Compile Data Set for Download or QSAR
Found 15 with Last Name = 'hume' and Initial = 'we'
TargetMultidrug and toxin extrusion protein 1(Mus musculus)
RIKEN Center for Life Science Technologies

Curated by ChEMBL
LigandPNGBDBM18512(5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |...)copy SMILEScopy InChI
Affinity DataKi:  145nMAssay Description:Inhibition of mouse Mate1 transfected in HEK293 cells assessed as uptake of [14C]-TEA preincubated for 15 mins by liquid scintillation counting analy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN75C7PubMed
TargetSolute carrier family 22 member 1(Mus musculus)
RIKEN Center for Life Science Technologies

Curated by ChEMBL
LigandPNGBDBM18512(5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |...)copy SMILEScopy InChI
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of mouse Oct1 transfected in HEK293 cells assessed as uptake of [14C]-TEA preincubated for 15 mins by liquid scintillation counting analys...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN75C7PubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50292221((S)-3-(2,4-Dichloro-phenyl)-1-(2-diethylamino-ethy...)copy SMILEScopy InChI
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FWDPubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50366689(GHRELIN)copy SMILEScopy InChI
Affinity DataIC50: 0.140nMAssay Description:Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FWDPubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50292225((S)-3-(2,5-Dichloro-phenyl)-1-(2-diethylamino-ethy...)copy SMILEScopy InChI
Affinity DataIC50: 0.240nMAssay Description:Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FWDPubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50292228((S)-3-(2,3-Dichloro-phenyl)-1-(2-diethylamino-ethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FWDPubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50151162((S)-3-(2-Chloro-phenyl)-1-(2-diethylamino-ethyl)-3...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FWDPubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50151162((S)-3-(2-Chloro-phenyl)-1-(2-diethylamino-ethyl)-3...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FWDPubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50292230((S)-3-(2,6-Dichloro-phenyl)-1-(2-diethylamino-ethy...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FWDPubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50292223((R)-3-(3-Chloro-phenyl)-1-(2-diethylamino-ethyl)-3...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FWDPubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50292227((R)-1-(2-Diethylamino-ethyl)-3-hydroxy-3-(3-methox...)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FWDPubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50292226((R)-3-(4-Chloro-phenyl)-1-(2-diethylamino-ethyl)-3...)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FWDPubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50292229((R)-1-(2-Diethylamino-ethyl)-3-hydroxy-3-(4-methox...)copy SMILEScopy InChI
Affinity DataIC50: 106nMAssay Description:Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FWDPubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50292224(1-(2-Diethylamino-ethyl)-3-hydroxy-2-oxo-3-phenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 116nMAssay Description:Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FWDPubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Sumitomo Pharmaceuticals Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50292222((S)-1-(2-Diethylamino-ethyl)-3-hydroxy-3-(2-methox...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of [125I]ghrelin binding to human recombinant ghrelin receptor membrane preparationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0FWDPubMed