Compile Data Set for Download or QSAR
Found 527 with Last Name = 'min' and Initial = 'x'
TargetEukaryotic translation initiation factor 4E(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50316302(((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-...)copy SMILEScopy InChI
Affinity DataKi:  28nMAssay Description:Competitive inhibition of [3H]m7-GTP binding to human FLAG-His6 tagged eIF4E expressed in Escherichia coli by scintillation proximity assayMore data for this Ligand-Target Pair
TargetSphingosine kinase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50343835((S)-1-(4-(4-(3-(2-Cyclohexylethyl)phenyl)oxazol-2-...)copy SMILEScopy InChI
Affinity DataKi:  50nMAssay Description:Inhibition of purified human SphK1 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736SB3PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50229787((4S,5R)-Nutlin-3 | (rac)-(4,5-bis(4-chlorophenyl)-...)copy SMILEScopy InChI
Affinity DataKi:  90nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition of interaction with p53 after 1 hr by fluorescence polarization binding assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50018554(CHEMBL3290682)copy SMILEScopy InChI
Affinity DataKi:  90nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition of interaction with p53 after 1 hr by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3P22PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50018543(CHEMBL3290677)copy SMILEScopy InChI
Affinity DataKi:  90nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition of interaction with p53 after 1 hr by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3P22PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50018555(CHEMBL3290683)copy SMILEScopy InChI
Affinity DataKi:  150nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition of interaction with p53 after 1 hr by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3P22PubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50438113(CHEMBL1092481)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Inhibition of purified human SphK1 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736SB3PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50018541(CHEMBL2180122)copy SMILEScopy InChI
Affinity DataKi:  260nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition of interaction with p53 after 1 hr by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3P22PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50018540(CHEMBL3290675)copy SMILEScopy InChI
Affinity DataKi:  320nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition of interaction with p53 after 1 hr by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3P22PubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50312869(4-(4-(4-chlorophenyl)thiazol-2-ylamino)phenol | CH...)copy SMILEScopy InChI
Affinity DataKi:  500nMAssay Description:Inhibition of purified human SphK1 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSphingosine kinase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50438113(CHEMBL1092481)copy SMILEScopy InChI
Affinity DataKi:  500nMAssay Description:Inhibition of purified human SphK2 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736SB3PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50018537(CHEMBL3290672)copy SMILEScopy InChI
Affinity DataKi:  710nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition of interaction with p53 after 1 hr by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3P22PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50018536(CHEMBL3290671)copy SMILEScopy InChI
Affinity DataKi:  720nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition of interaction with p53 after 1 hr by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3P22PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50018534(CHEMBL3290670)copy SMILEScopy InChI
Affinity DataKi:  1.37E+3nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition of interaction with p53 after 1 hr by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3P22PubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50299323((S)-2-amino-4-hydroxy-N-(4-octylphenyl)butanamide ...)copy SMILEScopy InChI
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of purified human SphK1 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736SB3PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50018539(CHEMBL3290674)copy SMILEScopy InChI
Affinity DataKi:  1.72E+3nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition of interaction with p53 after 1 hr by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3P22PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50018547(CHEMBL3290678)copy SMILEScopy InChI
Affinity DataKi:  3.02E+3nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition of interaction with p53 after 1 hr by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3P22PubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50343835((S)-1-(4-(4-(3-(2-Cyclohexylethyl)phenyl)oxazol-2-...)copy SMILEScopy InChI
Affinity DataKi:  4.20E+3nMAssay Description:Inhibition of purified human SphK2 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736SB3PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50018542(CHEMBL3290676)copy SMILEScopy InChI
Affinity DataKi:  8.18E+3nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition of interaction with p53 after 1 hr by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3P22PubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50393642(CHEMBL2158685)copy SMILEScopy InChI
Affinity DataKi:  9.80E+3nMAssay Description:Inhibition of purified human SphK2 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736SB3PubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50438114(CHEMBL2409758)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of purified human SphK1 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736SB3PubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50299323((S)-2-amino-4-hydroxy-N-(4-octylphenyl)butanamide ...)copy SMILEScopy InChI
Affinity DataKi:  3.10E+4nMAssay Description:Inhibition of purified human SphK2 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736SB3PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50018552(CHEMBL3290681)copy SMILEScopy InChI
Affinity DataKi:  3.77E+4nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition of interaction with p53 after 1 hr by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3P22PubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50438114(CHEMBL2409758)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of purified human SphK2 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736SB3PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50018549(CHEMBL3290680)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition of interaction with p53 after 1 hr by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3P22PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50018548(CHEMBL3290679)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition of interaction with p53 after 1 hr by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3P22PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50018538(CHEMBL3290673)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition of interaction with p53 after 1 hr by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3P22PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50018535(CHEMBL3290669)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as inhibition of interaction with p53 after 1 hr by fluorescence polarization binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3P22PubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Merck & Co. Inc

Curated by ChEMBL
LigandPNGBDBM50280116(CHEMBL4177355)copy SMILEScopy InChI
Affinity DataIC50: 0.0120nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Val-Ser-Gln-Asn-(beta-naphtyl)Ala-Pro-Ile-Val as substrate preincubated for 30 mins f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X57PubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Merck & Co. Inc

Curated by ChEMBL
LigandPNGBDBM8125((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)copy SMILEScopy InChI
Affinity DataIC50: 0.0130nMAssay Description:Inhibition of GAR transformylase from Lactobacillus caseiMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Merck & Co. Inc

Curated by ChEMBL
LigandPNGBDBM13934(Atazanavir | BMS 232632 | CGP 73547 | CHEMBL1163 |...)copy SMILEScopy InChI
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Val-Ser-Gln-Asn-(beta-naphtyl)Ala-Pro-Ile-Val as substrate preincubated for 30 mins f...More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Merck & Co. Inc

Curated by ChEMBL
LigandPNGBDBM13934(Atazanavir | BMS 232632 | CGP 73547 | CHEMBL1163 |...)copy SMILEScopy InChI
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50450601(CHEMBL4162835)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZB0PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50450604(CHEMBL4163942)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZB0PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50450580(CHEMBL4169884)copy SMILEScopy InChI
Affinity DataIC50: 0.260nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZB0PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50450584(CHEMBL4173743)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZB0PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50450603(CHEMBL4159473)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZB0PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50450606(CHEMBL4175995)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZB0PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50450583(CHEMBL4174312)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZB0PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50450593(CHEMBL4164272)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZB0PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50450596(CHEMBL4168880)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZB0PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50450602(CHEMBL4167379)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZB0PubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Merck & Co. Inc

Curated by ChEMBL
LigandPNGBDBM50190623(CHEMBL3828743)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Val-Ser-Gln-Asn-(beta-naphtyl)Ala-Pro-Ile-Val as substrate preincubated for 30 mins f...More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50450581(CHEMBL4159169)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZB0PubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Merck & Co. Inc

Curated by ChEMBL
LigandPNGBDBM50190623(CHEMBL3828743)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50450615(CHEMBL4167376)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZB0PubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50244890(CHEMBL472535 | N-(2-fluorophenyl)-4-(3-phenyl-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2P9MPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50450612(CHEMBL4160269)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZB0PubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50339871((S)-3-(1-(4-(5-chlorothiophen-2-yl)pyrimidin-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human FAAH assessed as hydrolysis of anandamidoaminomethylcumarinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2P9MPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50450585(CHEMBL4166895)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells at holding potential of -125 mV after 10 mins by patchxpress-based electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZB0PubMed
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