Compile Data Set for Download or QSAR
Found 163 with Last Name = 'landry' and Initial = 'v'
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50427703(CHEMBL2324220)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:Inhibition of human recombinant IDE expressed in CHO cells in presence of [125I]-insulin by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5ZT5PubMed
TargetNeprilysin(Homo sapiens (Human))
INSERM

Curated by ChEMBL
LigandPNGBDBM21641(2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human NEP-mediated amyloid beta hydrolysisMore data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50525490(CHEMBL4437643)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant IDE exosite (unknown origin) expressed in Escherichia coli using insulin as substrate incubated for 4 hrs by AlphaLisa assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
INSERM

Curated by ChEMBL
LigandPNGBDBM21642((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human ACE-mediated amyloid beta hydrolysisMore data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant IDE expressed in Escherichia coli BL21 (DE3) cells using insulin as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5ZT5PubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM34233(2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-ben...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant IDE expressed in Escherichia coli BL21 (DE3) cells using ATTO 655- Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5ZT5PubMed
TargetInsulin-degrading enzyme(Mus musculus (Mouse))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50525489(CHEMBL4556893)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of N-terminal His6-tagged mouse recombinant IDE Escherichia coli BL21 (DE3) cells using fluorogenic peptide Mca-RPPGFSAFK(Dnp)-OH as subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5ZT5PubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50462574(CHEMBL4241044)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Inhibition of human recombinant IDE expressed in Escherichia coli BL21 (DE3) cells using insulin as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50462574(CHEMBL4241044)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of wild type human IDE catalytic site using insulin as substrate preincubated for 10 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50005641(CHEMBL3235416)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50005641(CHEMBL3235416)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of IDE exosite and catalytic site (unknown origin)More data for this Ligand-Target Pair
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50462574(CHEMBL4241044)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant IDE harboring C110L/C171S/C178A/C257V/C414L/C573N/C590S/C789S/C812A/C819A/C904S/C966N/C974A mutant expressed in Esche...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50087157(5-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50005638(CHEMBL3235414)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1M34PubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50005640(CHEMBL3235415)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1M34PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096063(6-(5-Hydroxy-3-{5-[3-(4-methyl-piperazin-1-yl)-pro...)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096043(5-(3-Methyl-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50005637(CHEMBL3235413)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1M34PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096064(5-(3-Methyl-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096024(6-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096061(6-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096076(5-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096012(6-(3-Methyl-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096023(3-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096059(4-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096021(6-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096017(4-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096078(4-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096075(5-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096048(6-(3-Methyl-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
LigandPNGBDBM50265021(3-(benzyl(hydroxy)amino)-4-(4-butoxyphenylamino)cy...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8KV6PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096051(3-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096052(3-(3-Methyl-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096036(3-(8-Hydroxy-3-methyl-1,4-dioxo-1,4-dihydro-naphth...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50005636(CHEMBL3235412)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1M34PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096056(5-Hydroxy-2,3-bis-[6-(4-methyl-piperazin-1-yl)-6-o...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50005641(CHEMBL3235416)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (1 to 40) hydrolysis preincubated for 10 mins measured after 30 mins by spectrophotometer a...More data for this Ligand-Target Pair
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096047(6-(3-Methyl-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096040(3-(3-Methyl-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096025(4-(3-Methyl-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096069(4-(3-Methyl-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096010(3-(3-Methyl-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096011(5-Hydroxy-2,3-bis-[5-(4-methyl-piperazin-1-yl)-5-o...)copy SMILEScopy InChI
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096044(2-{3-[4-(3-Amino-propyl)-piperazin-1-yl]-propylami...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
LigandPNGBDBM50329003(CHEMBL1270566 | potassium 4-(3-(1H-imidazol-1-yl)p...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of ADAMTS-5 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057G51PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096079(5-(5-Hydroxy-3-{4-[3-(4-methyl-piperazin-1-yl)-pro...)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096042(2-methyl-3-(3-{4-[3-(3-methyl-1,4-dioxo-1,4-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
TargetInsulin-degrading enzyme(Homo sapiens (Human))
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50350471(CEFMETAZOLE)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human recombinant IDE expressed in Escherichia coli BL21 (DE3) cells using ATTO 655- Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS5ZT5PubMed
LigandPNGBDBM50328999(CHEMBL1270372 | potassium 4-(3-phenylpropyl)-5-((3...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of ADAMTS-4 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057G51PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
UMR 8525 CNRS - Université Lille II

Curated by ChEMBL
LigandPNGBDBM50096039(2-{3-[4-(3-Amino-propyl)-piperazin-1-yl]-propylami...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibitory activity against Trypanosoma cruzi trypanothione disulfide reductase, assay in presence of 57 microM T(S)2.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MC8Z7RPubMed
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