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Found 585 with Last Name = 'bhosale' and Initial = 'vm'
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

LigandPNGBDBM363753(US9855229, Compound 7)copy SMILEScopy InChI
Affinity DataIC50: 0.615nMAssay Description:The assay is based on the principle that binding of the agonist to the RORγ causes a conformational change around helix 12 in the ligand binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20867MMUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191653(US9186360, 57)copy SMILEScopy InChI
Affinity DataIC50: 1.45nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM60874(US9186360, 62)copy SMILEScopy InChI
Affinity DataIC50: 1.68nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

LigandPNGBDBM363754(US9855229, Compound 8)copy SMILEScopy InChI
Affinity DataIC50: 1.98nMAssay Description:The assay is based on the principle that binding of the agonist to the RORγ causes a conformational change around helix 12 in the ligand binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20867MMUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191709(US9186360, 55)copy SMILEScopy InChI
Affinity DataIC50: 2.15nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

LigandPNGBDBM363752(US9855229, Compound 6)copy SMILEScopy InChI
Affinity DataIC50: 2.18nMAssay Description:The assay is based on the principle that binding of the agonist to the RORγ causes a conformational change around helix 12 in the ligand binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20867MMUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191712(US9186360, 59)copy SMILEScopy InChI
Affinity DataIC50: 2.21nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191652(US9186360, 51 | US9186360, 52)copy SMILEScopy InChI
Affinity DataIC50: 2.49nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191713(US9186360, 61)copy SMILEScopy InChI
Affinity DataIC50: 2.93nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191722(US9186360, 71)copy SMILEScopy InChI
Affinity DataIC50: 3.18nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191656(US9186360, 75)copy SMILEScopy InChI
Affinity DataIC50: 3.34nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191710(US9186360, 56)copy SMILEScopy InChI
Affinity DataIC50: 3.38nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191654(US9186360, 60)copy SMILEScopy InChI
Affinity DataIC50: 3.54nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191655(US9186360, 62 | US9186360, 66)copy SMILEScopy InChI
Affinity DataIC50: 3.63nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191705(US9186360, 49)copy SMILEScopy InChI
Affinity DataIC50: 3.98nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191725(US9186360, 76)copy SMILEScopy InChI
Affinity DataIC50: 4.02nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191723(US9186360, 72)copy SMILEScopy InChI
Affinity DataIC50: 4.16nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

LigandPNGBDBM363747(US9855229, Compound 1)copy SMILEScopy InChI
Affinity DataIC50: 4.26nMAssay Description:The assay is based on the principle that binding of the agonist to the RORγ causes a conformational change around helix 12 in the ligand binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20867MMUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191731(US9186360, 83)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191715(US9186360, 64)copy SMILEScopy InChI
Affinity DataIC50: 4.52nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191719(US9186360, 68)copy SMILEScopy InChI
Affinity DataIC50: 4.84nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191652(US9186360, 51 | US9186360, 52)copy SMILEScopy InChI
Affinity DataIC50: 4.84nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191740(US9186360, 99)copy SMILEScopy InChI
Affinity DataIC50: 5.06nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191741(US9186360, 100)copy SMILEScopy InChI
Affinity DataIC50: 5.15nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191728(US9186360, 79)copy SMILEScopy InChI
Affinity DataIC50: 5.29nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191724(US9186360, 74)copy SMILEScopy InChI
Affinity DataIC50: 5.29nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191666(US9186360, 84)copy SMILEScopy InChI
Affinity DataIC50: 5.35nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191648(US9186360, 33)copy SMILEScopy InChI
Affinity DataIC50: 5.37nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

LigandPNGBDBM363749(US9855229, Compound 3)copy SMILEScopy InChI
Affinity DataIC50: 5.52nMAssay Description:The assay is based on the principle that binding of the agonist to the RORγ causes a conformational change around helix 12 in the ligand binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20867MMUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191726(US9186360, 77)copy SMILEScopy InChI
Affinity DataIC50: 5.60nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM50046740(CHEMBL1939972 | US9186360, 90)copy SMILEScopy InChI
Affinity DataIC50: 5.61nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191647(US9186360, 32)copy SMILEScopy InChI
Affinity DataIC50: 5.96nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

LigandPNGBDBM363750(US9855229, Compound 4)copy SMILEScopy InChI
Affinity DataIC50: 5.99nMAssay Description:The assay is based on the principle that binding of the agonist to the RORγ causes a conformational change around helix 12 in the ligand binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20867MMUS Patent
TargetAlcohol dehydrogenase class-3(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50465807(CHEMBL4291042)copy SMILEScopy InChI
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PZKPubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191657(US9186360, 80)copy SMILEScopy InChI
Affinity DataIC50: 6.28nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191689(US9186360, 28)copy SMILEScopy InChI
Affinity DataIC50: 6.49nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191716(US9186360, 65)copy SMILEScopy InChI
Affinity DataIC50: 6.65nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191729(US9186360, 81)copy SMILEScopy InChI
Affinity DataIC50: 6.74nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191658(US9186360, 86)copy SMILEScopy InChI
Affinity DataIC50: 6.91nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetAlcohol dehydrogenase class-3(Mus musculus)
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50465805(CHEMBL4290485)copy SMILEScopy InChI
Affinity DataIC50: 7.10nMAssay Description:Inhibition of mouse GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PZKPubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191720(US9186360, 69)copy SMILEScopy InChI
Affinity DataIC50: 7.10nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191663(US9186360, 104)copy SMILEScopy InChI
Affinity DataIC50: 7.58nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191742(US9186360, 102)copy SMILEScopy InChI
Affinity DataIC50: 7.67nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191730(US9186360, 82)copy SMILEScopy InChI
Affinity DataIC50: 8.04nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191700(US9186360, 44)copy SMILES
Affinity DataIC50: 8.36nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191665(US9186360, 73)copy SMILEScopy InChI
Affinity DataIC50: 8.54nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Glenmark Pharmaceuticals Ltd.

Curated by ChEMBL
LigandPNGBDBM50442406(CHEMBL2443061)copy SMILEScopy InChI
Affinity DataIC50: 8.90nMAssay Description:Antagonist activity at human TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced 45Ca2+ uptake incubated for 10 mins prior to icili...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8P5SPubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191732(US9186360, 85)copy SMILEScopy InChI
Affinity DataIC50: 8.92nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
GLENMARK PHARMACEUTICALS S.A.

US Patent
LigandPNGBDBM191714(US9186360, 63)copy SMILEScopy InChI
Affinity DataIC50: 9.04nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TX3D5QUS Patent
TargetAlcohol dehydrogenase class-3(Rattus norvegicus)
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50465805(CHEMBL4290485)copy SMILEScopy InChI
Affinity DataIC50: 9.10nMAssay Description:Inhibition of rat GSNOR assessed as reduction in NADH consumption after 3 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PZKPubMed
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