Compile Data Set for Download or QSAR
Found 20 with Last Name = 'pisapia' and Initial = 'v'
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50526221(CHEMBL4454542)copy SMILEScopy InChI
Affinity DataKi:  3.60nMAssay Description:Competitive inhibition of recombinant human G9a using biotinylated-Histone H3 peptide (1 to 21 residues) as substrate after 30 mins in presence of va...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280C10PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50526221(CHEMBL4454542)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Non-competitive inhibition of recombinant human G9a using biotinylated-Histone H3 peptide (1 to 21 residues) as substrate at varying concentration af...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280C10PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50353128(CHEMBL1231795)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition G9a (unknown origin)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50353128(CHEMBL1231795)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of GLP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280C10PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50526221(CHEMBL4454542)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human G9a using biotinylated-Histone H3 peptide (1 to 21 residues) after 30 mins in presence of SAM by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280C10PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50353128(CHEMBL1231795)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human G9a using biotinylated-Histone H3 peptide (1 to 21 residues) after 30 mins in presence of SAM by AlphaLISA assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50396024(CHEMBL1232453)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of GLP (unknown origin)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50396024(CHEMBL1232453)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition G9a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280C10PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50300028(CHEMBL569864 | N-(1-benzylpiperidin-4-yl)-6,7-dime...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of recombinant human GLP (610 to 917 residues) using H3 peptide (1 to 20 residues) by mass spectrometryMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50526220(CHEMBL4539914)copy SMILEScopy InChI
Affinity DataIC50: 955nMAssay Description:Inhibition of recombinant human G9a using biotinylated-Histone H3 peptide (1 to 21 residues) after 30 mins in presence of SAM by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280C10PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50526219(CHEMBL4545884)copy SMILEScopy InChI
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of recombinant human G9a using biotinylated-Histone H3 peptide (1 to 21 residues) after 30 mins in presence of SAM by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280C10PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50075052(CHEMBL3414617)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition G9a (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280C10PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50075052(CHEMBL3414617)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of GLP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280C10PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50300028(CHEMBL569864 | N-(1-benzylpiperidin-4-yl)-6,7-dime...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of recombinant human G9a (685 to 1000 residues) using H3 peptide (1 to 20 residues) by mass spectrometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280C10PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50526218(CHEMBL4569449)copy SMILEScopy InChI
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibition of recombinant human G9a using biotinylated-Histone H3 peptide (1 to 21 residues) after 30 mins in presence of SAM by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280C10PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50526222(CHEMBL4537940)copy SMILEScopy InChI
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of recombinant human G9a using biotinylated-Histone H3 peptide (1 to 21 residues) after 30 mins in presence of SAM by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280C10PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50526221(CHEMBL4454542)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full length human DNMT1 (2 to 1632 residues) using poly(dI-dC)):poly(dI-dC) as substrate preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280C10PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50353128(CHEMBL1231795)copy SMILEScopy InChI
Affinity DataIC50: 1.07E+5nMAssay Description:Inhibition of N-terminal GST-tagged recombinant full length human DNMT1 (2 to 1632 residues) using poly(dI-dC)):poly(dI-dC) as substrate preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280C10PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50526221(CHEMBL4454542)copy SMILEScopy InChI
Affinity DataKd:  1.13E+3nMAssay Description:Binding affinity to human His-tagged G9a expressed in Escherichia coli Rosetta (DE3) after 30 mins by MST binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280C10PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
The University of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50353128(CHEMBL1231795)copy SMILEScopy InChI
Affinity DataKd:  1.42E+3nMAssay Description:Binding affinity to human His-tagged G9a expressed in Escherichia coli Rosetta (DE3) after 30 mins by MST binding assayMore data for this Ligand-Target Pair