Compile Data Set for Download or QSAR
Found 72 with Last Name = 'knecht' and Initial = 'w'
TargetProthrombin(Homo sapiens (Human))
Université de Montréal

Curated by ChEMBL
LigandPNGBDBM50331670(CHEMBL1289648)copy SMILEScopy InChI
Affinity DataKi:  0.0900nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q237790BPubMed
TargetProthrombin(Homo sapiens (Human))
Université de Montréal

Curated by ChEMBL
LigandPNGBDBM50331669((6R,21AS)-17-CHLORO-6-CYCLOHEXYL-2,3,6,7,10,11,19,...)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
TargetSerine protease 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50092660(4-Amino-benzamidine | 4-aminobenzamidine | CHEMBL1...)copy SMILEScopy InChI
Affinity DataKi:  8.90E+3nMAssay Description:Inhibition of human recombinant trypsin 1 using tosyl-GPR-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NKCPubMed
TargetTrypsin-3(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50092660(4-Amino-benzamidine | 4-aminobenzamidine | CHEMBL1...)copy SMILEScopy InChI
Affinity DataKi:  1.31E+4nMAssay Description:Inhibition of human recombinant trypsin 4 using tosyl-GPR-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NKCPubMed
TargetProthrombin(Homo sapiens (Human))
Université de Montréal

Curated by ChEMBL
LigandPNGBDBM50092660(4-Amino-benzamidine | 4-aminobenzamidine | CHEMBL1...)copy SMILEScopy InChI
Affinity DataKi:  9.50E+4nMAssay Description:Inhibition of human thrombin using tosyl-GPR-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NKCPubMed
TargetTrypsin-3(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50387180(CHEMBL2047998)copy SMILEScopy InChI
Affinity DataKi:  1.68E+5nMAssay Description:Inhibition of human recombinant trypsin 4 using tosyl-GPR-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NKCPubMed
TargetSerine protease 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50387180(CHEMBL2047998)copy SMILEScopy InChI
Affinity DataKi:  1.98E+5nMAssay Description:Inhibition of human recombinant trypsin 1 using tosyl-GPR-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NKCPubMed
TargetTrypsin-3(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50387183(CHEMBL2048000)copy SMILEScopy InChI
Affinity DataKi:  4.76E+5nMAssay Description:Inhibition of human recombinant trypsin 4 using tosyl-GPR-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NKCPubMed
TargetProthrombin(Homo sapiens (Human))
Université de Montréal

Curated by ChEMBL
LigandPNGBDBM50387180(CHEMBL2047998)copy SMILEScopy InChI
Affinity DataKi:  4.81E+5nMAssay Description:Inhibition of human thrombin using tosyl-GPR-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NKCPubMed
TargetSerine protease 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50387183(CHEMBL2048000)copy SMILEScopy InChI
Affinity DataKi:  6.47E+5nMAssay Description:Inhibition of human recombinant trypsin 1 using tosyl-GPR-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NKCPubMed
TargetTrypsin-3(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50387182(CHEMBL2048003)copy SMILEScopy InChI
Affinity DataKi:  7.94E+5nMAssay Description:Inhibition of human recombinant trypsin 4 using tosyl-GPR-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NKCPubMed
TargetTrypsin-3(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50387181(CHEMBL2047999)copy SMILEScopy InChI
Affinity DataKi:  1.09E+6nMAssay Description:Inhibition of human recombinant trypsin 4 using tosyl-GPR-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NKCPubMed
TargetProthrombin(Homo sapiens (Human))
Université de Montréal

Curated by ChEMBL
LigandPNGBDBM50387181(CHEMBL2047999)copy SMILEScopy InChI
Affinity DataKi:  2.73E+6nMAssay Description:Inhibition of human thrombin using tosyl-GPR-pNA substrate by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3NKCPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365495(CHEMBL1957460)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365480(CHEMBL1957366)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365481(CHEMBL1957367)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365484(CHEMBL1955881)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365487(CHEMBL1957375)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365483(CHEMBL1957369)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50209531((R)-2-[3-cyano-2-(2'-ethoxy-biphenyl-4-yl)-6-fluor...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365486(CHEMBL1957374)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365476(CHEMBL1957361)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365500(CHEMBL1957462)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365479(CHEMBL1957364)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365485(CHEMBL1957373)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365482(CHEMBL1957368)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365494(CHEMBL1957381)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365496(CHEMBL1957370)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM31589(triaryl imidazole, 1)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM14754(1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-isoq...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365492(CHEMBL1957379)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365478(CHEMBL1957363)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365490(CHEMBL1957377)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365493(CHEMBL1957380)copy SMILEScopy InChI
Affinity DataIC50: 97nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365488(CHEMBL1957365)copy SMILEScopy InChI
Affinity DataIC50: 108nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365489(CHEMBL1957376)copy SMILEScopy InChI
Affinity DataIC50: 144nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365480(CHEMBL1957366)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant DHODH transmembrane domain using 2,6-dichloroindophenol sodium, L-Dihydroorotic acid, and decylubiquinone as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365477(CHEMBL1957362)copy SMILEScopy InChI
Affinity DataIC50: 315nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365491(CHEMBL1957378)copy SMILEScopy InChI
Affinity DataIC50: 456nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365475(CHEMBL1957360)copy SMILEScopy InChI
Affinity DataIC50: 561nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365499(CHEMBL1957461)copy SMILEScopy InChI
Affinity DataIC50: 608nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365497(CHEMBL1957372)copy SMILEScopy InChI
Affinity DataIC50: 746nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365500(CHEMBL1957462)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant DHODH transmembrane domain using 2,6-dichloroindophenol sodium, L-Dihydroorotic acid, and decylubiquinone as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365495(CHEMBL1957460)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant DHODH transmembrane domain using 2,6-dichloroindophenol sodium, L-Dihydroorotic acid, and decylubiquinone as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetProthrombin(Homo sapiens (Human))
Université de Montréal

Curated by ChEMBL
LigandPNGBDBM50118723(CHEMBL342672 | CYCLOTHEONAMIDE A | N-[14-Benzyl-18...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q237790BPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365474(CHEMBL1957359)copy SMILEScopy InChI
Affinity DataIC50: 1.72E+3nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365498(CHEMBL1957371)copy SMILEScopy InChI
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of human recombinant full length PDE10A using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365480(CHEMBL1957366)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human recombinant full length PDE2A3 using cAMP as substrate preincubated for 20 mins measured after 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
TargetProthrombin(Homo sapiens (Human))
Université de Montréal

Curated by ChEMBL
LigandPNGBDBM50301574(CHEMBL568990 | Chlorodysinosin A)copy SMILEScopy InChI
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q237790BPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50365493(CHEMBL1957380)copy SMILEScopy InChI
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human recombinant DHODH transmembrane domain using 2,6-dichloroindophenol sodium, L-Dihydroorotic acid, and decylubiquinone as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NTPPubMed
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