Compile Data Set for Download or QSAR
Found 184 with Last Name = 'banerjee' and Initial = 'u'
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50357677(CHEMBL1914951)copy SMILEScopy InChI
Affinity DataKi:  7.50E+4nMAssay Description:Competitive inhibition of human topoisomerase-2 alpha-ATPase activity by Lineweaver-Burk assay in presence of 200 to 520 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3KW8PubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM22369(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8H5QPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327527(2-(4-bromophenyl)-N-((7-methoxy-2-(pyridin-4-yl)qu...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327528(2-(4-bromophenyl)-N-((7-methoxy-2-(pyridin-3-yl)qu...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327516(2-(4-bromophenyl)-N-((7-methoxy-2-(thiophen-3-yl)q...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327540(3-((4-bromophenethylamino)methyl)-2-(thiophen-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327521(2-(4-chlorophenyl)-N-((7-methoxy-2-(thiophen-3-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 97nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM21679((2S,4R)-4-[(1S,2S,5R,7S,8R,9R,10S,11S,14R,15R)-8-e...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Mus musculus)
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM21679((2S,4R)-4-[(1S,2S,5R,7S,8R,9R,10S,11S,14R,15R)-8-e...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Agonist activity at mouse TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Mus musculus)
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327538(3-((4-bromophenethylamino)methyl)-2-(thiophen-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Agonist activity at mouse TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrateMore data for this Ligand-Target Pair
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 293nMAssay Description:Inhibition of recombinant human COX2 assessed as reduction in PGF2alpha incubated for 2 mins using arachidonic acid as substrate by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8H5QPubMed
TargetG-protein coupled bile acid receptor 1(Mus musculus)
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327541(3-((4-bromophenethylamino)methyl)-7-methoxy-2-(thi...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Agonist activity at mouse TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50515743(CHEMBL4448990)copy SMILEScopy InChI
Affinity DataIC50: 367nMAssay Description:Inhibition of recombinant human COX2 assessed as reduction in PGF2alpha incubated for 2 mins using arachidonic acid as substrate by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8H5QPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50019936(CHEMBL3287559)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0VF9PubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327541(3-((4-bromophenethylamino)methyl)-7-methoxy-2-(thi...)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327526(2-(4-bromophenyl)-N-((7-methoxy-2-phenylquinolin-3...)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327525(2-(4-bromophenyl)-N-((2-(furan-2-yl)-7-methoxyquin...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50515744(CHEMBL4441570)copy SMILEScopy InChI
Affinity DataIC50: 513nMAssay Description:Inhibition of recombinant human COX2 assessed as reduction in PGF2alpha incubated for 2 mins using arachidonic acid as substrate by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8H5QPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327523(2-(4-bromophenyl)-N-((7-methoxy-2-(thiophen-2-yl)q...)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327520(CHEMBL1258310 | N-(4-chlorobenzyl)-1-(7-methoxy-2-...)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50019935(CHEMBL3287567)copy SMILEScopy InChI
Affinity DataIC50: 670nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0VF9PubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327524(2-(4-bromophenyl)-N-((2-(furan-3-yl)-7-methoxyquin...)copy SMILEScopy InChI
Affinity DataIC50: 710nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327518(1-(7-methoxy-2-(thiophen-3-yl)quinolin-3-yl)-N-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 880nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50515745(CHEMBL4474644)copy SMILEScopy InChI
Affinity DataIC50: 915nMAssay Description:Inhibition of recombinant human COX2 assessed as reduction in PGF2alpha incubated for 2 mins using arachidonic acid as substrate by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8H5QPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327519(1-(7-methoxy-2-(thiophen-3-yl)quinolin-3-yl)-N-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50019937(CHEMBL3287560)copy SMILEScopy InChI
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0VF9PubMed
TargetG-protein coupled bile acid receptor 1(Mus musculus)
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327540(3-((4-bromophenethylamino)methyl)-2-(thiophen-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Agonist activity at mouse TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Indo-Soviet Friendship College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50351346(CHEMBL1818919)copy SMILEScopy InChI
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of bovine milk xanthine oxidase assessed as decrease of uric acid formation preincubated for 5 mins by UV-visible spectrophotometric analy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22R3S2CPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327531(2-(4-bromophenyl)-N-((7-methoxy-2-(oxazol-2-yl)qui...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327522(2-(3-bromophenyl)-N-((7-methoxy-2-(thiophen-3-yl)q...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Mus musculus)
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327516(2-(4-bromophenyl)-N-((7-methoxy-2-(thiophen-3-yl)q...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:Agonist activity at mouse TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Mus musculus)
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327521(2-(4-chlorophenyl)-N-((7-methoxy-2-(thiophen-3-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Agonist activity at mouse TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Mus musculus)
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327527(2-(4-bromophenyl)-N-((7-methoxy-2-(pyridin-4-yl)qu...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Agonist activity at mouse TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Mus musculus)
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327518(1-(7-methoxy-2-(thiophen-3-yl)quinolin-3-yl)-N-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Agonist activity at mouse TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Mus musculus)
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327525(2-(4-bromophenyl)-N-((2-(furan-2-yl)-7-methoxyquin...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Agonist activity at mouse TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Mus musculus)
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327520(CHEMBL1258310 | N-(4-chlorobenzyl)-1-(7-methoxy-2-...)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMAssay Description:Agonist activity at mouse TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327534(2-(4-bromophenyl)-N-((7-ethoxy-2-(thiophen-3-yl)qu...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Mus musculus)
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327523(2-(4-bromophenyl)-N-((7-methoxy-2-(thiophen-2-yl)q...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Agonist activity at mouse TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327530(2-(4-bromophenyl)-N-((7-methoxy-2-(thiazol-2-yl)qu...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Mus musculus)
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327528(2-(4-bromophenyl)-N-((7-methoxy-2-(pyridin-3-yl)qu...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Agonist activity at mouse TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327532(2-(4-bromophenyl)-N-((7-methyl-2-(thiophen-3-yl)qu...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327538(3-((4-bromophenethylamino)methyl)-2-(thiophen-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+3nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Mus musculus)
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM21680((4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R,16S)-5,9,1...)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+3nMAssay Description:Agonist activity at mouse TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Indo-Soviet Friendship College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50338853(1-(3-(Furan-2-yl)-4,5-dihydro-5-(pyridin-4-yl)pyra...)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of bovine Xanthine oxidase assessed as decrease in uric acid production preincubated at 293 nM of compound for 5 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q237791SPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327537(2-(4-bromophenyl)-N-((2-(thiophen-3-yl)quinolin-3-...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM21680((4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R,16S)-5,9,1...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Mus musculus)
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327524(2-(4-bromophenyl)-N-((2-(furan-3-yl)-7-methoxyquin...)copy SMILEScopy InChI
Affinity DataIC50: 6.10E+3nMAssay Description:Agonist activity at mouse TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327533(2-(4-bromophenyl)-N-((7-chloro-2-(thiophen-3-yl)qu...)copy SMILEScopy InChI
Affinity DataIC50: 6.90E+3nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
TargetG-protein coupled bile acid receptor 1(Mus musculus)
Kalypsys, Inc.

Curated by ChEMBL
LigandPNGBDBM50327526(2-(4-bromophenyl)-N-((7-methoxy-2-phenylquinolin-3...)copy SMILEScopy InChI
Affinity DataIC50: 8.10E+3nMAssay Description:Agonist activity at mouse TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B1HPubMed
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