BindingDB PrimarySearch

Found 553 with Last Name = 'miguel' and Initial = 'ts'

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50401261(CHEMBL2206921 | US8772480, 384)copy SMILEScopy InChI

Ki: 0.400nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110delta expressed in baculovirus infected Hi5 cells using Phosphatidylinositol-4,5-bisphosphate ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2MG7QNWPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50401261(CHEMBL2206921 | US8772480, 384)copy SMILEScopy InChI

Ki: 0.600nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110beta expressed in baculovirus infected Hi5 cells using Phosphatidylinositol-4,5-bisphosphate a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2MG7QNWPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50396807(CHEMBL2170082 | US8772480, 316)copy SMILEScopy InChI

Ki: 1nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf9 cells using phosphatidylinositol-4,5-bisp...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2028SPTPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50396806(CHEMBL2170083 | US8772480, 270)copy SMILEScopy InChI

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2028SPTPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50396808(CHEMBL2170081 | US8772480, 148)copy SMILEScopy InChI

Ki: 1nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110gamma expressed in baculovirus infected Hi5 cells using ATP as substrate after 20 mins by spec...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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BindingDB Entry DOI: 10.7270/Q2028SPTPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50401261(CHEMBL2206921 | US8772480, 384)copy SMILEScopy InChI

Ki: 1nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110gamma expressed in baculovirus infected Hi5 cells using Phosphatidylinositol-4,5-bisphosphate ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2MG7QNWPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50396809(CHEMBL2170099 | US8772480, 147)copy SMILEScopy InChI

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2028SPTPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50394838(CHEMBL2165007 | US8772480, 141)copy SMILEScopy InChI

Ki: 1nMAssay Description:Inhibition of human N-terminal poly-His tagged-PI3Kdelta expressed in Sf9 baculovirus system co-expressing p85alpha after 20 mins by AlphaScreen assa...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q23F4QSJPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50396820(CHEMBL2170088 | US8772480, 272)copy SMILEScopy InChI

Ki: 1nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110alpha/p85alpha expressed in baculovirus infected Sf9 cells using phosphatidylinositol-4,5-bisp...More data for this Ligand-Target Pair

PDB
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Details Article
BindingDB Entry DOI: 10.7270/Q2028SPTPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50401256(CHEMBL2206904 | US8772480, 331)copy SMILEScopy InChI

Ki: 1.10nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110delta expressed in baculovirus infected Hi5 cells using Phosphatidylinositol-4,5-bisphosphate ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2MG7QNWPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50401269(CHEMBL2206913)copy SMILEScopy InChI

Ki: 1.20nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110delta expressed in baculovirus infected Hi5 cells using Phosphatidylinositol-4,5-bisphosphate ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2MG7QNWPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50401251(CHEMBL2206909)copy SMILEScopy InChI

Ki: 1.90nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110alpha expressed in baculovirus infected Hi5 cells using Phosphatidylinositol-4,5-bisphosphate ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2MG7QNWPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50396821(CHEMBL2170087 | US8772480, 361)copy SMILEScopy InChI

Ki: 2nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110alpha/p85alpha expressed in baculovirus infected Sf9 cells using phosphatidylinositol-4,5-bisp...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2028SPTPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50396821(CHEMBL2170087 | US8772480, 361)copy SMILEScopy InChI

Ki: 2nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf9 cells using phosphatidylinositol-4,5-bisp...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2028SPTPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50401253(CHEMBL2206907 | US8772480, 328)copy SMILEScopy InChI

Ki: 2nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110alpha expressed in baculovirus infected Hi5 cells using Phosphatidylinositol-4,5-bisphosphate ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL MMDB PC cid PC sid PDB Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2MG7QNWPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50396808(CHEMBL2170081 | US8772480, 148)copy SMILEScopy InChI

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

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BindingDB Entry DOI: 10.7270/Q2028SPTPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50396806(CHEMBL2170083 | US8772480, 270)copy SMILEScopy InChI

PDB
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2028SPTPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50394892(CHEMBL2165051)copy SMILEScopy InChI

Ki: 2nMAssay Description:Inhibition of human N-terminal poly-His tagged-PI3Kalpha expressed in Sf9 baculovirus system co-expressing p85alpha after 20 mins by AlphaScreen assa...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q23F4QSJPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50396822(CHEMBL2170086 | US8772480, 360)copy SMILEScopy InChI

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2028SPTPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50394838(CHEMBL2165007 | US8772480, 141)copy SMILEScopy InChI

Ki: 2nMAssay Description:Inhibition of human N-terminal poly-His tagged-PI3Kbeta expressed in Sf9 baculovirus system co-expressing p85alpha after 20 mins by AlphaScreen assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q23F4QSJPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50394846(CHEMBL2165017 | US8772480, 35)copy SMILEScopy InChI

Ki: 2nMAssay Description:Inhibition of human N-terminal poly-His tagged-PI3Kdelta expressed in Sf9 baculovirus system co-expressing p85alpha after 20 mins by AlphaScreen assa...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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BindingDB Entry DOI: 10.7270/Q23F4QSJPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50394860(CHEMBL2165030 | US8772480, 256)copy SMILEScopy InChI

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q23F4QSJPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50394860(CHEMBL2165030 | US8772480, 256)copy SMILEScopy InChI

Ki: 2nMAssay Description:Inhibition of human N-terminal poly-His tagged-PI3Kgamma expressed in Sf9 baculovirus system co-expressing p85alpha after 20 mins by AlphaScreen assa...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q23F4QSJPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50401256(CHEMBL2206904 | US8772480, 331)copy SMILEScopy InChI

Ki: 2.20nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110gamma expressed in baculovirus infected Hi5 cells using Phosphatidylinositol-4,5-bisphosphate ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2MG7QNWPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50401269(CHEMBL2206913)copy SMILEScopy InChI

Ki: 2.40nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110gamma expressed in baculovirus infected Hi5 cells using Phosphatidylinositol-4,5-bisphosphate ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2MG7QNWPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50396807(CHEMBL2170082 | US8772480, 316)copy SMILEScopy InChI

Ki: 3nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110alpha/p85alpha expressed in baculovirus infected Sf9 cells using phosphatidylinositol-4,5-bisp...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
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CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2028SPTPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50394838(CHEMBL2165007 | US8772480, 141)copy SMILEScopy InChI

Ki: 3nMAssay Description:Inhibition of human N-terminal poly-His tagged-PI3Kalpha expressed in Sf9 baculovirus system co-expressing p85alpha after 20 mins by AlphaScreen assa...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q23F4QSJPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50394891(CHEMBL2165052 | US8772480, 23)copy SMILEScopy InChI

Ki: 3nMAssay Description:Inhibition of human N-terminal poly-His tagged-PI3Kbeta expressed in Sf9 baculovirus system co-expressing p85alpha after 20 mins by AlphaScreen assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q23F4QSJPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50394860(CHEMBL2165030 | US8772480, 256)copy SMILEScopy InChI

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q23F4QSJPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50394847(CHEMBL2165016)copy SMILEScopy InChI

Ki: 3nMAssay Description:Inhibition of human N-terminal poly-His tagged-PI3Kdelta expressed in Sf9 baculovirus system co-expressing p85alpha after 20 mins by AlphaScreen assa...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q23F4QSJPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50394841(CHEMBL2165004 | US8772480, 228)copy SMILEScopy InChI

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q23F4QSJPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50394844(CHEMBL2165019 | US8772480, 224)copy SMILEScopy InChI

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q23F4QSJPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50394892(CHEMBL2165051)copy SMILEScopy InChI

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q23F4QSJPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50396805(CHEMBL2170084)copy SMILEScopy InChI

Ki: 3nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf9 cells using phosphatidylinositol-4,5-bisp...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2028SPTPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50401264(CHEMBL2206918)copy SMILEScopy InChI

Ki: 3.5nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110alpha expressed in baculovirus infected Hi5 cells using Phosphatidylinositol-4,5-bisphosphate ...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2MG7QNWPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50396809(CHEMBL2170099 | US8772480, 147)copy SMILEScopy InChI

Ki: 4nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110alpha/p85alpha expressed in baculovirus infected Sf9 cells using phosphatidylinositol-4,5-bisp...More data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q2028SPTPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50396819(CHEMBL2170089 | US8772480, 271)copy SMILEScopy InChI

PDB
UniProtKB/SwissProt
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CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2028SPTPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50396818(CHEMBL2170090 | US8772480, 280)copy SMILEScopy InChI

PDB
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2028SPTPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50394892(CHEMBL2165051)copy SMILEScopy InChI

Ki: 4nMAssay Description:Inhibition of human N-terminal poly-His tagged-PI3Kbeta expressed in Sf9 baculovirus system co-expressing p85alpha after 20 mins by AlphaScreen assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q23F4QSJPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50394892(CHEMBL2165051)copy SMILEScopy InChI

Ki: 4nMAssay Description:Inhibition of human N-terminal poly-His tagged-PI3Kgamma expressed in Sf9 baculovirus system co-expressing p85alpha after 20 mins by AlphaScreen assa...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q23F4QSJPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50394846(CHEMBL2165017 | US8772480, 35)copy SMILEScopy InChI

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Details Article
BindingDB Entry DOI: 10.7270/Q23F4QSJPubMed PDB

3D Structure (crystal)

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50396808(CHEMBL2170081 | US8772480, 148)copy SMILEScopy InChI

PDB
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar

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Details Article
BindingDB Entry DOI: 10.7270/Q2028SPTPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50394861(CHEMBL2165029)copy SMILEScopy InChI

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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BindingDB Entry DOI: 10.7270/Q23F4QSJPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50394861(CHEMBL2165029)copy SMILEScopy InChI

Ki: 4nMAssay Description:Inhibition of human N-terminal poly-His tagged-PI3Kdelta expressed in Sf9 baculovirus system co-expressing p85alpha after 20 mins by AlphaScreen assa...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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CHEMBL PC cid PC sid Similars

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BindingDB Entry DOI: 10.7270/Q23F4QSJPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50394843(CHEMBL2165020 | US8772480, 155)copy SMILEScopy InChI

PDB MMDB NCI pathway Reactome pathway KEGG
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CHEMBL PC cid PC sid

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BindingDB Entry DOI: 10.7270/Q23F4QSJPubMed

Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50394846(CHEMBL2165017 | US8772480, 35)copy SMILEScopy InChI

Ki: 4nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf9 cells using phosphatidylinositol-4,5-bisp...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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BindingDB Entry DOI: 10.7270/Q2028SPTPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50401269(CHEMBL2206913)copy SMILEScopy InChI

Ki: 4.40nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110beta expressed in baculovirus infected Hi5 cells using Phosphatidylinositol-4,5-bisphosphate a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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CHEMBL PC cid PC sid Similars

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BindingDB Entry DOI: 10.7270/Q2MG7QNWPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50401256(CHEMBL2206904 | US8772480, 331)copy SMILEScopy InChI

Ki: 4.70nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110beta expressed in baculovirus infected Hi5 cells using Phosphatidylinositol-4,5-bisphosphate a...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2MG7QNWPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50394841(CHEMBL2165004 | US8772480, 228)copy SMILEScopy InChI

Ki: 5nMAssay Description:Inhibition of human N-terminal poly-His tagged-PI3Kbeta expressed in Sf9 baculovirus system co-expressing p85alpha after 20 mins by AlphaScreen assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q23F4QSJPubMed

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL

BDBM50394841(CHEMBL2165004 | US8772480, 228)copy SMILEScopy InChI

Ki: 5nMAssay Description:Inhibition of human N-terminal poly-His tagged-PI3Kgamma expressed in Sf9 baculovirus system co-expressing p85alpha after 20 mins by AlphaScreen assa...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q23F4QSJPubMed

Displayed 1 to 50 (of 553 total ) | Next | Last >>

Targets 16 ▿
- Serine/threonine-protein kinase mTOR 81
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 81
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 79
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 61
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 61
- Cell division cycle 7-related protein kinase 43
- Beta-secretase 1 42
- Cyclin-dependent kinase 2 35
- Phosphatidylinositol 3-kinase catalytic subunit type 3 25
- Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform 20
- Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 20
- Phosphatidylinositol 4-kinase alpha 1
- DNA-dependent protein kinase catalytic subunit 1
- Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 1
- Phosphatidylinositol 4-kinase beta 1
- Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha 1
- ...
Publications 5 ▿
- J Med Chem 55: 5188-219 (2012) 293
- J Med Chem 55: 7796-816 (2012) 100
- Bioorg Med Chem Lett 23: 2056-60 (2013) 78
- ACS Med Chem Lett 3: 886-891 (2012) 42
- Bioorg Med Chem Lett 22: 5714-20 (2012) 40
Institutions 2 ▿
- [Amgen Inc.] 511
- [TBA] 42
Affinity: 0.40 to 8.3E+4 nM▿
- Ki 322
- IC50 231
- Affinity ≤ nM
Xtal structures: 5
Docked structures: 0
Catalog Cmpds: 4