Compile Data Set for Download or QSAR
Found 112 with Last Name = 'guillaume' and Initial = 'v'
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50427703(CHEMBL2324220)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:Inhibition of human recombinant IDE expressed in CHO cells in presence of [125I]-insulin by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5ZT5PubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50525490(CHEMBL4437643)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant IDE exosite (unknown origin) expressed in Escherichia coli using insulin as substrate incubated for 4 hrs by AlphaLisa assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant IDE expressed in Escherichia coli BL21 (DE3) cells using insulin as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5ZT5PubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant IDE expressed in Escherichia coli BL21 (DE3) cells using ATTO 655- Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5ZT5PubMed
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50525489(CHEMBL4556893)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminal His6-tagged mouse recombinant IDE Escherichia coli BL21 (DE3) cells using fluorogenic peptide Mca-RPPGFSAFK(Dnp)-OH as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5ZT5PubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50462574(CHEMBL4241044)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of human recombinant IDE expressed in Escherichia coli BL21 (DE3) cells using insulin as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50462574(CHEMBL4241044)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of wild type human IDE catalytic site using insulin as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50005641(CHEMBL3235416)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of IDE exosite and catalytic site (unknown origin)More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50462574(CHEMBL4241044)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant IDE harboring C110L/C171S/C178A/C257V/C414L/C573N/C590S/C789S/C812A/C819A/C904S/C966N/C974A mutant expressed in Esche...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661074((S)-N-hydroxy-2-(4-((5-(pyridin-2-yl)thiophene-2-s...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661075((S)-N-hydroxy-2-(4-((5-phenylthiophene-2-sulfonami...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661076((S)-N-hydroxy-3-(4-phenoxyphenyl)-2-(4-((5-(pyridi...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661077((S)-N-hydroxy-3-(4-methoxyphenyl)-2-(4-((5-phenylt...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661078((S)-N-hydroxy-3-(4-methoxyphenyl)-2-(4-((5-(pyridi...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661079((2S)-3-(4-tert-butoxyphenyl)-2-[4-[(5-phenyl-2-thi...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661080((2S)-3-(4-tert-butoxyphenyl)-2-[4-[[[5-(2-pyridyl)...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661081((S)-4-(5-(N-((1-(1-(hydroxyamino)-3-(4-methoxyphen...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661082((S)-N-hydroxy-3-(4-hydroxyphenyl)-2-(4-((5-(pyridi...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661090((2S)-3-(4-methoxyphenyl)-2-[4-[[[5-(4-pyridyl)-2-t...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661091((2S)-3-(1,3-benzodioxol-5-yl)-2-[4-[[[5-(2-pyridyl...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661092((2S)-3-(4-methoxyphenyl)-2-[4-[[[5-(3-pyridyl)-2-t...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661093((2S)-3-(3-chloro-4-hydroxy-phenyl)-2-[4-[[[5-(2-py...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661094((2S)-3-(3-chloro-4-hydroxy-phenyl)-2-[4-[[(5-pheny...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661095((2S)-3-(3,4-dimethoxyphenyl)-2-[4-[[[5-(2-pyridyl)...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661096((2S)-3-(3,4-dimethoxyphenyl)-2-[4-[[(5-phenyl-2-th...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661097(3-[5-[[1-[(1S)-2-(hydroxyamino)-1-[(4-methoxypheny...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661098((2S)-3-(3-fluoro-4-hydroxy-phenyl)-2-[4-[[[5-(2-py...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661099((2S)-3-(3-fluoro-4-hydroxy-phenyl)-2-[4-[[(5-pheny...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661100((2S)-3-(4-methoxyphenyl)-2-[4-[[methyl-[[5-(2-pyri...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661101((2S)-3-(4-methoxyphenyl)-2-[4-[(1S)-1-[[5-(2-pyrid...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661103((2S)-3-(3-methoxyphenyl)-2-[4-[[[5-(2-pyridyl)-2-t...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661105((2S)-3-[4-(2-methoxyethoxy)phenyl]-2-[4-[[[5-(2-py...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661106((2S)-3-(3-fluoro-4-methoxy-phenyl)-2-[4-[[[5-(2-py...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661107((2S)-3-(3-chloro-4-methoxy-phenyl)-2-[4-[[[5-(2-py...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661108((2S)-3-(4-ethynylphenyl)-2-[4-[[(5-phenyl-2-thieny...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661109((2S)-3-[4-(N-hydroxycarbamimidoyl)phenyl]-2-[4-[[(...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661110((2)-3-(4-methoxyphenyl)-2-[4-[[(2-phenylthiazol-5-...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661114((2S)-3-(4-cyanophenyl)-2-[4-[[(5-phenyl-2-thienyl)...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))TBA
LigandPNGBDBM661096((2S)-3-(3,4-dimethoxyphenyl)-2-[4-[[(5-phenyl-2-th...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))TBA
LigandPNGBDBM661070((2S)-3-(4-hydroxyphenyl)-2-[4-[(3-thienylsulfonyla...)
Affinity DataIC50: 5.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))TBA
LigandPNGBDBM661093((2S)-3-(3-chloro-4-hydroxy-phenyl)-2-[4-[[[5-(2-py...)
Affinity DataIC50: 5.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))TBA
LigandPNGBDBM661072((2S)-3-(4-hydroxyphenyl)-2-[4-[[[5-(2-pyridyl)-2-t...)
Affinity DataIC50: 5.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 2(Homo sapiens (Human))TBA
LigandPNGBDBM661095((2S)-3-(3,4-dimethoxyphenyl)-2-[4-[[[5-(2-pyridyl)...)
Affinity DataIC50: 5.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661054((R)-N-hydroxy-4-(1H-indol-3-yl)-3-(4-((5-phenylthi...)
Affinity DataIC50: 5.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661055((R)-N-hydroxy-3-(1H-indol-3-yl)-2-(4-((5-phenylthi...)
Affinity DataIC50: 5.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661056((S)-N-hydroxy-3-(1H-indol-3-yl)-2-(4-((N-methyl-5-...)
Affinity DataIC50: 5.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661057((S)-N-hydroxy-3-(1H-indol-3-yl)-2-(4-((5-phenylthi...)
Affinity DataIC50: 5.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661058((S)-2-(4-((5-bromothiophene-2-sulfonamido)methyl)-...)
Affinity DataIC50: 5.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661059((R)-N-hydroxy-4-(naphthalen-2-yl)-3-(4-((5-phenylt...)
Affinity DataIC50: 5.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetEndoplasmic reticulum aminopeptidase 1 (ERAP1)(Homo sapiens (Human))TBA
LigandPNGBDBM661060((S)-N-hydroxy-4-(4-hydroxyphenyl)-3-(4-((N-methyl-...)
Affinity DataIC50: 5.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
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