affinity DataIC50: 4.82E+3nMAssay Description:Binding affinity to progesterone receptor by PRB assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50220636((R)-6-(1-phenylethylamino)-4-(trifluoromethyl)nico...)copy SMILEScopy InChI
Affinity DataIC50: 4.93E+3nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9HPQPubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50248594(4-(2-Fluorophenylthio)-2-(trifluoromethyl)benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 6.95E+3nMAssay Description:Binding affinity to progesterone receptor by PRB assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
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