Found 77 with Last Name = 'fantegrossi' and Initial = 'we' TargetCannabinoid receptor 1(Mus musculus (Mouse))
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
Affinity DataKi: 0.370nM ΔG°: -53.8kJ/moleT: 2°CAssay Description:Competition receptor binding was performed as previously described [Shoemaker et al., J. Pharmacol. Exp. Ther., 314:868-75]. Briefly, 50 μg of mou...More data for this Ligand-Target Pair
Affinity DataKi: 0.810nMAssay Description:Agonist activity at human CB2 receptor transfected in CHO cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 min...More data for this Ligand-Target Pair
Affinity DataKi: 0.810nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Mus musculus (Mouse))
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
Affinity DataKi: 1.70nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Mus musculus (Mouse))
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
Affinity DataKi: 1.70nMAssay Description:Agonist activity at CB1 receptor in mouse Neuro2a cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 mins by liq...More data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Displacement of [3H]Prazosin from human adrenergic alpha1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 9.80nMAssay Description:Agonist activity at human CB2 receptor transfected in CHO cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 min...More data for this Ligand-Target Pair
Affinity DataKi: 9.80nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
Affinity DataKi: 10.9nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Agonist activity at human CB2 receptor transfected in CHO cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 min...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Mus musculus (Mouse))
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
Affinity DataKi: 12.9nM ΔG°: -45.0kJ/moleT: 2°CAssay Description:Competition receptor binding was performed as previously described [Shoemaker et al., J. Pharmacol. Exp. Ther., 314:868-75]. Briefly, 50 μg of mou...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Mus musculus (Mouse))
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
Affinity DataKi: 12.9nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Mus musculus (Mouse))
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
Affinity DataKi: 13nMAssay Description:Agonist activity at CB1 receptor in mouse Neuro2a cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 mins by liq...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Mus musculus (Mouse))
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
Affinity DataKi: 14.1nM ΔG°: -44.8kJ/moleT: 2°CAssay Description:Competition receptor binding was performed as previously described [Shoemaker et al., J. Pharmacol. Exp. Ther., 314:868-75]. Briefly, 50 μg of mou...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Mus musculus (Mouse))
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
Affinity DataKi: 15nMAssay Description:Agonist activity at CB1 receptor in mouse Neuro2a cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 mins by liq...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Mus musculus (Mouse))
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
Affinity DataKi: 15.4nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Mus musculus (Mouse))
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
Affinity DataKi: 24nMAssay Description:Agonist activity at CB1 receptor in mouse Neuro2a cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 mins by liq...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Mus musculus (Mouse))
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
Affinity DataKi: 24.2nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
Affinity DataKi: 26.5nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Agonist activity at human CB2 receptor transfected in CHO cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 min...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Mus musculus (Mouse))
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
Affinity DataKi: 37nMAssay Description:Agonist activity at CB1 receptor in mouse Neuro2a cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 mins by liq...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Mus musculus (Mouse))
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
Affinity DataKi: 37.3nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Affinity DataKi: 49nMAssay Description:Displacement of [3H]GR127543 from human 5HT1D receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Affinity DataKi: 67nMAssay Description:Displacement of [3H]LSD from human 5HT7 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 78nMAssay Description:Agonist activity at human CB2 receptor transfected in CHO cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 min...More data for this Ligand-Target Pair
Affinity DataKi: 78.3nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Displacement of [3H]GR127543 from human 5HT1B receptorMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Mus musculus (Mouse))
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
Affinity DataKi: 122nM ΔG°: -39.5kJ/moleT: 2°CAssay Description:Competition receptor binding was performed as previously described [Shoemaker et al., J. Pharmacol. Exp. Ther., 314:868-75]. Briefly, 50 μg of mou...More data for this Ligand-Target Pair
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Affinity DataKi: 181nMAssay Description:Displacement of [3H]Clonidine from human adrenergic Alpha-2C receptorMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Mus musculus (Mouse))
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
Affinity DataKi: 224nM ΔG°: -38.0kJ/moleT: 2°CAssay Description:Competition receptor binding was performed as previously described [Shoemaker et al., J. Pharmacol. Exp. Ther., 314:868-75]. Briefly, 50 μg of mou...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Affinity DataKi: 244nMAssay Description:Displacement of [3H]Citalopram from human SERTMore data for this Ligand-Target Pair
Affinity DataKi: 251nM ΔG°: -37.7kJ/moleT: 2°CAssay Description:Competition receptor binding was performed as previously described [Shoemaker et al., J. Pharmacol. Exp. Ther., 314:868-75]. Briefly, 50 μg of mou...More data for this Ligand-Target Pair
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Affinity DataKi: 252nMAssay Description:Displacement of [3H]Clonidine from human adrenergic alpha2B receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Affinity DataKi: 257nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptorMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Affinity DataKi: 262nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 281nMAssay Description:Agonist activity at human CB2 receptor transfected in CHO cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 min...More data for this Ligand-Target Pair
Affinity DataKi: 281nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Affinity DataKi: 309nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptorMore data for this Ligand-Target Pair
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Affinity DataKi: 340nMAssay Description:Binding affinity to human adrenergic Alpha-1D receptorMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Mus musculus (Mouse))
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
Affinity DataKi: 387nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Mus musculus (Mouse))
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
Affinity DataKi: 387nMAssay Description:Agonist activity at CB1 receptor in mouse Neuro2a cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 mins by liq...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Affinity DataKi: 543nMAssay Description:Displacement of [3H]LSD from human 5HT2B receptorMore data for this Ligand-Target Pair
TargetHistamine H2 receptor(Homo sapiens (Human))
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Affinity DataKi: 672nMAssay Description:Displacement of [3H]Tiotidine from human histamine H2 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Affinity DataKi: 832nMAssay Description:Displacement of [3H]Ketanserin from human 5HT2A receptorMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Affinity DataKi: 858nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptorMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Affinity DataKi: 895nMAssay Description:Displacement of [3H]SCH233930 from human dopamine D1 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Affinity DataKi: 1.07E+3nMAssay Description:Displacement of [3H]Mesulergine from human 5HT2C receptorMore data for this Ligand-Target Pair
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Affinity DataKi: 1.19E+3nMAssay Description:Displacement of [3H]Prazosin from human adrenergic Alpha-1B receptorMore data for this Ligand-Target Pair
TargetCannabinoid receptor 1(Mus musculus (Mouse))
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
The Board of Trustees of the University of Arkansas; The University of Kansas
US Patent
Affinity DataKi: 1.28E+3nM ΔG°: -33.6kJ/moleT: 2°CAssay Description:Competition receptor binding was performed as previously described [Shoemaker et al., J. Pharmacol. Exp. Ther., 314:868-75]. Briefly, 50 μg of mou...More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Hunter College and the Graduate Center of the City University of New York
Curated by ChEMBL
Affinity DataKi: 1.29E+3nMAssay Description:Displacement of [3H]Clonidine from human adrenergic alpha2A receptorMore data for this Ligand-Target Pair
