Compile Data Set for Download or QSAR
Found 94 with Last Name = 'gubler' and Initial = 'u'
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317628(4-{2-(2-Carboxy-ethyl)-3-[6-(3,5-di-pyridin-4-yl-p...)copy SMILEScopy InChI
Affinity DataIC50: 0.0700nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317631(4-{2-(2-Carboxy-ethyl)-3-[6-(3'-fluoro-5-pyridin-4...)copy SMILEScopy InChI
Affinity DataIC50: 0.180nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317632(4-{2-(2-Carboxy-ethyl)-3-[6-(3-pyridin-4-yl-5-thio...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317625(4-{2-(2-Carboxyethyl)-3-[6-([1,1',3,1'']terphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 0.210nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317633(4-{3-[6-(3-Benzo[1,3]dioxol-5-yl-5-pyridin-4-yl-ph...)copy SMILEScopy InChI
Affinity DataIC50: 0.220nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317634(4-{2-(2-Carboxyethyl)-3-[6-(5-thiophen-3-ylbipheny...)copy SMILEScopy InChI
Affinity DataIC50: 0.360nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317635(4-{3-[6-(3-Benzo[1,3]dioxol-5-yl-5-pyrimidin-5-yl-...)copy SMILEScopy InChI
Affinity DataIC50: 0.380nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317636(4-{2-(2-Carboxy-ethyl)-3-[6-(3-pyrimidin-5-yl-5-th...)copy SMILEScopy InChI
Affinity DataIC50: 0.390nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317626(4-{3-[6-(3-5-Benzo[1,3]dioxolyl-5-thiophen-3-ylphe...)copy SMILEScopy InChI
Affinity DataIC50: 0.440nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317624(4-(2-(2-carboxyethyl)-3-(6-(4,6-diphenylpyridin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 0.480nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317637(4-(2-(2-Carboxy-ethyl)-3-{6-[3-(2-chloro-pyridin-4...)copy SMILEScopy InChI
Affinity DataIC50: 0.570nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317638(4-{2-(2-Carboxy-ethyl)-3-[6-(3,5-di-thiophen-3-yl-...)copy SMILEScopy InChI
Affinity DataIC50: 0.580nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317639(4-[3-[6-(5-Benzo[1,3]dioxol-5-yl-biphenyl-3-yloxy)...)copy SMILEScopy InChI
Affinity DataIC50: 0.580nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317630(4-(3-(6-(5-(benzo[d][1,3]dioxol-5-yl)-2'-fluorobip...)copy SMILEScopy InChI
Affinity DataIC50: 0.610nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317623(4-(3-(6-(5-(benzo[d][1,3]dioxol-5-yl)-3'-fluorobip...)copy SMILEScopy InChI
Affinity DataIC50: 1.19nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317641(4-(3-(6-(5-(benzo[d][1,3]dioxol-5-yl)-4'-methoxybi...)copy SMILEScopy InChI
Affinity DataIC50: 3.27nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317642(4-{2-(2-Carboxyethyl)-3-[6-(3,5-dipyrimidin-5-ylph...)copy SMILEScopy InChI
Affinity DataIC50: 5.35nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317643(4-[3-[6-(3,5-Bis-benzo[1,3]dioxol-5-yl-phenoxy)-he...)copy SMILEScopy InChI
Affinity DataIC50: 5.39nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317644(4-{2-(2-Carboxy-ethyl)-3-[6-(4,4''-difluoro-[1.1':...)copy SMILEScopy InChI
Affinity DataIC50: 8.5nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317645(4-(2-(2-Carboxy-ethyl)-3-{6-[3'-fluoro-5-(1H-indol...)copy SMILEScopy InChI
Affinity DataIC50: 14.0nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50223539(CHEMBL33957)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:In vitro inhibition of prostaglandin synthesis was tested in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61NFBPubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317640(4-{2-(2-Carboxy-ethyl)-3-[6-(4,4''-dimethoxy-[1.1'...)copy SMILEScopy InChI
Affinity DataIC50: 31.1nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317625(4-{2-(2-Carboxyethyl)-3-[6-([1,1',3,1'']terphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 38.5nMAssay Description:Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50223541(Clofurac)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:In vitro inhibition of prostaglandin synthesis was tested in ratMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61NFBPubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317627(4-(2-(2-carboxyethyl)-3-(6-(5-(2,3-dihydrobenzo[b]...)copy SMILEScopy InChI
Affinity DataIC50: 60.2nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50223525(CHEMBL35511)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:In vitro inhibition of prostaglandin synthesis was tested in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61NFBPubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317628(4-{2-(2-Carboxy-ethyl)-3-[6-(3,5-di-pyridin-4-yl-p...)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50223523(CHEMBL34264)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:In vitro inhibition of prostaglandin synthesis was tested in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61NFBPubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50223540(CHEMBL34579)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:In vitro inhibition of prostaglandin synthesis was tested in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61NFBPubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50223536(CHEMBL34649)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:In vitro inhibition of prostaglandin synthesis was tested in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61NFBPubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50223535(CHEMBL34410)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:In vitro inhibition of prostaglandin synthesis was tested in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61NFBPubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317626(4-{3-[6-(3-5-Benzo[1,3]dioxolyl-5-thiophen-3-ylphe...)copy SMILEScopy InChI
Affinity DataIC50: 114nMAssay Description:Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317623(4-(3-(6-(5-(benzo[d][1,3]dioxol-5-yl)-3'-fluorobip...)copy SMILEScopy InChI
Affinity DataIC50: 129nMAssay Description:Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317629(4-[3-{6-[3,5-Bis-(2,3-dihydro-benzo[1,4]dioxin-6-y...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317628(4-{2-(2-Carboxy-ethyl)-3-[6-(3,5-di-pyridin-4-yl-p...)copy SMILEScopy InChI
Affinity DataIC50: 143nMAssay Description:Antagonist activity at FLAG-tagged human BLT2 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317626(4-{3-[6-(3-5-Benzo[1,3]dioxolyl-5-thiophen-3-ylphe...)copy SMILEScopy InChI
Affinity DataIC50: 164nMAssay Description:Antagonist activity at FLAG-tagged human BLT2 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetLeukotriene B4 receptor 2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317623(4-(3-(6-(5-(benzo[d][1,3]dioxol-5-yl)-3'-fluorobip...)copy SMILEScopy InChI
Affinity DataIC50: 194nMAssay Description:Antagonist activity at FLAG-tagged human BLT2 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of prostaglandin synthesis was tested in ratMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317624(4-(2-(2-carboxyethyl)-3-(6-(4,6-diphenylpyridin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 205nMAssay Description:Antagonist activity at FLAG-tagged human BLT1 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317628(4-{2-(2-Carboxy-ethyl)-3-[6-(3,5-di-pyridin-4-yl-p...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of CYP2C9 fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50223528(CHEMBL290797)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:In vitro inhibition of prostaglandin synthesis was tested in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61NFBPubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50223532(CHEMBL34698)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:In vitro inhibition of prostaglandin synthesis was tested in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61NFBPubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50223530(CHEMBL285763)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:In vitro inhibition of prostaglandin synthesis was tested in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61NFBPubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM13066(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:In vitro inhibition of prostaglandin synthesis was tested in ratMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317625(4-{2-(2-Carboxyethyl)-3-[6-([1,1',3,1'']terphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 628nMAssay Description:Antagonist activity at FLAG-tagged human BLT2 receptor expressed in HEK293 cells assessed as inhibition of LTB4-stimulated calcium mobilization prein...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50223531(CHEMBL35969)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:In vitro inhibition of prostaglandin synthesis was tested in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61NFBPubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50223522(CHEMBL35313)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:In vitro inhibition of prostaglandin synthesis was tested in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61NFBPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317628(4-{2-(2-Carboxy-ethyl)-3-[6-(3,5-di-pyridin-4-yl-p...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of CYP2C9 by LC/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50223538(CHEMBL35129)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of prostaglandin synthesis was tested in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61NFBPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50317623(4-(3-(6-(5-(benzo[d][1,3]dioxol-5-yl)-3'-fluorobip...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells assessed as reduction of current amplitudeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5G67PubMed
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