Compile Data Set for Download or QSAR
Found 49 with Last Name = 'snowden' and Initial = 'ts'
LigandPNGBDBM50396023(CHEMBL2169919)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]-SAM in recombinant human His-tagged DOT1L (1 to 416 residues) expressed in Escherichia coli BL21-Gold (DE3) cells incubated for ...More data for this Ligand-Target Pair
LigandPNGBDBM50396023(CHEMBL2169919)copy SMILEScopy InChI
Affinity DataIC50: 0.860nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human DNMT1 using poly(dl-dC) as substrate by hotspot assayMore data for this Ligand-Target Pair
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human PRMT8 using histone H4 as substrate by hotspot assayMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 7(Homo sapiens (Human))TBA
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human PRMT7 using GST-GAR as substrate by hotspot assayMore data for this Ligand-Target Pair
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:Inhibition of recombinant human PRMT3 using histone H4 as substrate by hotspot assayMore data for this Ligand-Target Pair
LigandPNGBDBM50551137(CHEMBL4765125)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))TBA
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)copy SMILEScopy InChI
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of recombinant human G9a using histone H3 (1 to 21) as substrate by hotspot assayMore data for this Ligand-Target Pair
LigandPNGBDBM50551132(CHEMBL4777038)copy SMILES
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551136(CHEMBL4757320)copy SMILES
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551135(CHEMBL4740900)copy SMILES
Affinity DataIC50: 2.24E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))TBA
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)copy SMILEScopy InChI
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of recombinant human EZH2 using core histone as substrate by hotspot assayMore data for this Ligand-Target Pair
LigandPNGBDBM50551134(CHEMBL4761584)copy SMILES
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551136(CHEMBL4757320)copy SMILES
Affinity DataIC50: 2.53E+4nMAssay Description:Inhibition of recombinant human PRMT3 using histone H4 as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551120(CHEMBL1889068)copy SMILES
Affinity DataIC50: 3.24E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using nucleosome as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551130(CHEMBL4757791)copy SMILES
Affinity DataIC50: 3.69E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551128(CHEMBL1700259)copy SMILES
Affinity DataIC50: 4.08E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551136(CHEMBL4757320)copy SMILES
Affinity DataIC50: 5.36E+4nMAssay Description:Inhibition of recombinant human PRMT8 using histone H4 as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551121(CHEMBL1701619)copy SMILES
Affinity DataIC50: 5.49E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using nucleosome as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551142(CHEMBL4755929)copy SMILES
Affinity DataIC50: 5.56E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551122(CHEMBL3183870)copy SMILES
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using nucleosome as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))TBA
LigandPNGBDBM50551136(CHEMBL4757320)copy SMILES
Affinity DataIC50: 6.14E+4nMAssay Description:Inhibition of recombinant human G9a using histone H3 (1 to 21) as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetProtein arginine N-methyltransferase 7(Homo sapiens (Human))TBA
LigandPNGBDBM50551136(CHEMBL4757320)copy SMILES
Affinity DataIC50: 6.15E+4nMAssay Description:Inhibition of recombinant human PRMT7 using GST-GAR as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551131(CHEMBL4787257)copy SMILES
Affinity DataIC50: 6.92E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetProtein arginine N-methyltransferase 7(Homo sapiens (Human))TBA
LigandPNGBDBM50551131(CHEMBL4787257)copy SMILES
Affinity DataIC50: 6.94E+4nMAssay Description:Inhibition of recombinant human PRMT7 using GST-GAR as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetHistone-lysine N-methyltransferase SETD7(Homo sapiens (Human))TBA
LigandPNGBDBM50551136(CHEMBL4757320)copy SMILES
Affinity DataIC50: 7.98E+4nMAssay Description:Inhibition of recombinant human SET7/9 using core histone as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551128(CHEMBL1700259)copy SMILES
Affinity DataIC50: 8.29E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using nucleosome as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551123(CHEMBL4790104)copy SMILES
Affinity DataIC50: 8.53E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using nucleosome as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551124(CHEMBL1719780)copy SMILES
Affinity DataIC50: 9.04E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using nucleosome as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551140(CHEMBL4755253)copy SMILES
Affinity DataIC50: 9.49E+4nMAssay Description:Inhibition of recombinant human PRMT8 using histone H4 as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551138(CHEMBL4761832)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551141(CHEMBL4748970)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551140(CHEMBL4755253)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551139(CHEMBL4794865)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50551136(CHEMBL4757320)copy SMILES
Affinity DataIC50: 1.13E+5nMAssay Description:Inhibition of recombinant human PRMT5 using histone H2A as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551137(CHEMBL4765125)copy SMILES
Affinity DataIC50: 1.15E+5nMAssay Description:Inhibition of recombinant human PRMT3 using histone H4 as substrate by hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551125(CHEMBL1704660)copy SMILES
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using nucleosome as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551127(CHEMBL1707713)copy SMILES
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using nucleosome as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551133(CHEMBL4741080)copy SMILES
Affinity DataIC50: 1.38E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using histone as substrate i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))TBA
LigandPNGBDBM50551137(CHEMBL4765125)copy SMILES
Affinity DataIC50: 1.65E+5nMAssay Description:Inhibition of recombinant human PRMT5 using histone H2A as substrate by hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551126(CHEMBL1723900)copy SMILES
Affinity DataIC50: 1.68E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using nucleosome as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551131(CHEMBL4787257)copy SMILES
Affinity DataIC50: 2.16E+5nMAssay Description:Inhibition of recombinant human PRMT8 using histone H4 as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50551137(CHEMBL4765125)copy SMILES
Affinity DataIC50: 2.48E+5nMAssay Description:Inhibition of recombinant human DNMT1 using poly(dl-dC) as substrate by hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551137(CHEMBL4765125)copy SMILES
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of recombinant human PRMT8 using histone H4 as substrate by hotspot assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetHistone-lysine N-methyltransferase EZH2(Homo sapiens (Human))TBA
LigandPNGBDBM50551135(CHEMBL4740900)copy SMILES
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of recombinant human EZH2 using core histone as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50551132(CHEMBL4777038)copy SMILES
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of recombinant human DNMT1 using poly(dl-dC) as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))TBA
LigandPNGBDBM50551135(CHEMBL4740900)copy SMILES
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of recombinant human G9a using histone H3 (1 to 21) as substrate by hotspot assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM91422((phenylmethyl) N-[1-[3-(1,3-benzodioxol-5-ylmethyl...)copy SMILEScopy InChI
Affinity DataIC50: 6.78E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using nucleosome as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed
LigandPNGBDBM50551129(CHEMBL4752372)copy SMILES
Affinity DataIC50: 7.10E+5nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DOT1L (1 to 420 residues) expressed in Escherichia coli BL21 (DE3) using nucleosome as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB1BJ6PubMed