Compile Data Set for Download or QSAR
Found 163 with Last Name = 'meyer' and Initial = 'u'
TargetMineralocorticoid receptor(Homo sapiens (Human))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM21725((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...)copy SMILEScopy InChI
Affinity DataKi:  37nMAssay Description:Inhibitory concentration against Mineralocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8DKVPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM50226465(CHEMBL402063 | E-guggulsterone | pregna-4,17(20)-c...)copy SMILEScopy InChI
Affinity DataKi:  39nMAssay Description:Inhibitory concentration against Mineralocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8DKVPubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)copy SMILEScopy InChI
Affinity DataKi:  160nMAssay Description:Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN74RRPubMed
TargetProgesterone receptor(Homo sapiens (Human))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM50226465(CHEMBL402063 | E-guggulsterone | pregna-4,17(20)-c...)copy SMILEScopy InChI
Affinity DataKi:  201nMAssay Description:Inhibitory concentration against Progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8DKVPubMed
TargetProgesterone receptor(Homo sapiens (Human))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM21725((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...)copy SMILEScopy InChI
Affinity DataKi:  224nMAssay Description:Inhibitory concentration against Progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8DKVPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM50226465(CHEMBL402063 | E-guggulsterone | pregna-4,17(20)-c...)copy SMILEScopy InChI
Affinity DataKi:  224nMAssay Description:Inhibitory concentration against Glucorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8DKVPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM50226465(CHEMBL402063 | E-guggulsterone | pregna-4,17(20)-c...)copy SMILEScopy InChI
Affinity DataKi:  240nMAssay Description:Inhibitory concentration against Androgen receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8DKVPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM21725((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...)copy SMILEScopy InChI
Affinity DataKi:  252nMAssay Description:Inhibitory concentration against Glucorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8DKVPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM21725((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...)copy SMILEScopy InChI
Affinity DataKi:  315nMAssay Description:Inhibitory concentration against Androgen receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8DKVPubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM50007548((S)-2-Amino-4-phosphono-butyric acid | (S)-2-amino...)copy SMILEScopy InChI
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of [3H]LY341495 from rat recombinant mGluR8 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)copy SMILEScopy InChI
Affinity DataKi:  3.40E+3nMAssay Description:Displacement of [3H]LY341495 from rat recombinant mGluR8 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN74RRPubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM17657((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...)copy SMILEScopy InChI
Affinity DataKi:  3.40E+3nMAssay Description:Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN74RRPubMed
TargetBile acid receptor(Homo sapiens (Human))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM21725((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+3nMAssay Description:Inhibitory concentration against Farnesoid X receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8DKVPubMed
TargetBile acid receptor(Homo sapiens (Human))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM50226465(CHEMBL402063 | E-guggulsterone | pregna-4,17(20)-c...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+3nMAssay Description:Inhibitory concentration against Farnesoid X receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8DKVPubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM50207814((2S,1'R,2'S)-2-(2'-phosphonocyclopropyl)glycine | ...)copy SMILEScopy InChI
Affinity DataKi:  7.40E+3nMAssay Description:Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN74RRPubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM50207811((2S,1'R,2'S,3'R)-2-(2'-phosphono-3'-phenylcyclopro...)copy SMILEScopy InChI
Affinity DataKi:  2.40E+4nMAssay Description:Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN74RRPubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM50207814((2S,1'R,2'S)-2-(2'-phosphonocyclopropyl)glycine | ...)copy SMILEScopy InChI
Affinity DataKi:  6.30E+4nMAssay Description:Displacement of [3H]LY341495 from rat recombinant mGluR8 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN74RRPubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM50207811((2S,1'R,2'S,3'R)-2-(2'-phosphono-3'-phenylcyclopro...)copy SMILEScopy InChI
Affinity DataKi:  1.30E+5nMAssay Description:Displacement of [3H]LY341495 from rat recombinant mGluR8 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN74RRPubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM50207812((2S,1'R,2'S,3'S)-2-(2'-phosphono-3'-phenylcyclopro...)copy SMILEScopy InChI
Affinity DataKi:  1.90E+5nMAssay Description:Displacement of [3H]LY341495 from rat recombinant mGluR8 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN74RRPubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM50207812((2S,1'R,2'S,3'S)-2-(2'-phosphono-3'-phenylcyclopro...)copy SMILEScopy InChI
Affinity DataKi:  6.30E+5nMAssay Description:Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN74RRPubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM50207813((2S,1'S,2'R,3'S)-2-(2'-phosphono-3'-phenylcyclopro...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN74RRPubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM50207810((2S,1'S,2'R,3'R)-2-(2'-phosphono-3'-phenylcyclopro...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]L-AP4 from rat recombinant mGluR4 expressed in BHK cells by SPA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN74RRPubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM21725((1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethy...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibitory concentration against Pregnane X receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8DKVPubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Universit£ di Perugia

Curated by ChEMBL
LigandPNGBDBM50226465(CHEMBL402063 | E-guggulsterone | pregna-4,17(20)-c...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibitory concentration against Pregnane X receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8DKVPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50231755(6,6-dimethyl-2-phenylethynyl-7,8-dihydro-6H-quinol...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD20B8PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50443088(CHEMBL3087216)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37XRDPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50438277(CHEMBL2408412)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD20B8PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50443089(CHEMBL3086715)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37XRDPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50443089(CHEMBL3086715)copy SMILEScopy InChI
Affinity DataIC50: 28.4nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37XRDPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50438295(CHEMBL2408568)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD20B8PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50443090(CHEMBL3086712)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37XRDPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50438289(CHEMBL2408574)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD20B8PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50443091(CHEMBL3087511)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37XRDPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50443092(CHEMBL3085792)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37XRDPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50443093(CHEMBL3087217)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37XRDPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50443087(CHEMBL3087214)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37XRDPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50443086(CHEMBL3087508)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37XRDPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50438278(CHEMBL2408411)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD20B8PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50443084(CHEMBL3087220)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37XRDPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50443085(AFQ056 | Mavoglurant)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50443083(CHEMBL3087219)copy SMILEScopy InChI
Affinity DataIC50: 76nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37XRDPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50438294(CHEMBL2408569)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD20B8PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50438298(CHEMBL2408565)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD20B8PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50443082(CHEMBL3087513)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37XRDPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50443081(CHEMBL3087212)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37XRDPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50443080(CHEMBL3087514)copy SMILEScopy InChI
Affinity DataIC50: 103nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37XRDPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50443080(CHEMBL3087514)copy SMILEScopy InChI
Affinity DataIC50: 103nMAssay Description:Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37XRDPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50438288(CHEMBL2408575)copy SMILEScopy InChI
Affinity DataIC50: 111nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD20B8PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50438305(CHEMBL2408585)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD20B8PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merz Pharmaceuticals GmbH

Curated by ChEMBL
LigandPNGBDBM50438291(CHEMBL2408572)copy SMILEScopy InChI
Affinity DataIC50: 125nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD20B8PubMed
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