Compile Data Set for Download or QSAR
Found 44 with Last Name = 'cheng' and Initial = 'xr'
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033887(CHEMBL3358611)copy SMILEScopy InChI
Affinity DataKi:  146nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033944(CHEMBL3358598)copy SMILEScopy InChI
Affinity DataKi:  4.77E+3nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033946(CHEMBL3358596)copy SMILEScopy InChI
Affinity DataKi:  6.62E+3nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Toronto at Mississauga

Curated by ChEMBL
LigandPNGBDBM50446146(CHEMBL3108909)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nMAssay Description:Competitive binding affinity to STAT3 SH2 domain (unknown origin) assessed as inhibition of interaction with FAMpYLPQTV after 15 to 30 mins by fluore...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D2202PPubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Toronto at Mississauga

Curated by ChEMBL
LigandPNGBDBM50446145(CHEMBL3108910)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nMAssay Description:Competitive binding affinity to STAT3 SH2 domain (unknown origin) assessed as inhibition of interaction with FAMpYLPQTV after 15 to 30 mins by fluore...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D2202PPubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Toronto at Mississauga

Curated by ChEMBL
LigandPNGBDBM50446144(CHEMBL3108911)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nMAssay Description:Competitive binding affinity to STAT3 SH2 domain (unknown origin) assessed as inhibition of interaction with FAMpYLPQTV after 15 to 30 mins by fluore...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D2202PPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033888(CHEMBL3358610)copy SMILEScopy InChI
Affinity DataKi:  1.15E+4nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033890(CHEMBL3358608)copy SMILEScopy InChI
Affinity DataKi:  1.24E+4nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033895(CHEMBL3358604)copy SMILEScopy InChI
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50034006(CHEMBL3358591)copy SMILEScopy InChI
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50034005(CHEMBL3358592)copy SMILEScopy InChI
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033993(CHEMBL3358593)copy SMILEScopy InChI
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033963(CHEMBL3358594)copy SMILEScopy InChI
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033947(CHEMBL3358595)copy SMILEScopy InChI
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033945(CHEMBL3358597)copy SMILEScopy InChI
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033943(CHEMBL3358599)copy SMILEScopy InChI
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50034036(CHEMBL3358588)copy SMILEScopy InChI
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50034008(CHEMBL3358589)copy SMILEScopy InChI
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50034080(CHEMBL3358587)copy SMILEScopy InChI
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033889(CHEMBL3358609)copy SMILEScopy InChI
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50034007(CHEMBL3358590)copy SMILEScopy InChI
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033891(CHEMBL3358607)copy SMILEScopy InChI
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033892(CHEMBL3358606)copy SMILEScopy InChI
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033893(CHEMBL3358605)copy SMILEScopy InChI
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033896(CHEMBL3358603)copy SMILEScopy InChI
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033897(CHEMBL3358602)copy SMILEScopy InChI
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033939(CHEMBL3358601)copy SMILEScopy InChI
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033940(CHEMBL3358600)copy SMILEScopy InChI
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of STAT5B SH2 domain (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Toronto at Mississauga

Curated by ChEMBL
LigandPNGBDBM50033887(CHEMBL3358611)copy SMILEScopy InChI
Affinity DataKi:  1.44E+5nMAssay Description:Inhibition of STAT3 (unknown origin)-5-FAM-GpYLVLDKW interaction compound treated for 15 mins by fluorescent polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute of Pharmacology and Toxicology

Curated by ChEMBL
LigandPNGBDBM16034(1-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phen...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute of Pharmacology and Toxicology

Curated by ChEMBL
LigandPNGBDBM16034(1-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phen...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human BACE1 proteolytic activityMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute of Pharmacology and Toxicology

Curated by ChEMBL
LigandPNGBDBM16034(1-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phen...)copy SMILEScopy InChI
Affinity DataIC50: 19.9nMAssay Description:Inhibition of recombinant human BACE1 using Eu-CEVNLDAEFK-Qsy7 as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute of Pharmacology and Toxicology

Curated by ChEMBL
LigandPNGBDBM16034(1-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phen...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of BACE1 expressed in HEK293T cells co-transfected APP with NFEV mutation at proteolytic site by sAPP_NF cell based assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute of Pharmacology and Toxicology

Curated by ChEMBL
LigandPNGBDBM16034(1-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phen...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant human BACE1 expressed in CHO cells co-transfected with human APP with Swedish mutation assessed as amyloid beta1-40 secreti...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute of Pharmacology and Toxicology

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin gallate | (-)-Epigallocatechi...)copy SMILEScopy InChI
Affinity DataIC50: 757nMAssay Description:Inhibition of recombinant human BACE1 using Eu-CEVNLDAEFK-Qsy7 as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7VGCPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute of Pharmacology and Toxicology

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin gallate | (-)-Epigallocatechi...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of BACE1 using Rh-EVNLDAEFK-Quencher as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7VGCPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute of Pharmacology and Toxicology

Curated by ChEMBL
LigandPNGBDBM50364303(CHEMBL1952315)copy SMILEScopy InChI
Affinity DataIC50: 2.27E+3nMAssay Description:Inhibition of recombinant human BACE1 using Eu-CEVNLDAEFK-Qsy7 as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7VGCPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute of Pharmacology and Toxicology

Curated by ChEMBL
LigandPNGBDBM50364304(CHEMBL1952316)copy SMILEScopy InChI
Affinity DataIC50: 2.81E+3nMAssay Description:Inhibition of recombinant human BACE1 using Eu-CEVNLDAEFK-Qsy7 as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7VGCPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute of Pharmacology and Toxicology

Curated by ChEMBL
LigandPNGBDBM50364305(CHEMBL1952317)copy SMILEScopy InChI
Affinity DataIC50: 3.84E+3nMAssay Description:Inhibition of recombinant human BACE1 using Eu-CEVNLDAEFK-Qsy7 as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7VGCPubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Toronto at Mississauga

Curated by ChEMBL
LigandPNGBDBM50033887(CHEMBL3358611)copy SMILEScopy InChI
Affinity DataKd:  287nMAssay Description:Binding affinity to full-length His-tagged STAT3 (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute of Pharmacology and Toxicology

Curated by ChEMBL
LigandPNGBDBM16034(1-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phen...)copy SMILEScopy InChI
Affinity DataEC50:  43nMAssay Description:Inhibition of BACE1 expressed in HEK293T cells co-transfected APP with NFEV mutation at proteolytic site assessed as amyloid EV40 secretionMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University of Toronto at Mississauga

Curated by ChEMBL
LigandPNGBDBM50446146(CHEMBL3108909)copy SMILEScopy InChI
Affinity DataKd:  300nMAssay Description:Binding affinity to His-tagged STAT3 (unknown origin) by SPR spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D2202PPubMed
TargetSignal transducer and activator of transcription 5A(Homo sapiens (Human))
University of Toronto at Mississauga

Curated by ChEMBL
LigandPNGBDBM50446146(CHEMBL3108909)copy SMILEScopy InChI
Affinity DataKd:  464nMAssay Description:Binding affinity to His-tagged STAT5 (unknown origin) by SPR spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D2202PPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50033887(CHEMBL3358611)copy SMILEScopy InChI
Affinity DataKd:  42nMAssay Description:Binding affinity to full-length His-tagged STAT5B (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2BJJPubMed