Compile Data Set for Download or QSAR
Found 577 with Last Name = 'bekkali' and Initial = 'y'
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)copy SMILEScopy InChI
Affinity DataIC50: 0.510nMAssay Description:Agonist activity at glucocorticoid receptor in HFF assessed as inhibition of IL1-induced IL-6 production after 18 to 24 hrsMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50356050(CHEMBL1911650)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Displacement of tetramethylrhodamine-labeled Dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus infected insect ce...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4J51PubMed
TargetCathepsin S(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50208836((R)-N-((R)-3-cyano-1-cyclohexylpyrrolidin-3-yl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X57G7PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50356060(CHEMBL1911664)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Displacement of tetramethylrhodamine-labeled Dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus infected insect ce...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4J51PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of TAMRA labeled Dexamethasone at human glucocorticoid receptor in insect cellMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201093(1-[4-(4-fluoro-2-hydroxyphenyl)-2-hydroxy-4-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethosone binding to GR by FP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2PTBPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201099(4-(2,3-dihydrobenzofuran-7-yl)-2-hydroxy-4-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethosone binding to GR by FP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2PTBPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethosone binding to GR by FP assayMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM18207((1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dih...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Displacement of tetramethylrhodamine-labeled Dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus infected insect ce...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50356050(CHEMBL1911650)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Agonist activity at glucocorticoid receptor in HFF assessed as inhibition of IL1-induced IL-6 production after 18 to 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4J51PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201100(1-[4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethosone binding to GR by FP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2PTBPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201081(1-[4-(2,3-dihydrobenzofuran-7-yl)-2-hydroxy-4-meth...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethosone binding to GR by FP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2PTBPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201090(1-[4-(5-fluoro-2-hydroxyphenyl)-2-hydroxy-4-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethosone binding to GR by FP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2PTBPubMed
TargetCathepsin S(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50121542(CHEMBL155560 | Thiophene-2-carboxylic acid {1-[(be...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration against human recombinant Cathepsin S expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26XG7PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50356044(CHEMBL1911644)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of tetramethylrhodamine-labeled Dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus infected insect ce...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4J51PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50356059(CHEMBL1911662)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of tetramethylrhodamine-labeled Dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus infected insect ce...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4J51PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50356063(CHEMBL1911661)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of tetramethylrhodamine-labeled Dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus infected insect ce...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4J51PubMed
TargetCathepsin S(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50121562(CHEMBL153239 | Morpholine-4-carboxylic acid [1-(1-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration against human recombinant Cathepsin S expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26XG7PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201096(1-[2-hydroxy-4-(2-hydroxyphenyl)-4-methyl-2-(trifl...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethosone binding to GR by FP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2PTBPubMed
TargetCathepsin S(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50121554(CHEMBL356155 | N-{1-[(Benzyloxymethyl-cyano-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibitory concentration against human recombinant Cathepsin S expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26XG7PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50356042(CHEMBL1911548)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Agonist activity at glucocorticoid receptor in HFF assessed as inhibition of IL1-induced IL-6 production after 18 to 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4J51PubMed
TargetCathepsin S(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50121549(CHEMBL347111 | Morpholine-4-carboxylic acid {1-[(b...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibitory concentration against human recombinant Cathepsin S expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26XG7PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50356062(CHEMBL1911660)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Displacement of tetramethylrhodamine-labeled Dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus infected insect ce...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4J51PubMed
TargetCathepsin S(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50121575(CHEMBL356442 | Morpholine-4-carboxylic acid (1-{[c...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration against human recombinant Cathepsin S expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26XG7PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50356036(CHEMBL1911542)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Agonist activity at glucocorticoid receptor in HFF assessed as inhibition of IL1-induced IL-6 production after 18 to 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4J51PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50356057(CHEMBL1911657)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Agonist activity at glucocorticoid receptor in HFF assessed as inhibition of IL1-induced IL-6 production after 18 to 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4J51PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM19190((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Agonist activity at glucocorticoid receptor in HFF assessed as inhibition of IL1-induced IL-6 production after 18 to 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4J51PubMedDrugBank
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219447(2-(4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Displacement of TAMRA labeled Dexamethasone at human glucocorticoid receptor in insect cellMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73FJ2PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201104(4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-N-...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethosone binding to GR by FP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2PTBPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201082(1-[2-hydroxy-4-(2-hydroxy-5-methylphenyl)-4-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethosone binding to GR by FP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2PTBPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50356049(CHEMBL1911649)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Displacement of tetramethylrhodamine-labeled Dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus infected insect ce...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4J51PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50356044(CHEMBL1911644)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Agonist activity at glucocorticoid receptor in HFF assessed as inhibition of IL1-induced IL-6 production after 18 to 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4J51PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201104(4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-N-...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Displacement of TAMRA labeled Dexamethasone at human glucocorticoid receptor in insect cellMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73FJ2PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50356056(CHEMBL1911656)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Displacement of tetramethylrhodamine-labeled Dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus infected insect ce...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4J51PubMed
TargetCathepsin S(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50121581(CHEMBL150253 | Morpholine-4-carboxylic acid (1-{[(...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibitory concentration against human recombinant Cathepsin S expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26XG7PubMed
TargetCathepsin S(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50121569(CHEMBL153783 | Morpholine-4-carboxylic acid {1-[(b...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibitory concentration against human recombinant Cathepsin S expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26XG7PubMed
TargetCathepsin S(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50121545(CHEMBL149523 | Morpholine-4-carboxylic acid (1-{[(...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibitory concentration against human recombinant Cathepsin S expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26XG7PubMed
TargetCathepsin S(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50121544(CHEMBL153248 | Pyrazine-2-carboxylic acid {1-[(ben...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibitory concentration against human recombinant Cathepsin S expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26XG7PubMed
TargetCathepsin S(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50121543(CHEMBL435440 | Morpholine-4-carboxylic acid {1-[(c...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibitory concentration against human recombinant Cathepsin S expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26XG7PubMed
TargetCathepsin S(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50121561(CHEMBL356167 | Morpholine-4-carboxylic acid (1-{[(...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibitory concentration against human recombinant Cathepsin S expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26XG7PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201094(1-[4-(5-fluoro-2-methylphenyl)-2-hydroxy-4-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethosone binding to GR by FP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2PTBPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50356055(CHEMBL1911655)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Agonist activity at glucocorticoid receptor in HFF assessed as inhibition of IL1-induced IL-6 production after 18 to 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4J51PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201086(CHEMBL216273 | cis-1-[4-(5-fluoro-2-methoxyphenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethosone binding to GR by FP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2PTBPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201109(1-[4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethosone binding to GR by FP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2PTBPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50356036(CHEMBL1911542)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Displacement of tetramethylrhodamine-labeled Dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus infected insect ce...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4J51PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50356057(CHEMBL1911657)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Displacement of tetramethylrhodamine-labeled Dexamethasone from human recombinant glucocorticoid receptor expressed in baculovirus infected insect ce...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4J51PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201083(1-[2-hydroxy-4-(5-methoxy-2-methylphenyl)-4-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of tetramethylrhodamine labeled dexamethosone binding to GR by FP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2PTBPubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50356049(CHEMBL1911649)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Agonist activity at glucocorticoid receptor in HFF assessed as inhibition of IL1-induced IL-6 production after 18 to 24 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CV4J51PubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219457(4-(4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Displacement of TAMRA labeled Dexamethasone at human glucocorticoid receptor in insect cellMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73FJ2PubMed
TargetCathepsin S(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals Inc.

Curated by ChEMBL
LigandPNGBDBM50121558(CHEMBL152940 | Morpholine-4-carboxylic acid (1-{[c...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibitory concentration against human recombinant Cathepsin S expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P26XG7PubMed
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