Compile Data Set for Download or QSAR
Found 29 with Last Name = 'soumyanarayanan' and Initial = 'u'
TargetHistone deacetylase 6(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50504583(CHEMBL4444554)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human HDAC6 using Arg-His-Lys-Lys (Ac) as substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human HDAC6 using Arg-His-Lys-Lys (Ac) as substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50504581(CHEMBL4554522)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human HDAC6 using Arg-His-Lys-Lys (Ac) as substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50504582(CHEMBL4438378)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human HDAC6 using Arg-His-Lys-Lys (Ac) as substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human HDAC1 using Arg-His-Lys-Lys (Ac) as substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50504580(CHEMBL4551593)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human HDAC6 using Arg-His-Lys-Lys (Ac) as substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50504584(CHEMBL4461884)copy SMILEScopy InChI
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human HDAC6 using Arg-His-Lys-Lys (Ac) as substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50353128(CHEMBL1231795)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human HDAC6 using Arg-His-Lys-Lys (Ac) as substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMedDrugBank
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50353128(CHEMBL1231795)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human G9a using core histone H3 as substrate incubated for 1 hr in presence of [3H]-SAM by filter binding methodMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50504581(CHEMBL4554522)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of human HDAC3 using Arg-His-Lys-Lys (Ac) as substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50504579(CHEMBL4572459)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of human HDAC6 using Arg-His-Lys-Lys (Ac) as substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50300028(CHEMBL569864 | N-(1-benzylpiperidin-4-yl)-6,7-dime...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50504582(CHEMBL4438378)copy SMILEScopy InChI
Affinity DataIC50: 233nMAssay Description:Inhibition of human HDAC1 using Arg-His-Lys-Lys (Ac) as substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 306nMAssay Description:Inhibition of human HDAC1 using Arg-His-Lys-Lys (Ac) as substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50504581(CHEMBL4554522)copy SMILEScopy InChI
Affinity DataIC50: 896nMAssay Description:Inhibition of human HDAC1 using Arg-His-Lys-Lys (Ac) as substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50504583(CHEMBL4444554)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of human HDAC1 using Arg-His-Lys-Lys (Ac) as substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50504581(CHEMBL4554522)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of human HDAC2 using Arg-His-Lys-Lys (Ac) as substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50504581(CHEMBL4554522)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human HDAC8 using Arg-His-Lys (Ac)-Lys (Ac) as substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50504581(CHEMBL4554522)copy SMILEScopy InChI
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of human HDAC11 using Acetyl-Lys (trifluoroacetyl)-AMC) as substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50300028(CHEMBL569864 | N-(1-benzylpiperidin-4-yl)-6,7-dime...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human G9a using core histone H3 as substrate incubated for 1 hr in presence of [3H]-SAM by filter binding methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50504580(CHEMBL4551593)copy SMILEScopy InChI
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of human HDAC1 using Arg-His-Lys-Lys (Ac) as substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50504581(CHEMBL4554522)copy SMILEScopy InChI
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of human HDAC10 using Acetyl-Lys (trifluoroacetyl)-AMC) as substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50504579(CHEMBL4572459)copy SMILEScopy InChI
Affinity DataIC50: 3.08E+3nMAssay Description:Inhibition of human HDAC1 using Arg-His-Lys-Lys (Ac) as substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50504584(CHEMBL4461884)copy SMILEScopy InChI
Affinity DataIC50: 3.37E+3nMAssay Description:Inhibition of human HDAC1 using Arg-His-Lys-Lys (Ac) as substrate incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50504581(CHEMBL4554522)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human DNMT1 using Poly(dI-dC) as substrate incubated for 1 hr in presence of [3H]-SAM by filter binding methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50504581(CHEMBL4554522)copy SMILEScopy InChI
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of human DNMT3a using lambda DNA as substrate incubated for 1 hr in presence of [3H]-SAM by filter binding methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50504581(CHEMBL4554522)copy SMILEScopy InChI
Affinity DataEC50:  1.42E+5nMAssay Description:Inhibition of human G9a using core histone H3 (1 to 21 residues) as substrate incubated for 1 hr in presence of [3H]-SAM by filter binding methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed
TargetHistone deacetylase 1/2/3(Homo sapiens (Human))
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50504581(CHEMBL4554522)copy SMILEScopy InChI
Affinity DataEC50:  7.50E+3nMAssay Description:Inhibition of HDAC1/2/3 in human KMS-12-BM cells assessed as increase in Ac-H3 level incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZS30T4PubMed