Found 85 with Last Name = 'leartsakulpanich' and Initial = 'u' TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 0.0300nM ΔG°: -60.1kJ/mole IC50: 1.82E+3nMpH: 7.0 T: 2°CAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
3D Structure (crystal)TargetBifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N](Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 0.0800nM IC50: 1.52E+3nMAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 0.210nM ΔG°: -55.2kJ/mole IC50: 180nMpH: 7.0 T: 2°CAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 0.310nM ΔG°: -54.3kJ/mole IC50: 360nMpH: 7.0 T: 2°CAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 0.390nM ΔG°: -53.7kJ/mole IC50: 140nMpH: 7.0 T: 2°CAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 0.520nM ΔG°: -53.0kJ/mole IC50: 70nMpH: 7.0 T: 2°CAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 0.530nM ΔG°: -52.9kJ/mole IC50: 800nMpH: 7.0 T: 2°CAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N](Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 0.540nM IC50: 300nMAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 0.630nM ΔG°: -52.5kJ/mole IC50: 2.27E+3nMpH: 7.0 T: 2°CAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 0.690nM ΔG°: -52.3kJ/mole IC50: 200nMpH: 7.0 T: 2°CAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 0.690nM ΔG°: -52.3kJ/mole IC50: 2.12E+3nMpH: 7.0 T: 2°CAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 0.770nM ΔG°: -52.0kJ/mole IC50: 2.38E+3nMpH: 7.0 T: 2°CAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 0.780nM ΔG°: -52.0kJ/mole IC50: 90nMpH: 7.0 T: 2°CAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 0.780nM ΔG°: -52.0kJ/mole IC50: 1.95E+3nMpH: 7.0 T: 2°CAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N](Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 0.810nM IC50: 2.76E+3nMAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Science and Technology Development Agency
Curated by ChEMBL
National Science and Technology Development Agency
Curated by ChEMBL
Affinity DataKi: 0.850nMAssay Description:Inhibition of pyrimethamine-resistant form-2 Plasmodium falciparum N51I, C59R, S108N, I164L, K96N mutant expressed in Escherichia coli BL21(DE3) by M...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N](Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 0.900nM IC50: 3.02E+3nMAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 1.01nM ΔG°: -51.3kJ/mole IC50: 350nMpH: 7.0 T: 2°CAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N](Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 1.05nM IC50: 1.05E+4nMAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 1.14nM ΔG°: -51.0kJ/mole IC50: 1.76E+3nMpH: 7.0 T: 2°CAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N](Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 1.19nM IC50: 1.98E+3nMAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N](Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 1.32nM IC50: 1.39E+4nMAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 1.40nM ΔG°: -50.5kJ/mole IC50: 220nMpH: 7.0 T: 2°CAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N](Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 1.53nM IC50: 1.42E+4nMAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N](Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 2.21nM IC50: 1.24E+4nMAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N](Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 3.04nM IC50: 2.00E+4nMAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 3.42nM ΔG°: -48.3kJ/mole IC50: 1.52E+3nMpH: 7.0 T: 2°CAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 4.18nM ΔG°: -47.8kJ/mole IC50: 1.13E+4nMpH: 7.0 T: 2°CAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 4.29nM ΔG°: -47.8kJ/mole IC50: 2.20E+3nMpH: 7.0 T: 2°CAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N](Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 6.59nM IC50: 3.01E+4nMAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N](Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 7.43nM IC50: 5.00E+4nMAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N](Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 22.5nM IC50: 1.29E+4nMAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N](Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 24.5nM IC50: 5.00E+4nMAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N](Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 28.1nM IC50: 1.82E+4nMAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N](Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 37.8nM IC50: 5.00E+4nMAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N](Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 47.5nM IC50: 5.00E+4nMAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N](Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 63.4nM IC50: 5.00E+4nMAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Science and Technology Development Agency
Curated by ChEMBL
National Science and Technology Development Agency
Curated by ChEMBL
Affinity DataKi: 292nMAssay Description:Inhibition of pyrimethamine-resistant form-2 Plasmodium falciparum N51I, C59R, S108N, I164L, K96N mutant expressed in Escherichia coli BL21(DE3) by M...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase [1-238,S58R,S117N](Plasmodium vivax (malaria parasite P. vivax))
National Center for Genetic Engineering and Biotechnology at Thailand
National Center for Genetic Engineering and Biotechnology at Thailand
Affinity DataKi: 1.08E+3nM IC50: 5.00E+4nMAssay Description:Nineteen Pyr analogs were studied for their inhibition activity against cells expressing either WT or SP21 mutant PvDHFR-TS. The assays were conducte...More data for this Ligand-Target Pair
TargetGlycine hydroxymethyltransferase(Plasmodium falciparum)
Laboratorium f�r Organische Chemie, ETH Zurich , Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland.
Curated by ChEMBL
Laboratorium f�r Organische Chemie, ETH Zurich , Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland.
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of Plasmodium falciparum SHMT using L-serine/(6S)-THF as substrate by methylene tetrahydrofolate dehydrogenase coupled enzyme assayMore data for this Ligand-Target Pair
TargetGlycine hydroxymethyltransferase(Plasmodium falciparum)
Laboratorium f�r Organische Chemie, ETH Zurich , Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland.
Curated by ChEMBL
Laboratorium f�r Organische Chemie, ETH Zurich , Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland.
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of Plasmodium falciparum SHMT using L-serine/(6S)-THF as substrate by methylene tetrahydrofolate dehydrogenase coupled enzyme assayMore data for this Ligand-Target Pair
TargetGlycine hydroxymethyltransferase(Plasmodium falciparum)
Laboratorium f�r Organische Chemie, ETH Zurich , Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland.
Curated by ChEMBL
Laboratorium f�r Organische Chemie, ETH Zurich , Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland.
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibitory activity against Herpes simplex virus type-I specific thymidine kinaseMore data for this Ligand-Target Pair
TargetGlycine hydroxymethyltransferase(Plasmodium falciparum)
Laboratorium f�r Organische Chemie, ETH Zurich , Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland.
Curated by ChEMBL
Laboratorium f�r Organische Chemie, ETH Zurich , Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland.
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of Plasmodium falciparum SHMT using L-serine/(6S)-THF as substrate by methylene tetrahydrofolate dehydrogenase coupled enzyme assayMore data for this Ligand-Target Pair
TargetGlycine hydroxymethyltransferase(Plasmodium falciparum)
Laboratorium f�r Organische Chemie, ETH Zurich , Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland.
Curated by ChEMBL
Laboratorium f�r Organische Chemie, ETH Zurich , Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland.
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of Plasmodium falciparum SHMT using L-serine/(6S)-THF as substrate by methylene tetrahydrofolate dehydrogenase coupled enzyme assayMore data for this Ligand-Target Pair
TargetGlycine hydroxymethyltransferase(Plasmodium falciparum)
Laboratorium f�r Organische Chemie, ETH Zurich , Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland.
Curated by ChEMBL
Laboratorium f�r Organische Chemie, ETH Zurich , Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland.
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of Plasmodium falciparum SHMT using L-serine/(6S)-THF as substrate by methylene tetrahydrofolate dehydrogenase coupled enzyme assayMore data for this Ligand-Target Pair
TargetGlycine hydroxymethyltransferase(Plasmodium falciparum)
Laboratorium f�r Organische Chemie, ETH Zurich , Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland.
Curated by ChEMBL
Laboratorium f�r Organische Chemie, ETH Zurich , Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland.
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of Plasmodium falciparum SHMT using L-serine/(6S)-THF as substrate by methylene tetrahydrofolate dehydrogenase coupled enzyme assayMore data for this Ligand-Target Pair
TargetGlycine hydroxymethyltransferase(Plasmodium falciparum)
Laboratorium f�r Organische Chemie, ETH Zurich , Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland.
Curated by ChEMBL
Laboratorium f�r Organische Chemie, ETH Zurich , Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland.
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of Plasmodium falciparum SHMT using L-serine/(6S)-THF as substrate by methylene tetrahydrofolate dehydrogenase coupled enzyme assayMore data for this Ligand-Target Pair
TargetGlycine hydroxymethyltransferase(Plasmodium falciparum)
Laboratorium f�r Organische Chemie, ETH Zurich , Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland.
Curated by ChEMBL
Laboratorium f�r Organische Chemie, ETH Zurich , Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland.
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Inhibition of Plasmodium falciparum SHMT using L-serine/(6S)-THF as substrate by methylene tetrahydrofolate dehydrogenase coupled enzyme assayMore data for this Ligand-Target Pair
TargetGlycine hydroxymethyltransferase(Plasmodium falciparum)
Laboratorium f�r Organische Chemie, ETH Zurich , Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland.
Curated by ChEMBL
Laboratorium f�r Organische Chemie, ETH Zurich , Vladimir-Prelog-Weg 3, 8093 Zurich, Switzerland.
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of Plasmodium falciparum SHMT using L-serine/(6S)-THF as substrate by methylene tetrahydrofolate dehydrogenase coupled enzyme assayMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium falciparum (isolate K1 / Thailand))
National Science and Technology Development Agency
Curated by ChEMBL
National Science and Technology Development Agency
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of pyrimethamine-resistant form-2 Plasmodium falciparum N51I, C59R, S108N, I164L, K96N mutant expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
