Compile Data Set for Download or QSAR
Found 159 with Last Name = 'cornell' and Initial = 'wd'
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30369(piperidinyl glycine derivative, 24f)copy SMILEScopy InChI
Affinity DataKi:  0.190nM ΔG°:  -54.9kJ/mole IC50: 0.5nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM11863(4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...)copy SMILEScopy InChI
Affinity DataKi:  0.280nM ΔG°:  -54.0kJ/mole IC50: 0.300nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30344(Cipemastat | Trocade)copy SMILEScopy InChI
Affinity DataKi:  0.530nM ΔG°:  -52.4kJ/mole IC50: 3.5nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)copy SMILEScopy InChI
Affinity DataKi:  1.27nM ΔG°:  -50.3kJ/mole IC50: 1.90nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30345(BOC-piperidinyl glycine derivative, 9)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30356(BOC-piperidinyl glycine derivative, 31)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30380(piperidinyl glycine derivative, 24q)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30384(piperidinyl glycine derivative, 24u)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30360(BOC-piperidinyl glycine derivative, 35)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30383(piperidinyl glycine derivative, 24t)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30359(BOC-piperidinyl glycine derivative, 34)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30379(piperidinyl glycine derivative, 24p)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30382(piperidinyl glycine derivative, 24s)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30367(piperidinyl glycine derivative, 24d)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30397(piperidinyl glycine derivative, 27d)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30396(piperidinyl glycine derivative, 27c)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30357(BOC-piperidinyl glycine derivative, 32)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30347(BOC-piperidinyl glycine derivative, 22a)copy SMILEScopy InChI
Affinity DataIC50: 0.75nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30370(piperidinyl glycine derivative, 24g)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30387(piperidinyl glycine derivative, 25c)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30378(piperidinyl glycine derivative, 24o)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30372(piperidinyl glycine derivative, 24i)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30381(piperidinyl glycine derivative, 24r)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30392(piperidinyl glycine derivative, 26d)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30377(piperidinyl glycine derivative, 24n)copy SMILEScopy InChI
Affinity DataIC50: 1nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30395(piperidinyl glycine derivative, 27b)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30364(piperidinyl glycine derivative, 24a)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30373(piperidinyl glycine derivative, 24j)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30394(piperidinyl glycine derivative, 27a)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30385(piperidinyl glycine derivative, 25a)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30386(piperidinyl glycine derivative, 25b)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30393(piperidinyl glycine derivative, 26e)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Novartis

LigandPNGBDBM11863(4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...)copy SMILEScopy InChI
Affinity DataIC50: 2nMT: 2°CAssay Description:Test compounds were serially diluted in deep well plates, and an aliquot of the inhibitor solutions was transferred to a Biomek deep well plate conta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30376(piperidinyl glycine derivative, 24m)copy SMILEScopy InChI
Affinity DataIC50: 2nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30368(piperidinyl glycine derivative, 24e)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Novartis

LigandPNGBDBM30344(Cipemastat | Trocade)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMT: 2°CAssay Description:Test compounds were serially diluted in deep well plates, and an aliquot of the inhibitor solutions was transferred to a Biomek deep well plate conta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30358(BOC-piperidinyl glycine derivative, 33)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Novartis

LigandPNGBDBM30344(Cipemastat | Trocade)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMT: 2°CAssay Description:Test compounds were serially diluted in deep well plates, and an aliquot of the inhibitor solutions was transferred to a Biomek deep well plate conta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30388(piperidinyl glycine derivative, 25d)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30366(piperidinyl glycine derivative, 24c)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30375(piperidinyl glycine derivative, 24l)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30391(piperidinyl glycine derivative, 26c)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30374(piperidinyl glycine derivative, 24k)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30371(piperidinyl glycine derivative, 24h)copy SMILEScopy InChI
Affinity DataIC50: 4nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetHistone deacetylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50422364(TRAPOXIN B)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Concentration required to inhibit the partially purified HDAC enzyme by 50% obtained from H1299 cell lysateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T156D5PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30399(piperidinyl glycine derivative, 27f)copy SMILEScopy InChI
Affinity DataIC50: 4nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30400(piperidinyl glycine derivative, 27g)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetHistone deacetylase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50422364(TRAPOXIN B)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Concentration required to inhibit human Histone deacetylase (HDAC) enzyme by 50%More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T156D5PubMed
TargetCollagenase 3(Homo sapiens (Human))
Novartis

LigandPNGBDBM30398(piperidinyl glycine derivative, 27e)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Novartis

LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMT: 2°CAssay Description:Test compounds were serially diluted in deep well plates, and an aliquot of the inhibitor solutions was transferred to a Biomek deep well plate conta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27SN3PubMed
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