Compile Data Set for Download or QSAR
Found 182 with Last Name = 'paralkar' and Initial = 'vm'
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181274(5-(3-((S)-2-((R)-4-(3-chlorophenyl)-3-hydroxybutyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM35847((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM35847((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W18PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181298(5-(3-((S)-2-((R)-3-hydroxy-4-(3-(trifluoromethyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346031(6-{4-Cyano-3-[(R)-2-hydroxy-3-(2-indan-2-yl-1,1-di...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937V7PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181289(5-(3-((S)-2-(4-(3-fluorophenyl)-3-hydroxybutyl)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346032(6-[2-((R)-1-{(R)-3-[2-(3-Chloro-4-methyl-phenyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937V7PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181296(5-(3-((S)-2-(3-hydroxy-4-phenylbutyl)-5-oxopyrroli...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50142488(7-((S)-2-((R)-3-hydroxy-4-(3-(trifluoromethyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181279(7-(2-(4-(3-chlorophenyl)-3-hydroxybutyl)-5-oxopyrr...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346033(6-(4-Cyano-3-{(R)-3-[2-(3-fluoro-4-methyl-phenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937V7PubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50161093((R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthale...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50318873((1S,2S,3R,4R,5S)-6-{2-[(1R)-1-[(2R)-3-{[1-(3-fluor...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937V7PubMed
TargetProtein-tyrosine kinase 2-beta(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50246060(CHEMBL472212 | CHEMBL541649 | D3RKN_6 | N-methyl-N...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant PYK2More data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181277(4-(3-(2-(4-(3-chlorophenyl)-3-hydroxybutyl)-5-oxop...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181291(4-{3-[2-(4-biphenyl-3-yl-3-hydroxy-butyl)-5-oxo-py...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346034(6-[2-((R)-1-{(R)-3-[2-(4-Chloro-2-fluoro-phenyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937V7PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181290(5-{3-[(S)-2-(4-biphenyl-3-yl-3-hydroxy-butyl)-5-ox...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50293496(2-(3-((N-(4-tert-butylbenzyl)pyridine-3-sulfonamid...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W18PubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50293493(3-(3-((N-(4-tert-butylbenzyl)pyridine-2-sulfonamid...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W18PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181284(7-((S)-2-(3-hydroxy-4-phenylbutyl)-5-oxopyrrolidin...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346035(6-{3,4-Difluoro-5-[(R)-2-hydroxy-3-(2-indan-2-yl-1...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937V7PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181271(7-((S)-2-((R)-3-hydroxy-4-(3-(trifluoromethoxy)phe...)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181293(7-((S)-2-((R)-3-hydroxy-4-(3-(methoxymethyl)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50293495(3-(3-((N-(4-tert-butylbenzyl)thiazole-2-sulfonamid...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W18PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181295(5-(3-((S)-2-(3-hydroxy-4-(naphthalen-2-yl)butyl)-5...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181286(5-(3-((S)-2-((R)-4-(4-fluorophenyl)-3-hydroxybutyl...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181272(4-(3-((S)-2-((R)-3-hydroxy-4-(3-(trifluoromethyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181282(5-(3-((S)-2-(4-(4-chlorophenyl)-3-hydroxybutyl)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181282(5-(3-((S)-2-(4-(4-chlorophenyl)-3-hydroxybutyl)-5-...)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50293498(7-(N-(4-(1-hydroxyhexyl)benzyl)methylsulfonamido)h...)copy SMILEScopy InChI
Affinity DataIC50: 93nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W18PubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181294(5-{3-[(S)-2-(4-biphenyl-2-yl-3-hydroxy-butyl)-5-ox...)copy SMILEScopy InChI
Affinity DataIC50: 125nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181281(4-(3-(2-(4-(3-fluorophenyl)-3-hydroxybutyl)-5-oxop...)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181290(5-{3-[(S)-2-(4-biphenyl-3-yl-3-hydroxy-butyl)-5-ox...)copy SMILEScopy InChI
Affinity DataIC50: 135nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181280(5-(3-((S)-2-(4-(4-ethylphenyl)-3-hydroxybutyl)-5-o...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346036(CHEMBL1198855 | Ronacaleret)copy SMILEScopy InChI
Affinity DataIC50: 146nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937V7PubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50293502(7-(N-(4-butylbenzyl)methylsulfonamido)heptanoic ac...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W18PubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181274(5-(3-((S)-2-((R)-4-(3-chlorophenyl)-3-hydroxybutyl...)copy SMILEScopy InChI
Affinity DataIC50: 188nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181278(7-((S)-2-((R)-3-hydroxy-4-(3-(2-methoxyethyl)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181285(4-(3-(2-(3-hydroxy-4-(3-phenoxyphenyl)butyl)-5-oxo...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50293497(7-(N-(4-hydroxynonyl)methylsulfonamido)heptanoic a...)copy SMILEScopy InChI
Affinity DataIC50: 225nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W18PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181283(4-(3-(2-(3-hydroxy-4-phenylbutyl)-5-oxopyrrolidin-...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50293490(3-(3-((N-(4-butylbenzyl)methylsulfonamido)methyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W18PubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50293492(3-(3-((N-(4-tert-butylbenzyl)phenylsulfonamido)met...)copy SMILEScopy InChI
Affinity DataIC50: 278nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W18PubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50293503(7-(N-(biphenyl-4-ylmethyl)methylsulfonamido)heptan...)copy SMILEScopy InChI
Affinity DataIC50: 289nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W18PubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346037(6-(4-Fluoro-3-{(R)-3-[2-(3-fluoro-4-methyl-phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937V7PubMed
TargetExtracellular calcium-sensing receptor(Rattus norvegicus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346036(CHEMBL1198855 | Ronacaleret)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Negative allosteric modulator activity at rat calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937V7PubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50293494(2-(3-((N-(4-tert-butylbenzyl)-1-(1-methyl-1H-imida...)copy SMILEScopy InChI
Affinity DataIC50: 326nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7W18PubMed
TargetProstaglandin E2 receptor EP4 subtype(Rattus norvegicus)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50181273(7-[(S)-2-((R)-4-biphenyl-3-yl-3-hydroxy-butyl)-5-o...)copy SMILEScopy InChI
Affinity DataIC50: 337nMAssay Description:Binding affinity to rat EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8ZZ5PubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50346038(6-(4-Cyano-3-{(R)-3-[1,1-dimethyl-2-(1-oxo-1,3-dih...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Negative allosteric modulator activity at human recombinant calcium sensing receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K937V7PubMed
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