Compile Data Set for Download or QSAR
Found 135 with Last Name = 'lea' and Initial = 'wa'
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50068039(1-{3-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Binding affinity to human SST4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77XJPubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50496732(CHEMBL1591268)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Binding affinity to human SST4 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77XJPubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50496735(CHEMBL1355048)copy SMILEScopy InChI
Affinity DataKi:  26nMAssay Description:Binding affinity to human SST4 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77XJPubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50496733(CHEMBL1591395)copy SMILEScopy InChI
Affinity DataKi:  160nMAssay Description:Binding affinity to human SST4 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77XJPubMed
TargetSomatostatin receptor type 4(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50496734(CHEMBL1590268)copy SMILEScopy InChI
Affinity DataKi:  690nMAssay Description:Binding affinity to human SST4 receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP77XJPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
National Center for Advancing Translation Sciences

Curated by ChEMBL
LigandPNGBDBM18428(Aminoquinoline compound, 1 | N-[4-methyl-2-(morpho...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of wild type glucocerebrosidase using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70GZ1PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
National Center for Advancing Translation Sciences

Curated by ChEMBL
LigandPNGBDBM50182801((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of wild type glucocerebrosidase using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to substrate addition measured aft...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM228659((+)-2-(2-(1H-Benzo[d]imidazol-1-yl)-N-(3-fluorophe...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:The activity of IDH1 R132H and IDH1 R132C was measured in 384-well plates by coupling NADPH consumption to a diaphorase/resazurin-based detection sys...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513X35PubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM35361((5-oxidanidyl-4-thiophen-2-ylcarbonyl-1,2,5-oxadia...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MS1PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132C](Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM228658(rac-ML309)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:The activity of IDH1 R132H and IDH1 R132C was measured in 384-well plates by coupling NADPH consumption to a diaphorase/resazurin-based detection sys...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513X35PubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300734(4-thienoyl-3-cyanofuroxan | CHEMBL576265)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MS1PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM228659((+)-2-(2-(1H-Benzo[d]imidazol-1-yl)-N-(3-fluorophe...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:The activity of IDH1 R132H and IDH1 R132C was measured in 384-well plates by coupling NADPH consumption to a diaphorase/resazurin-based detection sys...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513X35PubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
National Institutes of Health

LigandPNGBDBM228658(rac-ML309)copy SMILEScopy InChI
Affinity DataIC50: 96nMAssay Description:The activity of IDH1 R132H and IDH1 R132C was measured in 384-well plates by coupling NADPH consumption to a diaphorase/resazurin-based detection sys...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513X35PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
National Center for Advancing Translation Sciences

Curated by ChEMBL
LigandPNGBDBM18438(4-benzenesulfonamido-N-(5-ethyl-1,3,4-thiadiazol-2...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of wild type glucocerebrosidase using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70GZ1PubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300756(3-formyl-4-phenyl-1,2,5-oxadiazole 2-oxide | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MS1PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
National Center for Advancing Translation Sciences

Curated by ChEMBL
LigandPNGBDBM50396168(CHEMBL1361379)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of wild type glucocerebrosidase in human spleen homogenate using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to subs...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70GZ1PubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300760(4,4'-(thiophene-2,4-diyl)bis(3-cyano-1,2,5-oxadiaz...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MS1PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
National Center for Advancing Translation Sciences

Curated by ChEMBL
LigandPNGBDBM50068039(1-{3-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of wild type glucocerebrosidase in human spleen homogenate using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to subs...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70GZ1PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
National Center for Advancing Translation Sciences

Curated by ChEMBL
LigandPNGBDBM18447(2-({4-[(5-chloro-2-methoxyphenyl)amino]-6-(pyrroli...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of wild type glucocerebrosidase using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70GZ1PubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300761(4,4'-(thiophene-2,5-diyl)bis(3-cyano-1,2,5-oxadiaz...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MS1PubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300762(4,4'-(5-fluoro-1,3-phenylene)bis(3-cyano-1,2,5-oxa...)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MS1PubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300755(3-carboxy-4-phenyl-1,2,5-oxadiazole 2-oxide | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 630nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MS1PubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
National Center for Advancing Translation Sciences

Curated by ChEMBL
LigandPNGBDBM50068039(1-{3-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)...)copy SMILEScopy InChI
Affinity DataIC50: 710nMAssay Description:Inhibition of wild type glucocerebrosidase using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to substrate addition measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70GZ1PubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398032(CHEMBL1603014)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398032(CHEMBL1603014)copy SMILEScopy InChI
Affinity DataIC50: 940nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300763(4,4'-(1,4-phenylene)bis(3-cyano-1,2,5-oxadiazole 2...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MS1PubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398022(CHEMBL2181097)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398022(CHEMBL2181097)copy SMILEScopy InChI
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398020(CHEMBL2181103)copy SMILEScopy InChI
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398020(CHEMBL2181103)copy SMILEScopy InChI
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398029(CHEMBL2180814)copy SMILEScopy InChI
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
National Center for Advancing Translation Sciences

Curated by ChEMBL
LigandPNGBDBM18428(Aminoquinoline compound, 1 | N-[4-methyl-2-(morpho...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of wild type glucocerebrosidase in human spleen homogenate using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to subs...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70GZ1PubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300753(3-cyano-4-(3-nitrophenyl)-1,2,5-oxadiazole 2-oxide...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MS1PubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398029(CHEMBL2180814)copy SMILEScopy InChI
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300752(3-cyano-4-(3-(trifluoromethyl)phenyl)-1,2,5-oxadia...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MS1PubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300750(4-(3-bromophenyl)-3-cyano-1,2,5-oxadiazole 2-oxide...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MS1PubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300736(3-cyano-4-(furan-2-yl)-1,2,5-oxadiazole 2-oxide | ...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MS1PubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300751(4-(3-bromo-4-fluorophenyl)-3-cyano-1,2,5-oxadiazol...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MS1PubMed
TargetEyes absent homolog 2 [253-538](Homo sapiens (Human))
University of Colorado School of Medicine

LigandPNGBDBM231626(NCGC00249327)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMpH: 6.5 T: 2°CAssay Description:Eya activity was measured in 50-μl reactions using black, 96-well, half-volume microtiter plates (Greiner Bio-one) with the substrate OMFP (3-O-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC0ZJKPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398028(CHEMBL2180816)copy SMILEScopy InChI
Affinity DataIC50: 2.91E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
National Center for Advancing Translation Sciences

Curated by ChEMBL
LigandPNGBDBM18438(4-benzenesulfonamido-N-(5-ethyl-1,3,4-thiadiazol-2...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of wild type glucocerebrosidase in human spleen homogenate using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to subs...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70GZ1PubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398027(CHEMBL2181089)copy SMILEScopy InChI
Affinity DataIC50: 3.26E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398028(CHEMBL2180816)copy SMILEScopy InChI
Affinity DataIC50: 3.26E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300735(3-cyano-4-(thiophen-2-yl)-1,2,5-oxadiazole 2-oxide...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MS1PubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300748(4-(4-bromophenyl)-3-cyano-1,2,5-oxadiazole 2-oxide...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MS1PubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300749(4-(3-chlorophenyl)-3-cyano-1,2,5-oxadiazole 2-oxid...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MS1PubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300759(4,4'-(1,3-phenylene)bis(3-cyano-1,2,5-oxadiazole 2...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MS1PubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398027(CHEMBL2181089)copy SMILEScopy InChI
Affinity DataIC50: 3.66E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
National Center for Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50398024(CHEMBL2181095)copy SMILEScopy InChI
Affinity DataIC50: 3.66E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetThioredoxin glutathione reductase(Schistosoma mansoni)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50300747(4-(4-chlorophenyl)-3-cyano-1,2,5-oxadiazole 2-oxid...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Schistosoma mansoni TGRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MS1PubMed
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