Compile Data Set for Download or QSAR
Found 25 with Last Name = 'choi' and Initial = 'wi'
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50557170(CHEMBL4790492)copy SMILES
Affinity DataIC50: 42nMAssay Description:Inhibition of Tryptophan hydroxylase 1 (unknown origin) incubated for 4 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J106VMPubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50557173(CHEMBL4798791)copy SMILES
Affinity DataIC50: 49nMAssay Description:Inhibition of Tryptophan hydroxylase 1 (unknown origin) incubated for 4 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J106VMPubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50557172(CHEMBL4792465)copy SMILES
Affinity DataIC50: 60nMAssay Description:Inhibition of Tryptophan hydroxylase 1 (unknown origin) incubated for 4 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J106VMPubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50145648(LP-778902 | LX1032 | LX1606 | Telotristat | Xermel...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of Tryptophan hydroxylase 1 (unknown origin) incubated for 4 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J106VMPubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50557169(CHEMBL4760939)copy SMILES
Affinity DataIC50: 65nMAssay Description:Inhibition of Tryptophan hydroxylase 1 (unknown origin) incubated for 4 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J106VMPubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50508419(CHEMBL4471264)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibition of PDK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2F8HPubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50557171(CHEMBL4761240)copy SMILES
Affinity DataIC50: 120nMAssay Description:Inhibition of Tryptophan hydroxylase 1 (unknown origin) incubated for 4 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J106VMPubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50508420(CHEMBL4439097)copy SMILEScopy InChI
Affinity DataIC50: 143nMAssay Description:Inhibition of PDK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2F8HPubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50557168(CHEMBL4782978)copy SMILES
Affinity DataIC50: 166nMAssay Description:Inhibition of Tryptophan hydroxylase 1 (unknown origin) incubated for 4 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J106VMPubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50557165(CHEMBL4761947)copy SMILES
Affinity DataIC50: 483nMAssay Description:Inhibition of Tryptophan hydroxylase 1 (unknown origin) incubated for 4 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J106VMPubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50557166(CHEMBL4795848)copy SMILES
Affinity DataIC50: 490nMAssay Description:Inhibition of Tryptophan hydroxylase 1 (unknown origin) incubated for 4 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J106VMPubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50019143(CHEMBL511275 | US10683309, Example LP533401)copy SMILEScopy InChI
Affinity DataIC50: 583nMAssay Description:Inhibition of Tryptophan hydroxylase 1 (unknown origin) incubated for 4 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J106VMPubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50508421(CHEMBL4475200)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of PDK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2F8HPubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM227594(PS10)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:Inhibition of PDK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2F8HPubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50557167(CHEMBL4777453)copy SMILES
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of Tryptophan hydroxylase 1 (unknown origin) incubated for 4 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J106VMPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50508419(CHEMBL4471264)copy SMILEScopy InChI
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes assessed as reduction in phenacetin-O-deethylation by tandem mass spectrometry analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2F8HPubMed
TargetCytochrome P450 3A4/3A43/3A5/3A7(Homo sapiens (Human))
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50508419(CHEMBL4471264)copy SMILEScopy InChI
Affinity DataIC50: 3.66E+4nMAssay Description:Inhibition of CYP3A in human liver microsomes assessed as reduction in midazolam 1'-hydroxylation by tandem mass spectrometry analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2F8HPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50508419(CHEMBL4471264)copy SMILEScopy InChI
Affinity DataIC50: 4.24E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes assessed as reduction in omeprazole hydroxylation by tandem mass spectrometry analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2F8HPubMed
TargetTryptophan 5-hydroxylase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50145657(CHEBI:47069 | CHEMBL412813)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Tryptophan hydroxylase 1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J106VMPubMed
TargetUDP-glucuronosyltransferase 1A9(Homo sapiens (Human))
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50508419(CHEMBL4471264)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of UGT1A9 in human liver microsomes assessed as reduction in mycophenolic acid glucuronidation by tandem mass spectrometry analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2F8HPubMed
TargetUDP-glucuronosyltransferase 2B7(Homo sapiens (Human))
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50508419(CHEMBL4471264)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of UGT2B7 in human liver microsomes assessed as reduction in naloxone 3-glucuronidation by tandem mass spectrometry analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2F8HPubMed
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50508419(CHEMBL4471264)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of UGT1A1 in human liver microsomes assessed as reduction in SN-38 glucuronidation by tandem mass spectrometry analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2F8HPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50508419(CHEMBL4471264)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes assessed as reduction in tolbutamide 4-hydroxylation by tandem mass spectrometry analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2F8HPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50508419(CHEMBL4471264)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes assessed as reduction in dextromethorphan O-demethylation by tandem mass spectrometry analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2F8HPubMed
TargetUDP-glucuronosyltransferase 1A4(Homo sapiens (Human))
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50508419(CHEMBL4471264)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of UGT1A4 in human liver microsomes assessed as reduction in trifluoperazine N-glucuronidation by tandem mass spectrometry analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2F8HPubMed