Compile Data Set for Download or QSAR
Found 84 with Last Name = 'faraci' and Initial = 'ws'
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)copy SMILEScopy InChI
Affinity DataKi:  0.840nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMedDrugBank
TargetD(4) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069035((7R,9aS)-7-Phenoxymethyl-2-phenyl-octahydro-pyrido...)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069036((7S,9aS)-7-Phenoxymethyl-2-pyrimidin-2-yl-octahydr...)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069036((7S,9aS)-7-Phenoxymethyl-2-pyrimidin-2-yl-octahydr...)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069037((7R,9aS)-7-Phenoxymethyl-2-pyridin-2-yl-octahydro-...)copy SMILEScopy InChI
Affinity DataKi:  1.70nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069039((7S,9aS)-7-(4-Fluoro-phenoxymethyl)-2-(5-fluoro-py...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetProlyl endopeptidase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50279827(2-((S)-2-Formyl-pyrrolidine-1-carbonyl)-2,3-dihydr...)copy SMILEScopy InChI
Affinity DataKi:  2.40nM Kon:  0.000300M-1s-1 Koff:  1.40E+5s-1Assay Description:Compound was evaluated for the enzyme kinetic data (kon) for binding inhibition against Prolyl Endopeptidase (PEP)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ909F
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50058163(Butyl-[2,5-dimethyl-7-(2,4,6-trimethyl-phenyl)-7H-...)copy SMILEScopy InChI
Affinity DataKi:  2.70nMAssay Description:Binding affinity of the compound against [125I]-Try0-o-Corticotropin-releasing Factor to Corticotropin releasing hormone receptor 1 from ovineMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1JQPPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069048((7R,9aS)-7-(4-Fluoro-phenoxymethyl)-2-pyrimidin-2-...)copy SMILEScopy InChI
Affinity DataKi:  2.80nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetProlyl endopeptidase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50279825((1R,2S)-2-((S)-2-Formyl-pyrrolidine-1-carbonyl)-cy...)copy SMILEScopy InChI
Affinity DataKi:  3nM Kon:  0.00200M-1s-1 Koff:  7.00E+5s-1Assay Description:Compound was evaluated for the enzyme kinetic data (kon) for binding inhibition against Prolyl Endopeptidase (PEP)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ909F
TargetProlyl endopeptidase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50279826((1S,2S)-2-((S)-2-Formyl-pyrrolidine-1-carbonyl)-cy...)copy SMILEScopy InChI
Affinity DataKi:  3nM Kon:  0.000700M-1s-1 Koff:  2.30E+5s-1Assay Description:Compound was evaluated for the enzyme kinetic data (kon) for binding inhibition against Prolyl Endopeptidase (PEP)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ909F
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer Inc. Groton

Curated by ChEMBL
LigandPNGBDBM50081081(6-{4-[2-(4-Quinolin-8-yl-piperazin-1-yl)-ethyl]-ph...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Binding affinity of compound to human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XRPPubMed
TargetProlyl endopeptidase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50279825((1R,2S)-2-((S)-2-Formyl-pyrrolidine-1-carbonyl)-cy...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Compound was evaluated for binding inhibition against Prolyl Endopeptidase (PEP).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ909F
TargetD(4) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069034((7R,9aS)-2-(5-Chloro-pyridin-2-yl)-7-(4-fluoro-phe...)copy SMILEScopy InChI
Affinity DataKi:  3.20nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)copy SMILEScopy InChI
Affinity DataKi:  3.30nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069041((7R,9aS)-7-(4-Fluoro-phenoxymethyl)-2-(5-fluoro-py...)copy SMILEScopy InChI
Affinity DataKi:  3.40nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069047((7R,9aS)-7-Phenoxymethyl-2-pyrimidin-2-yl-octahydr...)copy SMILEScopy InChI
Affinity DataKi:  3.5nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069038(7-Phenoxymethyl-2-pyrimidin-2-yl-octahydro-pyrido[...)copy SMILEScopy InChI
Affinity DataKi:  3.80nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069042((7R,9aS)-7-(4-Fluoro-phenoxymethyl)-2-(4-fluoro-ph...)copy SMILEScopy InChI
Affinity DataKi:  5.30nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50081081(6-{4-[2-(4-Quinolin-8-yl-piperazin-1-yl)-ethyl]-ph...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Binding ability of compound to human Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XRPPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer Inc. Groton

Curated by ChEMBL
LigandPNGBDBM50081081(6-{4-[2-(4-Quinolin-8-yl-piperazin-1-yl)-ethyl]-ph...)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Binding affinity of compound to human 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XRPPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069043((7R,9aS)-7-(4-Methoxy-phenoxymethyl)-2-pyrimidin-2...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069049((7R,9aS)-7-(4-tert-Butyl-phenoxymethyl)-2-pyrimidi...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069036((7S,9aS)-7-Phenoxymethyl-2-pyrimidin-2-yl-octahydr...)copy SMILEScopy InChI
Affinity DataKi:  38nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069036((7S,9aS)-7-Phenoxymethyl-2-pyrimidin-2-yl-octahydr...)copy SMILEScopy InChI
Affinity DataKi:  38nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069044((7R,9aR)-7-(4-Fluoro-phenoxymethyl)-2-(5-fluoro-py...)copy SMILEScopy InChI
Affinity DataKi:  39nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069035((7R,9aS)-7-Phenoxymethyl-2-phenyl-octahydro-pyrido...)copy SMILEScopy InChI
Affinity DataKi:  44nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)copy SMILEScopy InChI
Affinity DataKi:  47nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMedDrugBank
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069039((7S,9aS)-7-(4-Fluoro-phenoxymethyl)-2-(5-fluoro-py...)copy SMILEScopy InChI
Affinity DataKi:  68nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069045((7S,9aR)-7-(4-Fluoro-phenoxymethyl)-2-(5-fluoro-py...)copy SMILEScopy InChI
Affinity DataKi:  106nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069046(4-((7R,9aS)-2-Pyrimidin-2-yl-octahydro-pyrido[1,2-...)copy SMILEScopy InChI
Affinity DataKi:  127nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50001884(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)copy SMILEScopy InChI
Affinity DataKi:  155nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMedDrugBank
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069038(7-Phenoxymethyl-2-pyrimidin-2-yl-octahydro-pyrido[...)copy SMILEScopy InChI
Affinity DataKi:  185nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069037((7R,9aS)-7-Phenoxymethyl-2-pyridin-2-yl-octahydro-...)copy SMILEScopy InChI
Affinity DataKi:  187nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069045((7S,9aR)-7-(4-Fluoro-phenoxymethyl)-2-(5-fluoro-py...)copy SMILEScopy InChI
Affinity DataKi:  195nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069042((7R,9aS)-7-(4-Fluoro-phenoxymethyl)-2-(4-fluoro-ph...)copy SMILEScopy InChI
Affinity DataKi:  206nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069046(4-((7R,9aS)-2-Pyrimidin-2-yl-octahydro-pyrido[1,2-...)copy SMILEScopy InChI
Affinity DataKi:  254nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069040(CHEMBL161899 | N-[4-((7R,9aS)-2-Pyrimidin-2-yl-oct...)copy SMILEScopy InChI
Affinity DataKi:  316nMAssay Description:In vitro binding affinity at human D4 dopamine receptor in CHO cells by [3H]-spiperone displacment.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Pfizer Inc. Groton

Curated by ChEMBL
LigandPNGBDBM50081082(2-(4-{2-[4-(6-Amino-pyridin-2-yl)-phenyl]-ethyl}-p...)copy SMILEScopy InChI
Affinity DataKi:  320nMAssay Description:Binding affinity of compound to m2 muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XRPPubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Pfizer Inc. Groton

Curated by ChEMBL
LigandPNGBDBM50081082(2-(4-{2-[4-(6-Amino-pyridin-2-yl)-phenyl]-ethyl}-p...)copy SMILEScopy InChI
Affinity DataKi:  590nMAssay Description:Binding ability of compound to m4 muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BC3XRPPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069043((7R,9aS)-7-(4-Methoxy-phenoxymethyl)-2-pyrimidin-2...)copy SMILEScopy InChI
Affinity DataKi:  918nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069040(CHEMBL161899 | N-[4-((7R,9aS)-2-Pyrimidin-2-yl-oct...)copy SMILEScopy InChI
Affinity DataKi:  948nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069044((7R,9aR)-7-(4-Fluoro-phenoxymethyl)-2-(5-fluoro-py...)copy SMILEScopy InChI
Affinity DataKi:  980nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069047((7R,9aS)-7-Phenoxymethyl-2-pyrimidin-2-yl-octahydr...)copy SMILEScopy InChI
Affinity DataKi:  1.14E+3nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069048((7R,9aS)-7-(4-Fluoro-phenoxymethyl)-2-pyrimidin-2-...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+3nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069049((7R,9aS)-7-(4-tert-Butyl-phenoxymethyl)-2-pyrimidi...)copy SMILEScopy InChI
Affinity DataKi:  1.72E+3nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069034((7R,9aS)-2-(5-Chloro-pyridin-2-yl)-7-(4-fluoro-phe...)copy SMILEScopy InChI
Affinity DataKi:  1.88E+3nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069041((7R,9aS)-7-(4-Fluoro-phenoxymethyl)-2-(5-fluoro-py...)copy SMILEScopy InChI
Affinity DataKi: >2.00E+3nMAssay Description:In vitro binding affinity against human D3 dopamine receptor in CHO cells using [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50069041((7R,9aS)-7-(4-Fluoro-phenoxymethyl)-2-(5-fluoro-py...)copy SMILEScopy InChI
Affinity DataKi: >3.31E+3nMAssay Description:In vitro binding affinity against human D2 dopamine receptor in CHO cells by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z941KPubMed
TargetCorticotropin-releasing factor receptor 2(RAT)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50058163(Butyl-[2,5-dimethyl-7-(2,4,6-trimethyl-phenyl)-7H-...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of binding of [125I]-Tyr0-sauvagine to Corticotropin releasing hormone receptor 2 (CRF2)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SJ1JQPPubMed
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