Compile Data Set for Download or QSAR
Found 76 with Last Name = 'pathade' and Initial = 'v'
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM50380754(CHEMBL2017853)copy SMILEScopy InChI
Affinity DataKi:  300nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli using para-nitrophenyl phosphate as substrate preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53ZSPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM50380753(CHEMBL2017852)copy SMILEScopy InChI
Affinity DataKi:  400nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli using para-nitrophenyl phosphate as substrate preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53ZSPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM50380756(CHEMBL2017855)copy SMILEScopy InChI
Affinity DataKi:  500nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli using para-nitrophenyl phosphate as substrate preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53ZSPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM50380755(CHEMBL2017854)copy SMILEScopy InChI
Affinity DataKi:  500nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli using para-nitrophenyl phosphate as substrate preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53ZSPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM50380751(CHEMBL2017850)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli using para-nitrophenyl phosphate as substrate preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53ZSPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM50380749(CHEMBL2017848)copy SMILEScopy InChI
Affinity DataKi:  800nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli using para-nitrophenyl phosphate as substrate preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53ZSPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM50380738(CHEMBL2017836)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli using para-nitrophenyl phosphate as substrate preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53ZSPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM50380741(CHEMBL2017840)copy SMILEScopy InChI
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli using para-nitrophenyl phosphate as substrate preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53ZSPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM50380748(CHEMBL2017847)copy SMILEScopy InChI
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli using para-nitrophenyl phosphate as substrate preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53ZSPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM50380747(CHEMBL2017846)copy SMILEScopy InChI
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli using para-nitrophenyl phosphate as substrate preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53ZSPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM50380750(CHEMBL2017849)copy SMILEScopy InChI
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli using para-nitrophenyl phosphate as substrate preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53ZSPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM50380746(CHEMBL2017845)copy SMILEScopy InChI
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli using para-nitrophenyl phosphate as substrate preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53ZSPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM50380742(CHEMBL2017841)copy SMILEScopy InChI
Affinity DataKi:  2.90E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli using para-nitrophenyl phosphate as substrate preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53ZSPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM50380752(CHEMBL2017851)copy SMILEScopy InChI
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli using para-nitrophenyl phosphate as substrate preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53ZSPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM50380744(CHEMBL2017843)copy SMILEScopy InChI
Affinity DataKi:  5.10E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli using para-nitrophenyl phosphate as substrate preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53ZSPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM13990(5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-(methoxycarbony...)copy SMILEScopy InChI
Affinity DataKi:  6.90E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli using para-nitrophenyl phosphate as substrate preincubated for 30 mins followed b...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM50380743(CHEMBL2017842)copy SMILEScopy InChI
Affinity DataKi:  7.70E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli using para-nitrophenyl phosphate as substrate preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53ZSPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM50380740(CHEMBL2017839)copy SMILEScopy InChI
Affinity DataKi:  7.80E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli using para-nitrophenyl phosphate as substrate preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53ZSPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM50380737(CHEMBL2017838)copy SMILEScopy InChI
Affinity DataKi:  7.80E+3nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli using para-nitrophenyl phosphate as substrate preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53ZSPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM50380739(CHEMBL2017837)copy SMILEScopy InChI
Affinity DataKi:  1.63E+4nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli using para-nitrophenyl phosphate as substrate preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53ZSPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM50380745(CHEMBL2017844)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of human recombinant PTP1B expressed in Escherichia coli using para-nitrophenyl phosphate as substrate preincubated for 30 mins followed b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53ZSPubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM13990(5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-(methoxycarbony...)copy SMILEScopy InChI
Affinity DataKi:  1.64E+5nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB53ZSPubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202131(US9233983, I-2)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human full length BTK preincubated for 10 mins followed by Tk-biotin peptide substrate addition after 90 mins by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202199(US9233983, P-14)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human full length BTK preincubated for 10 mins followed by Tk-biotin peptide substrate addition after 90 mins by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202200(US9233983, P-15)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human full length BTK preincubated for 10 mins followed by Tk-biotin peptide substrate addition after 90 mins by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM50450836(CHEMBL4216939)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant human full length BTK preincubated for 10 mins followed by Tk-biotin peptide substrate addition after 90 mins by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202208(US9233983, P-23)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human full length BTK preincubated for 10 mins followed by Tk-biotin peptide substrate addition after 90 mins by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202122(US9233983, D-14)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant human full length BTK preincubated for 10 mins followed by Tk-biotin peptide substrate addition after 90 mins by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202127(US9233983, G-1)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of recombinant human full length BTK preincubated for 10 mins followed by Tk-biotin peptide substrate addition after 90 mins by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202141(US9233983, I-12)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of recombinant human full length BTK preincubated for 10 mins followed by Tk-biotin peptide substrate addition after 90 mins by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202197(US9233983, P-12)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of recombinant human full length BTK preincubated for 10 mins followed by Tk-biotin peptide substrate addition after 90 mins by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202128(US9233983, G-2)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Inhibition of recombinant human full length BTK preincubated for 10 mins followed by Tk-biotin peptide substrate addition after 90 mins by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202130(US9233983, I-1)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Inhibition of recombinant human full length BTK preincubated for 10 mins followed by Tk-biotin peptide substrate addition after 90 mins by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202131(US9233983, I-2)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202196(US9233983, P-11)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inhibition of recombinant human full length BTK preincubated for 10 mins followed by Tk-biotin peptide substrate addition after 90 mins by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202199(US9233983, P-14)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202109(US9233983, D-1)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human full length BTK preincubated for 10 mins followed by Tk-biotin peptide substrate addition after 90 mins by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202082(US9233983, B-1)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMAssay Description:Inhibition of recombinant human full length BTK preincubated for 10 mins followed by Tk-biotin peptide substrate addition after 90 mins by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202087(US9233983, B-6)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:Inhibition of recombinant human full length BTK preincubated for 10 mins followed by Tk-biotin peptide substrate addition after 90 mins by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202122(US9233983, D-14)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202086(US9233983, B-5)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMAssay Description:Inhibition of recombinant human full length BTK preincubated for 10 mins followed by Tk-biotin peptide substrate addition after 90 mins by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202141(US9233983, I-12)copy SMILEScopy InChI
Affinity DataIC50: 8.40nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202105(US9233983, C-2)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human full length BTK preincubated for 10 mins followed by Tk-biotin peptide substrate addition after 90 mins by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202130(US9233983, I-1)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202200(US9233983, P-15)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202196(US9233983, P-11)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202073(US9233983, A-1 | US9233983, B-2)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human full length BTK preincubated for 10 mins followed by Tk-biotin peptide substrate addition after 90 mins by TR-FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202109(US9233983, D-1)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202105(US9233983, C-2)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
TargetTyrosine-protein kinase BTK(Mus musculus)
Advinus Therapeutics Ltd

Curated by ChEMBL
LigandPNGBDBM202197(US9233983, P-12)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of C57BL/6J mouse BTK assessed as decrease in anti-mouse IgM antibody stimulated BCR mediated CD69 upregulation preincubated for 30 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X74PubMed
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