Compile Data Set for Download or QSAR
Found 289 with Last Name = 'leister' and Initial = 'wh'
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248651(2,4-dichloro-N-((4-(6-methylpyridin-2-yl)-1-(propy...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248641(2-amino-6-chloro-N-((4-phenyl-1-(propylsulfonyl)pi...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of glycine transporter 1 (unknown origin) by HTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248064(2,4-dichloro-N-((4-(2-hydroxycyclohexyl)-1-(propyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248062(2,4-dichloro-N-((1-(propylsulfonyl)-4-((tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248669(2-chloro-N-((4-(6-methylpyridin-2-yl)-1-(propylsul...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248058((S)-2,4-dichloro-N-(1-(1-(propylsulfonyl)-4-(pyrid...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248667(2,4-dichloro-N-((4-(4-methylpyridin-2-yl)-1-(propy...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248059((S)-2-chloro-3,5-difluoro-N-(1-(1-(propylsulfonyl)...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121279(2-Amino-1-[2-(5-ethyl-1H-imidazol-2-yl)-2,3-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736Q7XPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248100((2,4-dichloro-N-((1-(propylsulfonyl)-4-(pyridin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248100((2,4-dichloro-N-((1-(propylsulfonyl)-4-(pyridin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248648(3,6-dichloro-2-fluoro-N-((1-(propylsulfonyl)-4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121284(2-Amino-1-[2-(5-methyl-1H-imidazol-2-yl)-2,3-dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736Q7XPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248646(2,6-dichloro-N-((1-(propylsulfonyl)-4-(pyridin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248653(2-chloro-N-((4-(6-methoxypyridin-2-yl)-1-(propylsu...)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248647(2-amino-6-chloro-N-((1-(propylsulfonyl)-4-(pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121282((S)-1-((S)-2-aminobutanoyl)-N-butylindoline-2-carb...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736Q7XPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248670(2,4-dichloro-N-((4-(6-methoxypyridin-2-yl)-1-(prop...)copy SMILEScopy InChI
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248125(2,4-dichloro-N-((1-methyl-1'-(propylsulfonyl)-2,4'...)copy SMILEScopy InChI
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248128(2,4-dichloro-N-((1-(2-fluoropropylsulfonyl)-4-(pyr...)copy SMILEScopy InChI
Affinity DataIC50: 9.70nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248681(2-chloro-N-((1-(propylsulfonyl)-4-(pyridin-2-yl)pi...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248013((S)-N-(1-(1-(propylsulfonyl)-4-(pyridin-2-yl)piper...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248097(2-(4-((2,4-dichlorobenzamido)methyl)-1-(propylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248665(CHEMBL517034 | N-((1-(propylsulfonyl)-4-(pyridin-2...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248644(2-methyl-N-((1-(propylsulfonyl)-4-(pyridin-2-yl)pi...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM15165(1-[1-({4-[3-phenyl-7-(2H-1,2,3,4-tetrazol-5-yl)qui...)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.5 T: 2°CAssay Description:Purified recombinant human Akt1, Akt2, and Akt3 proteins were monitored for kinase activity in the presence or absence of Akt inhibitors in a 96-well...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3CM4PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248094(CHEMBL460922 | N-((1-methyl-1'-(propylsulfonyl)-2,...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121280(2-Amino-1-[2-(5-methyl-1H-imidazol-2-yl)-2,3-dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736Q7XPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248063(2,4-dichloro-N-((4-(2-methoxyethyl)-1-(propylsulfo...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248099(2,4-dichloro-N-((4-(cyclopropylmethyl)-1-(propylsu...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248664(CHEMBL465426 | N-((1-(propylsulfonyl)-4-(pyridin-2...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetTripeptidyl-peptidase 2(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50121283(2-Amino-1-[2-(1H-imidazol-2-yl)-2,3-dihydro-indol-...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736Q7XPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248666(2-chloro-N-((4-(4-methylpyridin-2-yl)-1-(propylsul...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248098(CHEMBL462148 | N-((4-(azetidin-1-yl)-1-(propylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248126(2-chloro-3,5-difluoro-N-((1-methyl-1'-(propylsulfo...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248652(CHEMBL465129 | N-((4-(6-methoxypyridin-2-yl)-1-(pr...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248643(2-fluoro-N-((1-(propylsulfonyl)-4-(pyridin-2-yl)pi...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248668(CHEMBL463238 | N-((4-(6-methylpyridin-2-yl)-1-(pro...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM15167(1-[1-({4-[7-(2-methyl-2H-1,2,3,4-tetrazol-5-yl)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 55nMpH: 7.5 T: 2°CAssay Description:Purified recombinant human Akt1, Akt2, and Akt3 proteins were monitored for kinase activity in the presence or absence of Akt inhibitors in a 96-well...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3CM4PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248130(2,4-dichloro-N-((1-(ethylsulfonyl)-4-(pyridin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM15169(1-{1-[(4-{7-phenyl-1H-imidazo[4,5-g]quinoxalin-6-y...)copy SMILEScopy InChI
Affinity DataIC50: 58nMpH: 7.5 T: 2°CAssay Description:Purified recombinant human Akt1, Akt2, and Akt3 proteins were monitored for kinase activity in the presence or absence of Akt inhibitors in a 96-well...More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248095(2-chloro-N-((1-methyl-1'-(propylsulfonyl)-2,4'-bip...)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM15164(1-[1-({4-[3-phenyl-6-(2H-1,2,3,4-tetrazol-5-yl)qui...)copy SMILEScopy InChI
Affinity DataIC50: 63nMpH: 7.5 T: 2°CAssay Description:Purified recombinant human Akt1, Akt2, and Akt3 proteins were monitored for kinase activity in the presence or absence of Akt inhibitors in a 96-well...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3CM4PubMed
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM15164(1-[1-({4-[3-phenyl-6-(2H-1,2,3,4-tetrazol-5-yl)qui...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Purified recombinant human Akt1, Akt2, and Akt3 proteins were monitored for kinase activity in the presence or absence of Akt inhibitors in a 96-well...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3CM4PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248060(2,4-dichloro-N-((1-(propylsulfonyl)-4-(pyridin-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248162(2,4-dichloro-N-((1-(N,N-dimethylsulfamoyl)-4-(pyri...)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248061(2,4-dichloro-N-((1-(propylsulfonyl)-4-(pyridin-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM15168(1-{1-[(4-{7-phenyl-1H-pyrazolo[3,4-g]quinoxalin-6-...)copy SMILEScopy InChI
Affinity DataIC50: 85nMpH: 7.5 T: 2°CAssay Description:Purified recombinant human Akt1, Akt2, and Akt3 proteins were monitored for kinase activity in the presence or absence of Akt inhibitors in a 96-well...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3CM4PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248127(2,4-dichloro-N-((1-(2-hydroxypropylsulfonyl)-4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of Glyt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27V5NPubMed
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50248682(4-chloro-N-((1-(propylsulfonyl)-4-(pyridin-2-yl)pi...)copy SMILEScopy InChI
Affinity DataIC50: 103nMAssay Description:Inhibition of human glycine transporter 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124P3PubMed
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