Compile Data Set for Download or QSAR
Found 142 with Last Name = 'schmalhofer' and Initial = 'wa'
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166790(CHEMBL364912 | {2-[2-(4-Chloro-phenyl)-thiazol-4-y...)copy SMILEScopy InChI
Affinity DataKi:  140nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel electrophysiology in inactivated state expressed in HEK293 cells using Voltage/Ion Probe Re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166787(CHEMBL195235 | {2-[2-(4-Chloro-phenyl)-thiazol-4-y...)copy SMILEScopy InChI
Affinity DataKi:  160nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel electrophysiology in inactivated state expressed in HEK293 cells using Voltage/Ion Probe Re...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125504(CHEMBL16806 | Methyl-carbamic acid 4-[(2-methoxy-b...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of DiTc binding to Kv1.3 channel in human brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125521(CHEMBL16804 | Propyl-carbamic acid 4-[(2-methoxy-b...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of DiTc binding to Kv1.3 channel in human brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125498(Allyl-carbamic acid 4-[(2-methoxy-benzoylamino)-me...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125501(CHEMBL16255 | N-[4-(3-Allyl-ureido)-1-phenyl-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of DiTc binding to Kv1.3 channel in human brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166785(1-{2-[2-(4-Chloro-phenyl)-thiazol-4-ylmethoxy]-ben...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:In vitro inhibitory concentration against displacement of 35[S] MK-499 binding to hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166788(1-{2-[2-(4-Chloro-phenyl)-thiazol-4-ylmethoxy]-3-m...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:In vitro inhibitory concentration against displacement of 35[S] MK-499 binding to hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125509(Allyl-carbamic acid 4-[(5-fluoro-2-methoxy-benzoyl...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125521(CHEMBL16804 | Propyl-carbamic acid 4-[(2-methoxy-b...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channelMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125504(CHEMBL16806 | Methyl-carbamic acid 4-[(2-methoxy-b...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channelMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125498(Allyl-carbamic acid 4-[(2-methoxy-benzoylamino)-me...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channelMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125513(CHEMBL277598 | {4-[(2-Methoxy-benzoylamino)-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of T-cell proliferation was determined by a human T-cell assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125512(CHEMBL16468 | N-(4-Benzoylamino-1-phenyl-cyclohexy...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125531(CHEMBL16848 | Isopropyl-carbamic acid 4-[(2-methox...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125516(CHEMBL279606 | Propyl-carbamic acid 4-[(2-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of T-cell proliferation was determined by a human T-cell assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125526(CHEMBL16683 | N-[4-(3-Allyl-ureido)-1-phenyl-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of DiTc binding to Kv1.3 channel in human brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125502((2-Methyl-allyl)-carbamic acid 4-[(2-methoxy-benzo...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of T-cell proliferation was determined by a human T-cell assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125524(Butyl-carbamic acid 4-[(2-methoxy-benzoylamino)-me...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of T-cell proliferation was determined by a human T-cell assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125513(CHEMBL277598 | {4-[(2-Methoxy-benzoylamino)-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of [125I]-(D-Pro10)-Dynorphin A binding to human kappa opioid receptor from membranes of HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125510((2-Hydroxy-ethyl)-carbamic acid 4-[(2-methoxy-benz...)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125522(CHEMBL16945 | Methyl-carbamic acid 4-[(2-methoxy-b...)copy SMILEScopy InChI
Affinity DataIC50: 99nMAssay Description:Inhibition of T-cell proliferation was determined by a human T-cell assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125507(CHEMBL277064 | N-[4-((E)-But-2-enoylamino)-1-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of T-cell proliferation was determined by a human T-cell assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125516(CHEMBL279606 | Propyl-carbamic acid 4-[(2-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channelMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125517(CHEMBL16983 | Phenyl-carbamic acid 4-[(2-methoxy-b...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of T-cell proliferation was determined by a human T-cell assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125529(CHEMBL277812 | Carbamic acid 4-[(2-methoxy-benzoyl...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125515(2-Methoxy-N-[1-phenyl-4-(3-phenyl-propionylamino)-...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of T-cell proliferation was determined by a human T-cell assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125559((2-Methyl-allyl)-carbamic acid 4-[(2-methoxy-benzo...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125496((3-Methoxy-propyl)-carbamic acid 4-[(2-methoxy-ben...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125511(2-Methoxy-N-(1-phenyl-4-phenylacetylamino-cyclohex...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125506(CHEMBL16766 | Isopropyl-carbamic acid 4-[(2-methox...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125494(Allyl-carbamic acid 4-[(2-methoxy-benzoylamino)-me...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channelMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125497(CHEMBL417995 | {4-[(2-Methoxy-benzoylamino)-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 135nMAssay Description:Inhibition of [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channelMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125562((2-Methoxy-ethyl)-carbamic acid 4-[(2-methoxy-benz...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125494(Allyl-carbamic acid 4-[(2-methoxy-benzoylamino)-me...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of DiTc binding to Kv1.3 channel in human brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125514(Allyl-carbamic acid 4-[(5-fluoro-2-hydroxy-benzoyl...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125526(CHEMBL16683 | N-[4-(3-Allyl-ureido)-1-phenyl-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channelMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125557((2-Methoxy-ethyl)-carbamic acid 4-[(2-methoxy-benz...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125556(Butyl-carbamic acid 4-[(2-methoxy-benzoylamino)-me...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125505((3-Methoxy-propyl)-carbamic acid 4-[(2-methoxy-ben...)copy SMILEScopy InChI
Affinity DataIC50: 145nMAssay Description:Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125537(Allyl-methyl-carbamic acid 4-[(2-methoxy-benzoylam...)copy SMILEScopy InChI
Affinity DataIC50: 145nMAssay Description:Inhibition of DiTc binding to Kv1.3 channel in human brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125555(2-Methoxy-N-(3-methyl-2-phenyl-butyl)-benzamide | ...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125522(CHEMBL16945 | Methyl-carbamic acid 4-[(2-methoxy-b...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channelMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125538(CHEMBL16877 | {4-[(2-Methoxy-benzoylamino)-methyl]...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channelMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125501(CHEMBL16255 | N-[4-(3-Allyl-ureido)-1-phenyl-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of T-cell proliferation was determined by a human T-cell assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125512(CHEMBL16468 | N-(4-Benzoylamino-1-phenyl-cyclohexy...)copy SMILEScopy InChI
Affinity DataIC50: 154nMAssay Description:Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166802(1-[3-Methoxy-2-(2-phenyl-thiazol-4-ylmethoxy)-benz...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:In vitro inhibitory concentration against displacement of 35[S] MK-499 binding to hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X929TBPubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125504(CHEMBL16806 | Methyl-carbamic acid 4-[(2-methoxy-b...)copy SMILEScopy InChI
Affinity DataIC50: 195nMAssay Description:Inhibition of DiTc binding to Kv1.3 channel in human brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125539(CHEMBL16917 | N-[4-(3-Allyl-3-methyl-ureido)-1-phe...)copy SMILEScopy InChI
Affinity DataIC50: 195nMAssay Description:Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50125546(2-Methoxy-N-(4-oxo-1-phenyl-cyclohexylmethyl)-benz...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of Kv1.3 ion channel. Measured in the Rb_Kv assay: [86Rb+] efflux from CHO cells stably transfected with Kv1.3 channel.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W09596PubMed
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