Compile Data Set for Download or QSAR
Found 122 with Last Name = 'hayase' and Initial = 'y'
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50189733(CHEMBL379629 | ethyl 3-(N-benzyl-N-methylaminometh...)copy SMILEScopy InChI
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50189716(CHEMBL210294 | ethyl 3-(N-benzyl-N-methylaminometh...)copy SMILEScopy InChI
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50189704(3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...)copy SMILEScopy InChI
Affinity DataIC50: 0.0700nMAssay Description:Inhibition of LHRH-stimulated arachidonic acid release in CHO cells expressing human LHRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50189703(CHEMBL208812 | N-(4-(7-(2,6-difluorobenzyl)-5-benz...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50189701(3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50189704(3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50189730(CHEMBL210709 | ethyl 3-(N-benzyl-N-methylaminometh...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50189701(3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Inhibition of LHRH-stimulated arachidonic acid release in CHO cells expressing human LHRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50067485(3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:The Compound was tested for the concentration to inhibit 50% of [125 I ]leuprorelin binding to the cloned human Leutinizing releasing hormone recepto...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5V19PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50189704(3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [125I]leuprorelin binding to monkey recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50189707(3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50189723(CHEMBL540109 | ethyl 3-(N-benzyl-N-methylaminometh...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50189727(CHEMBL211503 | N-(4-(7-(2,6-difluorobenzyl)-3-((be...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50189720(3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50067485(3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50369395(ELIGARD | LEUPROLIDE)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50369395(ELIGARD | LEUPROLIDE)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:The Compound was tested for the concentration to inhibit 50% of [125 I ]leuprorelin binding to the cloned human Leutinizing releasing hormone recepto...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5V19PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115988(3-[(Benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:In vitro inhibition of specific [125I]-leuprorelin binding to the cloned human LHRH receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2G32PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115989(3-[(Benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibition of specific [125I]-leuprorelin binding to the cloned human LHRH receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2G32PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50189713(3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50189712(CHEMBL379198 | ethyl 3-(N-benzyl-N-methylaminometh...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50189736(3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50369395(ELIGARD | LEUPROLIDE)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:The compound was tested for the concentration to inhibit 50% of [125 I]leuprorelin binding to Leutinizing releasing hormone receptor in the membrane ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5V19PubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50369395(ELIGARD | LEUPROLIDE)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of [125I]leuprorelin binding to rat anterior pituitary LHRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115998(3-[(Benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:In vitro inhibition of specific [125I]-leuprorelin binding to the cloned human LHRH receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2G32PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50067485(3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of LHRH-stimulated arachidonic acid release in CHO cells expressing human LHRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50189740(CHEMBL210888 | ethyl 7-benzyl-3-((benzyl(methyl)am...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115995(3-[(Benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:In vitro inhibition of specific [125I]-leuprorelin binding to the cloned human LHRH receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2G32PubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50369395(ELIGARD | LEUPROLIDE)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:The compound was tested for the concentration to inhibit 50% of [125 I]leuprorelin binding to Leutinizing releasing hormone receptor the membrane fra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5V19PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50369395(ELIGARD | LEUPROLIDE)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of [125I]leuprorelin binding to monkey anterior pituitary LHRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50189701(3-(N-benzyl-N-methylaminomethyl)-7-(2,6-difluorobe...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of [125I]leuprorelin binding to monkey recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50189734(CHEMBL264121 | ethyl 2-(4-benzamidophenyl)-7-benzy...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50067485(3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of [125I]leuprorelin binding to monkey recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50189726(CHEMBL264574 | ethyl 3-(N-benzyl-N-methylaminometh...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50189728(CHEMBL211098 | ethyl 2-(4-acetamidophenyl)-7-benzy...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31587(oxadiazole derivative, 20x)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31586(oxadiazole derivative, 20w)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115994(3-[(Benzyl-methyl-amino)-methyl]-8-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of specific [125I]-leuprorelin binding to the cloned human LHRH receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2G32PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115991(2-(4-Acryloylamino-phenyl)-3-[(benzyl-methyl-amino...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of specific [125I]-leuprorelin binding to the cloned human LHRH receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2G32PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31578(oxadiazole derivative, 20o)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31584(oxadiazole derivative, 20u)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50067488(2-(4-Amino-phenyl)-3-[(benzyl-methyl-amino)-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:The Compound was tested for the concentration to inhibit 50% of [125 I ]leuprorelin binding to the cloned human Leutinizing releasing hormone recepto...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5V19PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50067485(3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of [125I]leuprorelin binding to monkey anterior pituitary LHRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50067485(3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:The compound was tested for the concentration to inhibit 50% of [125 I]leuprorelin binding to Leutinizing releasing hormone receptor the membrane fra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5V19PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31577(oxadiazole derivative, 20n)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50115992(3-[(Benzyl-methyl-amino)-methyl]-2-[4-(cyclopropan...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:In vitro inhibition of specific [125I]-leuprorelin binding to the cloned human LHRH receptor expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2G32PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.

LigandPNGBDBM31572(oxadiazole derivative, 20m)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMpH: 7.5 T: 2°CAssay Description:Human GSK-3beta was expressed as the N-terminal FLAG-tagged protein using a baculovirus expression system. The kinase assay was was conducted in a 96...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2STZPubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50422274(GONADORELIN | Human gonadoliberin-i)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:The compound was tested for the concentration to inhibit 50% of [125 I]leuprorelin binding to Leutinizing releasing hormone receptor the membrane fra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CR5V19PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50189708((S)-1-((S)-2-((S)-2-(2-((S)-2-((S)-2-((S)-2-((S)-3...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of [125I]leuprorelin binding to monkey anterior pituitary LHRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50067484(3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ33G8PubMed
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