Compile Data Set for Download or QSAR
Found 42 with Last Name = 'sarli' and Initial = 'v'
TargetSonic hedgehog protein(Mus musculus (Mouse))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50300863(CHEMBL568011 | N-(3-(1H-Benzo[d]imidazol-2-yl)-4-c...)copy SMILEScopy InChI
Affinity DataIC50: 79.8nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1KPNPubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50249489(CHEMBL514344 | N-(3-(1H-Benzo[d]imidazol-2-yl)-4-c...)copy SMILEScopy InChI
Affinity DataIC50: 97.9nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1KPNPubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50300862(CHEMBL577049 | N-(3-(1H-Benzo[d]imidazol-2-yl)-4-c...)copy SMILEScopy InChI
Affinity DataIC50: 117nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1KPNPubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50300861(CHEMBL567378 | N-(3-(1H-Benzo[d]imidazol-2-yl)-4-c...)copy SMILEScopy InChI
Affinity DataIC50: 119nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1KPNPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))TBA
LigandPNGBDBM50585538(CHEMBL5087579)copy SMILES
Affinity DataIC50: 120nMAssay Description:Inhibition of alphavbeta3 integrin receptor-mediated cell adhesion to vitronectin in human A549 cells preincubated for 30 mins followed by VN substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0DVGPubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50300860(CHEMBL579397 | N-(3-(1H-Benzo[d]imidazol-2-yl)-4-c...)copy SMILEScopy InChI
Affinity DataIC50: 163nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1KPNPubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50300859(CHEMBL568022 | N-(3-(1H-Benzo[d]imidazol-2-yl)-4-c...)copy SMILEScopy InChI
Affinity DataIC50: 185nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1KPNPubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50300858(CHEMBL584688 | N-(3-(1H-Benzo[d]imidazol-2-yl)-4-c...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1KPNPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))TBA
LigandPNGBDBM50585538(CHEMBL5087579)copy SMILES
Affinity DataIC50: 210nMAssay Description:Inhibition of alphavbeta3 integrin receptor-mediated cell adhesion to vitronectin in human WM 266-4 cells preincubated for 30 mins followed by VN sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0DVGPubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50300857(CHEMBL565554 | N-(3-(1H-Benzo[d]imidazol-2-yl)-4-c...)copy SMILEScopy InChI
Affinity DataIC50: 224nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1KPNPubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50300856(CHEMBL583230 | N-(3-(1H-Benzo[d]imidazol-2-yl)-4-c...)copy SMILEScopy InChI
Affinity DataIC50: 251nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1KPNPubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50300855(CHEMBL578143 | N-(3-(1H-Benzo[d]imidazol-2-yl)-4-c...)copy SMILEScopy InChI
Affinity DataIC50: 876nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1KPNPubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Leipzig

LigandPNGBDBM84573(VS-83)copy SMILEScopy InChI
Affinity DataIC50: 1.17E+3nMpH: 6.8 T: 2°CAssay Description:The ATPase activity of the Eg5 motor domain was measured by using the malachite green assay.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HB5PubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50232973(CHEMBL254129 | CYCLOPAMINE)copy SMILEScopy InChI
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1KPNPubMed
TargetSonic hedgehog protein(Mus musculus (Mouse))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50300854(CHEMBL583231 | N-(3-(1H-Benzo[d]imidazol-2-yl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of SHH in mouse Shh-Light2 cells after 48 hrs by Gli1 reporter gene assay in presence of SAGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1KPNPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))TBA
LigandPNGBDBM50390492(CHEMBL2071605)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of alphavbeta3 integrin receptor-mediated cell adhesion to vitronectin in human WM 266-4 cells preincubated for 30 mins followed by VN sub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0DVGPubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Leipzig

LigandPNGBDBM84575(VS-54)copy SMILEScopy InChI
Affinity DataIC50: 1.81E+3nMpH: 6.8 T: 2°CAssay Description:The ATPase activity of the Eg5 motor domain was measured by using the malachite green assay.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HB5PubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Leipzig

LigandPNGBDBM84577(VS-94)copy SMILEScopy InChI
Affinity DataIC50: 2.73E+3nMpH: 6.8 T: 2°CAssay Description:The ATPase activity of the Eg5 motor domain was measured by using the malachite green assay.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HB5PubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Leipzig

LigandPNGBDBM84576(VS-87)copy SMILEScopy InChI
Affinity DataIC50: 2.74E+3nMpH: 6.8 T: 2°CAssay Description:The ATPase activity of the Eg5 motor domain was measured by using the malachite green assay.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HB5PubMed
TargetLow-density lipoprotein receptor-related protein 6(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50135174(CHEMBL3747431)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity to human LRP6 expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction using compound pre-treated DKK1 conditioned ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JRSPubMed
TargetDickkopf-related protein 1(Mus musculus)
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50135174(CHEMBL3747431)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of mouse DKK1 assessed as inhibition of DKK1-alkaline phophatase binding to LRP5 transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TF0067PubMed
TargetLow-density lipoprotein receptor-related protein 6(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50145410(CHEMBL3764819)copy SMILEScopy InChI
Affinity DataIC50: 3.38E+3nMAssay Description:Binding affinity to human LRP6 expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction using compound pre-treated DKK1 conditioned ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JRSPubMed
TargetLow-density lipoprotein receptor-related protein 6(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50145403(CHEMBL3764323)copy SMILEScopy InChI
Affinity DataIC50: 3.74E+3nMAssay Description:Binding affinity to human LRP6 expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction using compound pre-treated DKK1 conditioned ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JRSPubMed
TargetLow-density lipoprotein receptor-related protein 6(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50145379(CHEMBL3765769)copy SMILEScopy InChI
Affinity DataIC50: 3.77E+3nMAssay Description:Binding affinity to human LRP6 expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction using compound pre-treated DKK1 conditioned ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JRSPubMed
TargetLow-density lipoprotein receptor-related protein 6(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50145384(CHEMBL3764205)copy SMILEScopy InChI
Affinity DataIC50: 4.06E+3nMAssay Description:Binding affinity to human LRP6 expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction using compound pre-treated DKK1 conditioned ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JRSPubMed
TargetLow-density lipoprotein receptor-related protein 6(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50145382(CHEMBL3765415)copy SMILEScopy InChI
Affinity DataIC50: 4.33E+3nMAssay Description:Binding affinity to human LRP6 expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction using compound pre-treated DKK1 conditioned ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JRSPubMed
TargetLow-density lipoprotein receptor-related protein 6(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50145409(CHEMBL3765394)copy SMILEScopy InChI
Affinity DataIC50: 4.61E+3nMAssay Description:Binding affinity to human LRP6 expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction using compound pre-treated DKK1 conditioned ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JRSPubMed
TargetLow-density lipoprotein receptor-related protein 6(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50145380(CHEMBL3765591)copy SMILEScopy InChI
Affinity DataIC50: 4.71E+3nMAssay Description:Binding affinity to human LRP6 expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction using compound pre-treated DKK1 conditioned ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JRSPubMed
TargetLow-density lipoprotein receptor-related protein 6(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50145381(CHEMBL3763214)copy SMILEScopy InChI
Affinity DataIC50: 4.87E+3nMAssay Description:Binding affinity to human LRP6 expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction using compound pre-treated DKK1 conditioned ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JRSPubMed
TargetLow-density lipoprotein receptor-related protein 6(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50145377(CHEMBL3764713)copy SMILEScopy InChI
Affinity DataIC50: 5.23E+3nMAssay Description:Binding affinity to human LRP6 expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction using compound pre-treated DKK1 conditioned ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JRSPubMed
TargetLow-density lipoprotein receptor-related protein 6(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50145383(CHEMBL3763953)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Binding affinity to human LRP6 expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction using compound pre-treated DKK1 conditioned ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JRSPubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Leipzig

LigandPNGBDBM84578(VS-17)copy SMILEScopy InChI
Affinity DataIC50: 5.75E+3nMpH: 6.8 T: 2°CAssay Description:The ATPase activity of the Eg5 motor domain was measured by using the malachite green assay.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HB5PubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Leipzig

LigandPNGBDBM84572(VS-42)copy SMILEScopy InChI
Affinity DataIC50: 5.77E+3nMpH: 6.8 T: 2°CAssay Description:The ATPase activity of the Eg5 motor domain was measured by using the malachite green assay.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HB5PubMed
TargetLow-density lipoprotein receptor-related protein 6(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50145378(CHEMBL3764972)copy SMILEScopy InChI
Affinity DataIC50: 6.16E+3nMAssay Description:Binding affinity to human LRP6 expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction using compound pre-treated DKK1 conditioned ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JRSPubMed
TargetLow-density lipoprotein receptor-related protein 6(Homo sapiens (Human))
Aristotle University of Thessaloniki

Curated by ChEMBL
LigandPNGBDBM50135174(CHEMBL3747431)copy SMILEScopy InChI
Affinity DataIC50: 6.38E+3nMAssay Description:Binding affinity to human LRP6 expressed in HEK293 cells assessed as inhibition of DKK1/LRP6 interaction using compound pre-treated DKK1 conditioned ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JRSPubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Leipzig

LigandPNGBDBM84580(VS-91)copy SMILEScopy InChI
Affinity DataIC50: 7.59E+3nMpH: 6.8 T: 2°CAssay Description:The ATPase activity of the Eg5 motor domain was measured by using the malachite green assay.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HB5PubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Leipzig

LigandPNGBDBM84574(VS-12)copy SMILEScopy InChI
Affinity DataIC50: 7.60E+3nMpH: 6.8 T: 2°CAssay Description:The ATPase activity of the Eg5 motor domain was measured by using the malachite green assay.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HB5PubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Leipzig

LigandPNGBDBM84579(VS-77)copy SMILEScopy InChI
Affinity DataIC50: 8.04E+3nMpH: 6.8 T: 2°CAssay Description:The ATPase activity of the Eg5 motor domain was measured by using the malachite green assay.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4HB5PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))TBA
LigandPNGBDBM50585539(CHEMBL5091463)copy SMILES
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of alphavbeta3 integrin receptor-mediated cell adhesion to vitronectin in human WM 266-4 cells preincubated for 30 mins followed by VN sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0DVGPubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University of Leipzig

LigandPNGBDBM50198309((S)-4-(3-Hydroxy-phenyl)-6-methyl-2-thioxo-1,2,3,4...)copy SMILEScopy InChI
Affinity DataIC50: 2.07E+4nMpH: 6.8 T: 2°CAssay Description:The ATPase activity of the Eg5 motor domain was measured by using the malachite green assay.More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))TBA
LigandPNGBDBM50585539(CHEMBL5091463)copy SMILES
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of alphavbeta3 integrin receptor-mediated cell adhesion to vitronectin in human A549 cells preincubated for 30 mins followed by VN substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0DVGPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))TBA
LigandPNGBDBM50390492(CHEMBL2071605)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of alphavbeta3 integrin receptor-mediated cell adhesion to vitronectin in human A549 cells preincubated for 30 mins followed by VN substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0DVGPubMed