Compile Data Set for Download or QSAR
Found 112 with Last Name = 'matsushita' and Initial = 'y'
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50438462(CHEMBL2414623)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as reduction of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9DHVPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50438467(CHEMBL2414618)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as reduction of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9DHVPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50446188(CHEMBL3109017)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50346265((2R,3R,4S,5S,6R)-2-(3-(4-cyclopropylbenzyl)-4-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50438463(CHEMBL2414622)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as reduction of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9DHVPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50446186(CHEMBL3109016)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50438465(CHEMBL2414620)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as reduction of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9DHVPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50438460(CHEMBL2414617)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as reduction of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9DHVPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50446185(CHEMBL3109015)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50386885(CANAGLIFLOZIN | CANAGLIFLOZIN HYDRATE | US10752604...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as reduction of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50438464(CHEMBL2414621)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as reduction of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9DHVPubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50024714(2-(4-Carboxymethyl-5-oxo-3-thiophen-2-yl-[1,4]thia...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibitory activity against rabbit lung Angiotensin I converting enzyme with 5 mM hippurylhistidylleucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NMJPubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50023299(2-(1-Carboxymethyl-2-oxo-6-phenyl-azepan-3-ylamino...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Concentration required for 50% inhibition of rabbit lung Angiotensin I converting enzyme with 5 mM hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75GWHPubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50023298(2-(4-Carboxymethyl-5-oxo-3-phenyl-[1,4]thiazepan-6...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Concentration required for 50% inhibition of rabbit lung Angiotensin I converting enzyme with 5 mM hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75GWHPubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50023298(2-(4-Carboxymethyl-5-oxo-3-phenyl-[1,4]thiazepan-6...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibitory activity against rabbit lung Angiotensin I converting enzyme with 5 mM hippurylhistidylleucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NMJPubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50024710(2-(4-Carboxymethyl-5-oxo-2-thiophen-2-yl-[1,4]thia...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibitory activity against rabbit lung Angiotensin I converting enzyme with 5 mM hippurylhistidylleucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NMJPubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50023296(2-(1-Carboxymethyl-2-oxo-7-phenyl-azepan-3-ylamino...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Concentration required for 50% inhibition of rabbit lung Angiotensin I converting enzyme with 5 mM hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75GWHPubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50023295(2-(4-Carboxymethyl-5-oxo-2-phenyl-[1,4]thiazepan-6...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Inhibitory activity against rabbit lung Angiotensin I converting enzyme with 5 mM hippurylhistidylleucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NMJPubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50023295(2-(4-Carboxymethyl-5-oxo-2-phenyl-[1,4]thiazepan-6...)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMAssay Description:Concentration required for 50% inhibition of rabbit lung Angiotensin I converting enzyme with 5 mM hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75GWHPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50441088(CHEMBL2430315)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as [14-C]AMG uptake preincubated for 10 mins followed by [14-C]AMG addition measured after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3GSMPubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50024713(2-(4-Carboxymethyl-5-oxo-2-thiophen-3-yl-[1,4]thia...)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibitory activity against rabbit lung Angiotensin I converting enzyme with 5 mM hippurylhistidylleucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NMJPubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50023300(2-(1-Carboxymethyl-2-oxo-6-phenyl-azepan-3-ylamino...)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Concentration required for 50% inhibition of rabbit lung Angiotensin I converting enzyme with 5 mM hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75GWHPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50446190(CHEMBL3109019)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50381537(CHEMBL2017954)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as [14-C]AMG uptake preincubated for 10 mins followed by [14-C]AMG addition measured after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3GSMPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50446187(CHEMBL3109020)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50011192((R)-1-[(S)-2-((S)-1-Carboxy-3-phenyl-propylamino)-...)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Inhibitory activity against rabbit lung Angiotensin I converting enzyme with 5 mM hippurylhistidylleucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NMJPubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50367254(ENALAPRILAT)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Concentration required for 50% inhibition of rabbit lung Angiotensin I converting enzyme with 5 mM hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75GWHPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50441082(CHEMBL2430319)copy SMILEScopy InChI
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as [14-C]AMG uptake preincubated for 10 mins followed by [14-C]AMG addition measured after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3GSMPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50441082(CHEMBL2430319)copy SMILEScopy InChI
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50438466(CHEMBL2414619)copy SMILEScopy InChI
Affinity DataIC50: 7.30nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as reduction of [14C]alpha-methyl-D-glucopyranoside uptake after 120 mins by liquid scinti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9DHVPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50446184(CHEMBL3109014)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50023302(2-(1-Carboxymethyl-2-oxo-7-phenyl-azepan-3-ylamino...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Concentration required for 50% inhibition of rabbit lung Angiotensin I converting enzyme with 5 mM hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75GWHPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50446189(CHEMBL3109018)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50446186(CHEMBL3109016)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of human SGLT1-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Sankyo Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50366241(CHEMBL297624 | L-652731)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibiting Platelet activating factor receptor by radioreceptor binding assay using rabbit platelets and [3H]-PAFMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3T06PubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50446182(CHEMBL3109012)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Sankyo Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50055488(CHEMBL148491 | Carbonic acid methyl ester (E)-(1R,...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibiting Platelet activating factor receptor by radioreceptor binding assay using rabbit platelets and [3H]-PAFMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3T06PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Sankyo Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50055491((E)-(1R,2R,3R,5R,12S,13R,16S)-16-(Isoxazol-3-yloxy...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibiting Platelet activating factor receptor by radioreceptor binding assay using rabbit platelets and [3H]-PAFMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3T06PubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50023303(2-(4-Carboxymethyl-5-oxo-2-phenyl-[1,4]thiazepan-6...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibitory activity against rabbit lung Angiotensin I converting enzyme with 5 mM hippurylhistidylleucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NMJPubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50023303(2-(4-Carboxymethyl-5-oxo-2-phenyl-[1,4]thiazepan-6...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Concentration required for 50% inhibition of rabbit lung Angiotensin I converting enzyme with 5 mM hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75GWHPubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Sankyo Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50055482((E)-(1R,3S,5R,12S,13R,16S)-16-(Isoxazol-3-yloxymet...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibiting Platelet activating factor receptor by radioreceptor binding assay using rabbit platelets and [3H]-PAFMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3T06PubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50024712(2-(4-Carboxymethyl-5-oxo-2-thiophen-2-yl-[1,4]thia...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibitory activity against rabbit lung Angiotensin I converting enzyme with 5 mM hippurylhistidylleucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NMJPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50441083(CHEMBL2430321)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of human SGLT2 expressed in CHOK cells assessed as [14-C]AMG uptake preincubated for 10 mins followed by [14-C]AMG addition measured after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3GSMPubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd

Curated by ChEMBL
LigandPNGBDBM50430288(CHEMBL2333435)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q1ZK9PubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50023301(2-(4-Carboxymethyl-5-oxo-3-phenyl-[1,4]thiazepan-6...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Concentration required for 50% inhibition of rabbit lung Angiotensin I converting enzyme with 5 mM hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2S75GWHPubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50023301(2-(4-Carboxymethyl-5-oxo-3-phenyl-[1,4]thiazepan-6...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Inhibitory activity against rabbit lung Angiotensin I converting enzyme with 5 mM hippurylhistidylleucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NMJPubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Sankyo Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50055479(Acetic acid (E)-(1R,2R,3R,5R,12S,13R,16S)-2-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibiting Platelet activating factor receptor by radioreceptor binding assay using rabbit platelets and [3H]-PAFMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3T06PubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Sankyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50024711(2-(4-Carboxymethyl-5-oxo-2-thiophen-3-yl-[1,4]thia...)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:Inhibitory activity against rabbit lung Angiotensin I converting enzyme with 5 mM hippurylhistidylleucine as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NMJPubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL
LigandPNGBDBM50446183(CHEMBL3109013)copy SMILEScopy InChI
Affinity DataIC50: 93nMAssay Description:Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 12...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24J0GM7PubMed
TargetPlatelet-activating factor receptor(Cavia porcellus)
Sankyo Co. Ltd

Curated by ChEMBL
LigandPNGBDBM50055489((E)-(1R,3S,5R,12S,13R,16S)-5,9,12,13-Tetramethyl-2...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibiting Platelet activating factor receptor by radioreceptor binding assay using rabbit platelets and [3H]-PAFMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FF3T06PubMed
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