Compile Data Set for Download or QSAR
Found 106 with Last Name = 'kaoud' and Initial = 'ts'
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM50026646(CHEMBL3331466)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant COX2 pre-treated for 1 hr before 10-acetyl-3,7-dihydroxyphenoxazin substrate addition in absence of porcine liver est...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95BS4PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant COX2 pre-treated for 1 hr before 10-acetyl-3,7-dihydroxyphenoxazin substrate addition in absence of porcine liver est...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Minia University

LigandPNGBDBM13065(5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 66nMpH: 8.0 T: 2°CAssay Description:COX fluorescent inhibitor screening assay kit (catalog number 700100, Cayman chemical, Ann Arbour, MI, USA) has been employed to investigate the isoz...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J98KSPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM50029600(5-Bromo-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 70nMpH: 8.0 T: 2°CAssay Description:COX fluorescent inhibitor screening assay kit (catalog number 700100, Cayman chemical, Ann Arbour, MI, USA) has been employed to investigate the isoz...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J98KSPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50302943(4-(4-fluorophenyl)-5-(4-pyridyl)-1-(ethynyl)-2-(bu...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of p38alpha by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B02JMPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Minia University

LigandPNGBDBM50026646(CHEMBL3331466)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of purified ovine COX1 pre-treated for 1 hr before 10-acetyl-3,7-dihydroxyphenoxazin substrate addition in absence of porcine liver estera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95BS4PubMed
LigandPNGBDBM50559028(CHEMBL4740393)copy SMILES
Affinity DataIC50: 250nMAssay Description:Displacement of FAM-labeled 5-GpYLPQTV-NH2 from recombinant GST-tagged STAT3 (unknown origin) preincubated for 30 mins followed by FAM-labeled 5-GpYL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330GNPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Minia University

LigandPNGBDBM50026645(CHEMBL3331465)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of purified ovine COX1 pre-treated for 1 hr before 10-acetyl-3,7-dihydroxyphenoxazin substrate addition in presence of porcine liver ester...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95BS4PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Minia University

LigandPNGBDBM13066(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of purified ovine COX1 pre-treated for 1 hr before 10-acetyl-3,7-dihydroxyphenoxazin substrate addition in absence of porcine liver estera...More data for this Ligand-Target Pair
LigandPNGBDBM50559027(CHEMBL4747318)copy SMILES
Affinity DataIC50: 320nMAssay Description:Displacement of FAM-labeled 5-GpYLPQTV-NH2 from recombinant GST-tagged STAT3 (unknown origin) preincubated for 30 mins followed by FAM-labeled 5-GpYL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330GNPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50302944(2-(4-Fluorophenyl)-3(4-pyridinyl)-5-chloro-7-ethan...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of p38alpha by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B02JMPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM50021511(CHEMBL3290197)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant COX2 using ADHP as substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1S98PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM50021510(CHEMBL3290199)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Inhibition of human recombinant COX2 using ADHP as substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1S98PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Minia University

LigandPNGBDBM50026646(CHEMBL3331466)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of purified ovine COX1 pre-treated for 1 hr before 10-acetyl-3,7-dihydroxyphenoxazin substrate addition in presence of porcine liver ester...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95BS4PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50392849(CHEMBL2151190 | US9073941, 612)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of p38MAPKalpha using GST-ATF2 (1 to 115) as substrate preincubated for 30 mins before [gamma-32P]-ATP addition measured after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T9CPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392855(CHEMBL1969923)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:Inhibition of human JNK2alpha2 using GST-c-jun (1 to 221) as substrate preincubated for 30 mins before [gamma-32P]-ATP addition measured after 10 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T9CPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM50021505(CHEMBL3290204)copy SMILEScopy InChI
Affinity DataIC50: 660nMAssay Description:Inhibition of human recombinant COX2 using ADHP as substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1S98PubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392849(CHEMBL2151190 | US9073941, 612)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of human JNK2alpha2 using GST-c-jun (1 to 221) as substrate preincubated for 30 mins before [gamma-32P]-ATP addition measured after 10 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T9CPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM202550(N-{4-[(1Z)-1-(hydroxyimino)ethyl]phenyl}-2-{[5-(3,...)copy SMILEScopy InChI
Affinity DataIC50: 750nMpH: 8.0 T: 2°CAssay Description:COX fluorescent inhibitor screening assay kit (catalog number 700100, Cayman chemical, Ann Arbour, MI, USA) has been employed to investigate the isoz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J98KSPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Minia University

LigandPNGBDBM50022271(2-(3-Benzoylphenyl)propionic acid | 2-(3-benzoylph...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of purified ovine COX1 pre-treated for 1 hr before 10-acetyl-3,7-dihydroxyphenoxazin substrate addition in absence of porcine liver estera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95BS4PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM50021508(CHEMBL3290201)copy SMILEScopy InChI
Affinity DataIC50: 890nMAssay Description:Inhibition of human recombinant COX2 using ADHP as substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1S98PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Minia University

LigandPNGBDBM202549(N-{4-[(1Z)-1-(hydroxyimino)ethyl]phenyl}-2-{[5-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 980nMpH: 8.0 T: 2°CAssay Description:COX fluorescent inhibitor screening assay kit (catalog number 700100, Cayman chemical, Ann Arbour, MI, USA) has been employed to investigate the isoz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J98KSPubMed
TargetMitogen-activated protein kinase 1(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50392849(CHEMBL2151190 | US9073941, 612)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of rat ERK2 using Ets1 (1 to 138) as substrate preincubated for 30 mins before [gamma-32P]-ATP addition measured after 10 mins by liquid s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T9CPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM50026672(Bisfenazone)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant COX2 pre-treated for 1 hr before 10-acetyl-3,7-dihydroxyphenoxazin substrate addition in presence of porcine liver es...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95BS4PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM50026672(Bisfenazone)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant COX2 pre-treated for 1 hr before 10-acetyl-3,7-dihydroxyphenoxazin substrate addition in absence of porcine liver est...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95BS4PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Minia University

LigandPNGBDBM202547(N-(4-acetylphenyl)-2-[(5-phenyl-1,3,4-oxadiazol-2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMpH: 8.0 T: 2°CAssay Description:COX fluorescent inhibitor screening assay kit (catalog number 700100, Cayman chemical, Ann Arbour, MI, USA) has been employed to investigate the isoz...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J98KSPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM50026648(CHEMBL3331343)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant COX2 pre-treated for 1 hr before 10-acetyl-3,7-dihydroxyphenoxazin substrate addition in presence of porcine liver es...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95BS4PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM50021509(CHEMBL3290200)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant COX2 using ADHP as substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1S98PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM50021506(CHEMBL3290202)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant COX2 using ADHP as substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1S98PubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392855(CHEMBL1969923)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Displacement of FITC-JIP peptide from human His-tagged JNK2alpha2 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T9CPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM50026648(CHEMBL3331343)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant COX2 pre-treated for 1 hr before 10-acetyl-3,7-dihydroxyphenoxazin substrate addition in absence of porcine liver est...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95BS4PubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM50021507(CHEMBL3290203)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human recombinant COX2 using ADHP as substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1S98PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Minia University

LigandPNGBDBM202550(N-{4-[(1Z)-1-(hydroxyimino)ethyl]phenyl}-2-{[5-(3,...)copy SMILEScopy InChI
Affinity DataIC50: 2.12E+3nMpH: 8.0 T: 2°CAssay Description:COX fluorescent inhibitor screening assay kit (catalog number 700100, Cayman chemical, Ann Arbour, MI, USA) has been employed to investigate the isoz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J98KSPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM50026646(CHEMBL3331466)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant COX2 pre-treated for 1 hr before 10-acetyl-3,7-dihydroxyphenoxazin substrate addition in presence of porcine liver es...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95BS4PubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392856(CHEMBL1981814)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Displacement of FITC-JIP peptide from human His-tagged JNK2alpha2 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T9CPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392850(CHEMBL2151191)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Displacement of FITC-JIP peptide from human His-tagged JNK2alpha2 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T9CPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392856(CHEMBL1981814)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human JNK2alpha2 using GST-c-jun (1 to 221) as substrate preincubated for 30 mins before [gamma-32P]-ATP addition measured after 10 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T9CPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50392852(CHEMBL2151193)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of p38MAPKalpha using GST-ATF2 (1 to 115) as substrate preincubated for 30 mins before [gamma-32P]-ATP addition measured after 10 mins by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T9CPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392850(CHEMBL2151191)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human JNK2alpha2 using GST-c-jun (1 to 221) as substrate preincubated for 30 mins before [gamma-32P]-ATP addition measured after 10 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T9CPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50392854(CHEMBL1980140)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human JNK2alpha2 using GST-c-jun (1 to 221) as substrate preincubated for 30 mins before [gamma-32P]-ATP addition measured after 10 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T9CPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM202549(N-{4-[(1Z)-1-(hydroxyimino)ethyl]phenyl}-2-{[5-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMpH: 8.0 T: 2°CAssay Description:COX fluorescent inhibitor screening assay kit (catalog number 700100, Cayman chemical, Ann Arbour, MI, USA) has been employed to investigate the isoz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J98KSPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM50022271(2-(3-Benzoylphenyl)propionic acid | 2-(3-benzoylph...)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human recombinant COX2 pre-treated for 1 hr before 10-acetyl-3,7-dihydroxyphenoxazin substrate addition in absence of porcine liver est...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95BS4PubMedDrugBank
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50302943(4-(4-fluorophenyl)-5-(4-pyridyl)-1-(ethynyl)-2-(bu...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human MAP4K4 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B02JMPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Minia University

Curated by ChEMBL
LigandPNGBDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human recombinant COX2 pre-treated for 1 hr before 10-acetyl-3,7-dihydroxyphenoxazin substrate addition in absence of porcine liver est...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50392851(CHEMBL2151192)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of rat ERK2 using Ets1 (1 to 138) as substrate preincubated for 30 mins before [gamma-32P]-ATP addition measured after 10 mins by liquid s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6T9CPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Minia University

LigandPNGBDBM50026648(CHEMBL3331343)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of purified ovine COX1 pre-treated for 1 hr before 10-acetyl-3,7-dihydroxyphenoxazin substrate addition in presence of porcine liver ester...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95BS4PubMed
LigandPNGBDBM50559027(CHEMBL4747318)copy SMILES
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of STAT3 in human SB-590885-resistant 451Lu cells assessed as reduction in STAT3 transcriptional activity measured after 12 hrs by Dual-lu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330GNPubMed
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
The University of Texas at Austin

Curated by ChEMBL
LigandPNGBDBM50302943(4-(4-fluorophenyl)-5-(4-pyridyl)-1-(ethynyl)-2-(bu...)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of p38beta by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B02JMPubMed
LigandPNGBDBM50559027(CHEMBL4747318)copy SMILES
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of STAT3 in human SB-590885-sensitive 451Lu cells assessed as reduction in STAT3 transcriptional activity measured after 12 hrs by Dual-lu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M330GNPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Minia University

LigandPNGBDBM50026645(CHEMBL3331465)copy SMILEScopy InChI
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of purified ovine COX1 pre-treated for 1 hr before 10-acetyl-3,7-dihydroxyphenoxazin substrate addition in absence of porcine liver estera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95BS4PubMed
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