Compile Data Set for Download or QSAR
Found 136 with Last Name = 'ohto' and Initial = 'u'
TargetBeta-galactosidase [24-677,R201C](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM228800(NOEV | Sapienic acid (SpA))copy SMILEScopy InChI
Affinity DataKi:  940nM ΔG°:  -35.8kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2NW4PubMed
TargetBeta-galactosidase [24-677](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM228800(NOEV | Sapienic acid (SpA))copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nM ΔG°:  -35.4kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2NW4PubMed
TargetBeta-galactosidase [24-677,I51T](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM228800(NOEV | Sapienic acid (SpA))copy SMILEScopy InChI
Affinity DataKi:  1.20E+3nM ΔG°:  -35.2kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2NW4PubMed
TargetBeta-galactosidase [24-677,I51T](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM50163440((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)copy SMILEScopy InChI
Affinity DataKi:  4.47E+4nM ΔG°:  -25.8kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
TargetBeta-galactosidase [24-677,R201C](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM50163440((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)copy SMILEScopy InChI
Affinity DataKi:  4.90E+4nM ΔG°:  -25.6kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
TargetBeta-galactosidase [24-677,R201C](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM228802(5N,6S-(N'-butyliminomethylidene)-6-thio-1-deox...)copy SMILEScopy InChI
Affinity DataKi:  5.33E+4nM ΔG°:  -25.4kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBeta-galactosidase [24-677](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM50163440((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)copy SMILEScopy InChI
Affinity DataKi:  6.18E+4nM ΔG°:  -25.0kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
TargetBeta-galactosidase [24-677](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM228802(5N,6S-(N'-butyliminomethylidene)-6-thio-1-deox...)copy SMILEScopy InChI
Affinity DataKi:  6.83E+4nM ΔG°:  -24.7kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBeta-galactosidase [24-677,I51T](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM228802(5N,6S-(N'-butyliminomethylidene)-6-thio-1-deox...)copy SMILEScopy InChI
Affinity DataKi:  6.88E+4nM ΔG°:  -24.7kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBeta-galactosidase [24-677](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM228803(5N,6S-(N'-butyliminomethylidene)-6-thiogalacto...)copy SMILEScopy InChI
Affinity DataKi:  2.53E+5nM ΔG°:  -21.4kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2NW4PubMed
TargetBeta-galactosidase [24-677,I51T](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM228803(5N,6S-(N'-butyliminomethylidene)-6-thiogalacto...)copy SMILEScopy InChI
Affinity DataKi:  3.20E+5nM ΔG°:  -20.8kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2NW4PubMed
TargetBeta-galactosidase [24-677,R201C](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM228803(5N,6S-(N'-butyliminomethylidene)-6-thiogalacto...)copy SMILEScopy InChI
Affinity DataKi:  3.20E+5nM ΔG°:  -20.7kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2NW4PubMed
TargetBeta-galactosidase [24-677,I51T](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM228804(N-(N'-butylthiocarbamoyl)-1-deoxygalactonojiri...)copy SMILEScopy InChI
Affinity DataKi:  3.29E+5nM ΔG°:  -20.7kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2NW4PubMed
TargetBeta-galactosidase [24-677](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM228804(N-(N'-butylthiocarbamoyl)-1-deoxygalactonojiri...)copy SMILEScopy InChI
Affinity DataKi:  3.73E+5nM ΔG°:  -20.4kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2NW4PubMed
TargetBeta-galactosidase [24-677,R201C](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM228804(N-(N'-butylthiocarbamoyl)-1-deoxygalactonojiri...)copy SMILEScopy InChI
Affinity DataKi:  3.88E+5nM ΔG°:  -20.3kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2NW4PubMed
TargetBeta-galactosidase [24-677](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM228805(Galactose)copy SMILEScopy InChI
Affinity DataKi:  4.14E+6nM ΔG°:  -14.1kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2NW4PubMed
TargetBeta-galactosidase [24-677,I51T](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM228805(Galactose)copy SMILEScopy InChI
Affinity DataKi:  4.91E+6nM ΔG°:  -13.7kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2NW4PubMed
TargetBeta-galactosidase [24-677,R201C](Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM228805(Galactose)copy SMILEScopy InChI
Affinity DataKi:  5.61E+6nM ΔG°:  -13.4kJ/molepH: 4.5 T: 2°CAssay Description:β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2NW4PubMed
TargetToll-like receptor 8(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514792(CHEMBL4519240)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetToll-like receptor 8(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514792(CHEMBL4519240)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of ssRNA06-induced NF-kappaB activation measured after 24 hrs by quanti-b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetToll-like receptor 8(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514809(CHEMBL4530243)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NMGPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514806(CHEMBL4452260)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NMGPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514804(CHEMBL4461378)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NMGPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514805(CHEMBL4539893)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NMGPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514797(CHEMBL4451165)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NMGPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514813(CHEMBL4471285)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NMGPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514807(CHEMBL4590994)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NMGPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514796(CHEMBL4535822)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NMGPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514818(CHEMBL4585768)copy SMILEScopy InChI
Affinity DataIC50: 520nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NMGPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514811(CHEMBL4564658)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NMGPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514799(CHEMBL4445770)copy SMILEScopy InChI
Affinity DataIC50: 590nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NMGPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514816(CHEMBL4468868)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NMGPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514800(CHEMBL4449343)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NMGPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514819(CHEMBL4446241)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NMGPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514821(CHEMBL4451720)copy SMILEScopy InChI
Affinity DataIC50: 980nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NMGPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514820(CHEMBL4437576)copy SMILEScopy InChI
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NMGPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514801(CHEMBL4473196)copy SMILEScopy InChI
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NMGPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514794(CHEMBL4519304)copy SMILEScopy InChI
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NMGPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514812(CHEMBL4564959)copy SMILEScopy InChI
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NMGPubMed
TargetToll-like receptor 4(Homo sapiens (Human))TBA
LigandPNGBDBM50563780(CHEMBL4795714)copy SMILES
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR4 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as assessed as inhibition of LPS-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5Z3FPubMed
TargetToll-like receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM50563780(CHEMBL4795714)copy SMILES
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR7 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as assessed as inhibition of imid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5Z3FPubMed
TargetToll-like receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50563780(CHEMBL4795714)copy SMILES
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR2 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as inhibition of Pam2CS-induced N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5Z3FPubMed
TargetToll-like receptor 9(Homo sapiens (Human))TBA
LigandPNGBDBM50563780(CHEMBL4795714)copy SMILES
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR9 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as assessed as inhibition of ODN2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5Z3FPubMed
TargetToll-like receptor 3(Homo sapiens)TBA
LigandPNGBDBM50563780(CHEMBL4795714)copy SMILES
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR3 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as assessed as inhibition of poly...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5Z3FPubMed
TargetToll-like receptor 5(Homo sapiens)TBA
LigandPNGBDBM50563780(CHEMBL4795714)copy SMILES
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human TLR5 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as assessed as inhibition of flag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5Z3FPubMed
TargetToll-like receptor 8(Homo sapiens (Human))
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50514814(CHEMBL4437700)copy SMILEScopy InChI
Affinity DataIC50: 2.81E+3nMAssay Description:Inhibition of human TLR8 expressed in HEK-Blue cells assessed as inhibition of R848-induced NF-kappaB activation measured after 24 hrs by quanti-blue...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9NMGPubMed
LigandPNGBDBM50563780(CHEMBL4795714)copy SMILES
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK1delta using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5Z3FPubMed
LigandPNGBDBM50563780(CHEMBL4795714)copy SMILES
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK1gamma using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric h...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5Z3FPubMed
LigandPNGBDBM50563780(CHEMBL4795714)copy SMILES
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK1beta using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric ho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5Z3FPubMed
LigandPNGBDBM50563780(CHEMBL4795714)copy SMILES
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of wild-type human CAMK2beta using KKALRRQETVDAL peptide as substrate in presence of Ca2+ calmodulin and [gamma-33P]-ATP by radiometric ho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5Z3FPubMed
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