Compile Data Set for Download or QSAR
Found 20 with Last Name = 'singh' and Initial = 'vk'
TargetCholecystokinin receptor type A(RAT)
Lucknow University

Curated by ChEMBL
LigandPNGBDBM50208418(2-[5-((E)-2-biphenyl-4-yl-vinyl)-2-hydroxy-benzo[4...)copy SMILEScopy InChI
Affinity DataIC50: 197nMAssay Description:Displacement of [125I](BH)CCK8 from rat CCK1 after 30 mins by receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6K16PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Queen's University at Kingston

US Patent
LigandPNGBDBM112774(US8629135, SW-01)copy SMILEScopy InChI
Affinity DataIC50: 300nMpH: 7.4 T: 2°CAssay Description:Approximately 5-20 μg of purified GST-RET proteins were incubated with 1 mM ATP in 20 μL kinase buffer (10 mM Tris-HCl, 5 mM MgCl2, pH 7.4)...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78CVNUS Patent
TargetCholecystokinin receptor type A(RAT)
Lucknow University

Curated by ChEMBL
LigandPNGBDBM50208419(2-{2-hydroxy-5-[(E)-2-(4-hydroxy-phenyl)-vinyl]-be...)copy SMILEScopy InChI
Affinity DataIC50: 665nMAssay Description:Displacement of [125I](BH)CCK8 from rat CCK1 after 30 mins by receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6K16PubMed
TargetCholecystokinin receptor type A(RAT)
Lucknow University

Curated by ChEMBL
LigandPNGBDBM50208420(2-[2-hydroxy-5-((E)-styryl)-benzo[4,5]imidazo[1,2-...)copy SMILEScopy InChI
Affinity DataIC50: 942nMAssay Description:Displacement of [125I](BH)CCK8 from rat CCK1 after 30 mins by receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6K16PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Queen's University at Kingston

US Patent
LigandPNGBDBM50020712(10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMpH: 7.4 T: 2°CAssay Description:Approximately 5-20 μg of purified GST-RET proteins were incubated with 1 mM ATP in 20 μL kinase buffer (10 mM Tris-HCl, 5 mM MgCl2, pH 7.4)...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78CVNUS Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Queen's University at Kingston

US Patent
LigandPNGBDBM112777(NORTRIPTYLINE | US8629135, SW-02)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMpH: 7.4 T: 2°CAssay Description:Approximately 5-20 μg of purified GST-RET proteins were incubated with 1 mM ATP in 20 μL kinase buffer (10 mM Tris-HCl, 5 mM MgCl2, pH 7.4)...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78CVNUS Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Queen's University at Kingston

US Patent
LigandPNGBDBM112775(US8629135, SW-13)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMpH: 7.4 T: 2°CAssay Description:Approximately 5-20 μg of purified GST-RET proteins were incubated with 1 mM ATP in 20 μL kinase buffer (10 mM Tris-HCl, 5 mM MgCl2, pH 7.4)...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78CVNUS Patent
TargetCholecystokinin receptor type A(Cavia porcellus)
Lucknow University

Curated by ChEMBL
LigandPNGBDBM50208419(2-{2-hydroxy-5-[(E)-2-(4-hydroxy-phenyl)-vinyl]-be...)copy SMILEScopy InChI
Affinity DataIC50: 2.94E+3nMAssay Description:Displacement of [125I](BH)CCK8 from Guinea pig CCK1 after 30 mins by receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6K16PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Queen's University at Kingston

US Patent
LigandPNGBDBM112776(US8629135, SW-12)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMpH: 7.4 T: 2°CAssay Description:Approximately 5-20 μg of purified GST-RET proteins were incubated with 1 mM ATP in 20 μL kinase buffer (10 mM Tris-HCl, 5 mM MgCl2, pH 7.4)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78CVNUS Patent
TargetCholecystokinin receptor type A(Cavia porcellus)
Lucknow University

Curated by ChEMBL
LigandPNGBDBM50208420(2-[2-hydroxy-5-((E)-styryl)-benzo[4,5]imidazo[1,2-...)copy SMILEScopy InChI
Affinity DataIC50: 4.32E+3nMAssay Description:Displacement of [125I](BH)CCK8 from Guinea pig CCK1 after 30 mins by receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6K16PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Queen's University at Kingston

US Patent
LigandPNGBDBM50097219(C-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMpH: 7.4 T: 2°CAssay Description:Approximately 5-20 μg of purified GST-RET proteins were incubated with 1 mM ATP in 20 μL kinase buffer (10 mM Tris-HCl, 5 mM MgCl2, pH 7.4)...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78CVNUS Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Queen's University at Kingston

US Patent
LigandPNGBDBM112777(NORTRIPTYLINE | US8629135, SW-02)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMpH: 7.4 T: 2°CAssay Description:Approximately 5-20 μg of purified GST-RET proteins were incubated with 1 mM ATP in 20 μL kinase buffer (10 mM Tris-HCl, 5 mM MgCl2, pH 7.4)...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78CVNUS Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Queen's University at Kingston

US Patent
LigandPNGBDBM112779(US8629135, SW-11)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:Approximately 5-20 μg of purified GST-RET proteins were incubated with 1 mM ATP in 20 μL kinase buffer (10 mM Tris-HCl, 5 mM MgCl2, pH 7.4)...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78CVNUS Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Queen's University at Kingston

US Patent
LigandPNGBDBM112778(US8629135, SW-03)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:Approximately 5-20 μg of purified GST-RET proteins were incubated with 1 mM ATP in 20 μL kinase buffer (10 mM Tris-HCl, 5 mM MgCl2, pH 7.4)...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78CVNUS Patent
TargetCholecystokinin receptor type A(Cavia porcellus)
Lucknow University

Curated by ChEMBL
LigandPNGBDBM50208418(2-[5-((E)-2-biphenyl-4-yl-vinyl)-2-hydroxy-benzo[4...)copy SMILEScopy InChI
Affinity DataIC50: 1.64E+4nMAssay Description:Displacement of [125I](BH)CCK8 from Guinea pig CCK1 after 30 mins by receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6K16PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Queen's University at Kingston

US Patent
LigandPNGBDBM112782(US8629135, SW-10)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMpH: 7.4 T: 2°CAssay Description:Approximately 5-20 μg of purified GST-RET proteins were incubated with 1 mM ATP in 20 μL kinase buffer (10 mM Tris-HCl, 5 mM MgCl2, pH 7.4)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78CVNUS Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Queen's University at Kingston

US Patent
LigandPNGBDBM112783(US8629135, SW-14)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMpH: 7.4 T: 2°CAssay Description:Approximately 5-20 μg of purified GST-RET proteins were incubated with 1 mM ATP in 20 μL kinase buffer (10 mM Tris-HCl, 5 mM MgCl2, pH 7.4)...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78CVNUS Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Queen's University at Kingston

US Patent
LigandPNGBDBM112780(US8629135, SW-07)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMpH: 7.4 T: 2°CAssay Description:Approximately 5-20 μg of purified GST-RET proteins were incubated with 1 mM ATP in 20 μL kinase buffer (10 mM Tris-HCl, 5 mM MgCl2, pH 7.4)...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78CVNUS Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Queen's University at Kingston

US Patent
LigandPNGBDBM82437(CAS_23047-25-8 | Lofepramine | NSC_3947 | US862913...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMpH: 7.4 T: 2°CAssay Description:Approximately 5-20 μg of purified GST-RET proteins were incubated with 1 mM ATP in 20 μL kinase buffer (10 mM Tris-HCl, 5 mM MgCl2, pH 7.4)...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78CVNUS Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Queen's University at Kingston

US Patent
LigandPNGBDBM112781(US8629135, SW-09)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMpH: 7.4 T: 2°CAssay Description:Approximately 5-20 μg of purified GST-RET proteins were incubated with 1 mM ATP in 20 μL kinase buffer (10 mM Tris-HCl, 5 mM MgCl2, pH 7.4)...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78CVNUS Patent