Compile Data Set for Download or QSAR
Found 10 with Last Name = 'manaves' and Initial = 'v'
TargetHistone-lysine N-methyltransferase KMT5B(Homo sapiens (Human))
AbbVie

LigandPNGBDBM223981(6,7-Dichloro-N-cyclopentyl-4-(pyridin-4-yl)phthala...)copy SMILEScopy InChI
Affinity DataIC50: 25nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase KMT5C(Homo sapiens (Human))
AbbVie

LigandPNGBDBM223981(6,7-Dichloro-N-cyclopentyl-4-(pyridin-4-yl)phthala...)copy SMILEScopy InChI
Affinity DataIC50: 144nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X065XFPubMed
TargetHistone-lysine N-methyltransferase KMT5B(Homo sapiens (Human))
AbbVie

LigandPNGBDBM223980(6,7-Dichloro-N-cyclopentylquinolin-4-amine (2))copy SMILEScopy InChI
Affinity DataIC50: 590nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X065XFPubMed
TargetHistone-lysine N-methyltransferase KMT5C(Homo sapiens (Human))
AbbVie

LigandPNGBDBM223980(6,7-Dichloro-N-cyclopentylquinolin-4-amine (2))copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X065XFPubMed
TargetHistone-lysine N-methyltransferase KMT5C(Homo sapiens (Human))
AbbVie

LigandPNGBDBM223979(7-Chloro-N-cyclopentylquinolin-4-amine (1))copy SMILEScopy InChI
Affinity DataIC50: 4.80E+3nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X065XFPubMed
TargetHistone-lysine N-methyltransferase KMT5B(Homo sapiens (Human))
AbbVie

LigandPNGBDBM223979(7-Chloro-N-cyclopentylquinolin-4-amine (1))copy SMILEScopy InChI
Affinity DataIC50: 5.90E+3nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X065XFPubMed
TargetHistone-lysine N-methyltransferase KMT5B(Homo sapiens (Human))
AbbVie

LigandPNGBDBM223982((6,7-Dichloro-4-(cyclopentylamino)phthalazin-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X065XFPubMed
TargetHistone-lysine N-methyltransferase KMT5C(Homo sapiens (Human))
AbbVie

LigandPNGBDBM223982((6,7-Dichloro-4-(cyclopentylamino)phthalazin-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X065XFPubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))TBA
LigandPNGBDBM50467836(CHEMBL4282264)copy SMILEScopy InChI
Affinity DataKd:  0.00128nMAssay Description:Binding affinity to human Biotin-Avi-P300 assessed as dissociation constant using Neutravidin as ligand measured by Surface Plasmon Resonance methodMore data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Homo sapiens (Human))TBA
LigandPNGBDBM50467836(CHEMBL4282264)copy SMILEScopy InChI
Affinity DataKd:  1.40nMAssay Description:Binding affinity to human Biotin-Avi-P300 using Neutravidin as ligand measured by Surface Plasmon Resonance methodMore data for this Ligand-Target Pair