Compile Data Set for Download or QSAR
Found 22 with Last Name = 'borer' and Initial = 'x'
TargetInterleukin-2(Mus musculus)
Sandoz Pharma Ltd.

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:The compound was evaluated in vitro for the immunosuppressive activity in interleukin-2 by interleukin-2 reporter gene assay (IL2-RGA)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B79PubMed
TargetInterleukin-2(Mus musculus)
Sandoz Pharma Ltd.

Curated by ChEMBL
LigandPNGBDBM50422041(GECLOSPORIN)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:The compound was evaluated in vitro for the immunosuppressive activity in interleukin-2 by interleukin-2 reporter gene assay (IL2-RGA)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B79PubMed
TargetInterleukin-2(Mus musculus)
Sandoz Pharma Ltd.

Curated by ChEMBL
LigandPNGBDBM50033061(27-Hydroxymethyl-33-(1-hydroxy-2-methyl-hex-4-enyl...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:The compound was evaluated in vitro for the immunosuppressive activity in interleukin-2 by interleukin-2 reporter gene assay (IL2-RGA)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B79PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Sandoz Pharma Ltd.

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:In vitro binding affinity of the compound against cyclophilin A by rotamase assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B79PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Sandoz Pharma Ltd.

Curated by ChEMBL
LigandPNGBDBM50033061(27-Hydroxymethyl-33-(1-hydroxy-2-methyl-hex-4-enyl...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:In vitro binding affinity of the compound against cyclophilin A by rotamase assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B79PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Sandoz Pharma Ltd.

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:In vitro binding affinity of the compound against cyclophilin A by ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B79PubMed
TargetInterleukin-2(Mus musculus)
Sandoz Pharma Ltd.

Curated by ChEMBL
LigandPNGBDBM50033058(33-(1-Hydroxy-2-methyl-hex-4-enyl)-30-(3-hydroxy-p...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:The compound was evaluated in vitro for the immunosuppressive activity in interleukin-2 by interleukin-2 reporter gene assay (IL2-RGA)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B79PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Sandoz Pharma Ltd.

Curated by ChEMBL
LigandPNGBDBM50033061(27-Hydroxymethyl-33-(1-hydroxy-2-methyl-hex-4-enyl...)copy SMILEScopy InChI
Affinity DataIC50: 93nMAssay Description:In vitro binding affinity of the compound against cyclophilin A by ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B79PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
NOVARTIS Pharma, Inc.

LigandPNGBDBM85304(Alpha-cyano-beta-hydroxy enamide, 5)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Spectrophotometric assay using crude human, recombinant DHODHase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W37TVH
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
NOVARTIS Pharma, Inc.

LigandPNGBDBM14712((2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Spectrophotometric assay using crude human, recombinant DHODHase.More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Sandoz Pharma Ltd.

Curated by ChEMBL
LigandPNGBDBM50033058(33-(1-Hydroxy-2-methyl-hex-4-enyl)-30-(3-hydroxy-p...)copy SMILEScopy InChI
Affinity DataIC50: 256nMAssay Description:In vitro binding affinity of the compound against cyclophilin A by rotamase assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B79PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Sandoz Pharma Ltd.

Curated by ChEMBL
LigandPNGBDBM50422041(GECLOSPORIN)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:In vitro binding affinity of the compound against cyclophilin A by ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B79PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Sandoz Pharma Ltd.

Curated by ChEMBL
LigandPNGBDBM50422041(GECLOSPORIN)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:In vitro binding affinity of the compound against cyclophilin A by ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B79PubMed
TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Sandoz Pharma Ltd.

Curated by ChEMBL
LigandPNGBDBM50033058(33-(1-Hydroxy-2-methyl-hex-4-enyl)-30-(3-hydroxy-p...)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:In vitro binding affinity of the compound against cyclophilin A by ELISAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27W6B79PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
NOVARTIS Pharma, Inc.

LigandPNGBDBM50054587((Z)-2-Cyano-N-(4-cyano-phenyl)-3-cyclopropyl-3-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Spectrophotometric assay using crude human, recombinant DHODHase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W37TVH
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
NOVARTIS Pharma, Inc.

LigandPNGBDBM85302(Alpha-cyano-beta-hydroxy enamide, 3)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Spectrophotometric assay using crude human, recombinant DHODHase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W37TVH
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
NOVARTIS Pharma, Inc.

LigandPNGBDBM85301(Alpha-cyano-beta-hydroxy enamide, 2)copy SMILEScopy InChI
Affinity DataIC50: 1.52E+4nMAssay Description:Spectrophotometric assay using crude human, recombinant DHODHase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W37TVH
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
NOVARTIS Pharma, Inc.

LigandPNGBDBM85303(Alpha-cyano-beta-hydroxy enamide, 4)copy SMILEScopy InChI
Affinity DataIC50: 1.62E+4nMAssay Description:Spectrophotometric assay using crude human, recombinant DHODHase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W37TVH
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
NOVARTIS Pharma, Inc.

LigandPNGBDBM85307(Tetrahydrofuranyl derivative, 7 (E))copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Spectrophotometric assay using crude human, recombinant DHODHase.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W37TVH
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
NOVARTIS Pharma, Inc.

LigandPNGBDBM85306(Tetrahydropyranyl derivative, 8 (Z))copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Spectrophotometric assay using crude human, recombinant DHODHase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W37TVH
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
NOVARTIS Pharma, Inc.

LigandPNGBDBM85305(Tetrahydrofuranyl derivative, 7 (Z))copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Spectrophotometric assay using crude human, recombinant DHODHase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W37TVH
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
NOVARTIS Pharma, Inc.

LigandPNGBDBM85308(Tetrahydropyranyl derivative, 8 (E))copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Spectrophotometric assay using crude human, recombinant DHODHase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W37TVH