Compile Data Set for Download or QSAR
Found 129 with Last Name = 'nara' and Initial = 'y'
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122654(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 0.0600nMAssay Description:Tested for inhibition of arachidonic acid(AA) release from CHO cells in HumanMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122652(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 0.0700nMAssay Description:Tested for inhibition of arachidonic acid(AA) release from CHO cells in HumanMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122652(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50409694(CHEMBL2092994)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122654(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50067485(3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122660(1-{4-[5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difl...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122667(1-{4-[5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difl...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122659(CHEMBL20511 | N-{4-[5-[(Benzyl-methyl-amino)-methy...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122656(CHEMBL280365 | N-{4-[5-[(Benzyl-methyl-amino)-meth...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122652(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Tested for antagonist concentration required to inhibit specific binding of [125I]leuprorelin to Leutinizing releasing hormone receptor in monkey (ch...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122657(CHEMBL21126 | N-{4-[5-[(Benzyl-methyl-amino)-methy...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122671(1-{4-[5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difl...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122674(CHEMBL280213 | N-{4-[5-[(Benzyl-methyl-amino)-meth...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122661(1-{4-[5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difl...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122654(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Tested for antagonist concentration required to inhibit specific binding of [125I]leuprorelin to LHRH receptor in monkey (chinese hamster ovary (CHO)...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50067485(3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of LHRH-stimulated arachidonic acid (AA) release from CHO cells expressing human Leutinizing releasing hormone receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122655(CHEMBL280212 | N-(4-(1-(2,6-difluorobenzyl)-5-((be...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122653(6-(4-Amino-phenyl)-5-[(benzyl-methyl-amino)-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50067485(3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Tested for antagonist concentration required to inhibit specific binding of [125I]leuprorelin to monkey Leutinizing releasing hormone receptor in clo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50517589(CHEMBL4100286)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Displacement of BODIPY-labeled-5-((2Z)-2-((1-(difluoroboryl)-3,5-dimethyl-1H-pyrrol-2-yl)-methylene)-2H-pyrrol-5-yl)-N-(2-((3,5-difluoro-4-(trimethyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VMHPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122657(CHEMBL21126 | N-{4-[5-[(Benzyl-methyl-amino)-methy...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Tested for inhibition of arachidonic acid(AA) release from CHO cells in HumanMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50517588(CHEMBL4446140)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Displacement of BODIPY-labeled-5-((2Z)-2-((1-(difluoroboryl)-3,5-dimethyl-1H-pyrrol-2-yl)-methylene)-2H-pyrrol-5-yl)-N-(2-((3,5-difluoro-4-(trimethyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VMHPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122652(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Tested for inhibition of arachidonic acid(AA) release from CHO cells in MonkeyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetIntegrase(Human immunodeficiency virus 1)
K.L.E.S. College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50183273((S)-6-(3-chloro-2-fluorobenzyl)-1-(1-hydroxy-3-met...)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P9255PubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50517591(CHEMBL4448684)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMAssay Description:Displacement of BODIPY-labeled-5-((2Z)-2-((1-(difluoroboryl)-3,5-dimethyl-1H-pyrrol-2-yl)-methylene)-2H-pyrrol-5-yl)-N-(2-((3,5-difluoro-4-(trimethyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VMHPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122657(CHEMBL21126 | N-{4-[5-[(Benzyl-methyl-amino)-methy...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Tested for antagonist concentration required to inhibit specific binding of [125I]leuprorelin to Leutinizing releasing hormone receptor in monkey (ch...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122654(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Tested for inhibition of arachidonic acid(AA) release from CHO cells in MonkeyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50517594(CHEMBL4543504)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Displacement of BODIPY-labeled-5-((2Z)-2-((1-(difluoroboryl)-3,5-dimethyl-1H-pyrrol-2-yl)-methylene)-2H-pyrrol-5-yl)-N-(2-((3,5-difluoro-4-(trimethyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VMHPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50517593(CHEMBL4446549)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Displacement of BODIPY-labeled-5-((2Z)-2-((1-(difluoroboryl)-3,5-dimethyl-1H-pyrrol-2-yl)-methylene)-2H-pyrrol-5-yl)-N-(2-((3,5-difluoro-4-(trimethyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VMHPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122669(CHEMBL21185 | N-{4-[5-[(Benzyl-methyl-amino)-methy...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122663(5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50517592(CHEMBL4464336)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Displacement of BODIPY-labeled-5-((2Z)-2-((1-(difluoroboryl)-3,5-dimethyl-1H-pyrrol-2-yl)-methylene)-2H-pyrrol-5-yl)-N-(2-((3,5-difluoro-4-(trimethyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VMHPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122658(5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122670(5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50517586(CHEMBL4562603)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Displacement of BODIPY-labeled-5-((2Z)-2-((1-(difluoroboryl)-3,5-dimethyl-1H-pyrrol-2-yl)-methylene)-2H-pyrrol-5-yl)-N-(2-((3,5-difluoro-4-(trimethyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122673(5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50067485(3-[(Benzyl-methyl-amino)-methyl]-7-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Tested for antagonist concentration required to inhibit specific binding of [125I]leuprorelin to Leutinizing releasing hormone receptor in rat anteri...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122666(5-[(Benzyl-methyl-amino)-methyl]-3-(2-chloro-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122665(5-[(Benzyl-methyl-amino)-methyl]-3-(4-chloro-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122652(1-(4-(1-(2,6-difluorobenzyl)-5-((benzyl(methyl)ami...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Tested for antagonist concentration required to inhibit specific binding of [125I]leuprorelin to Leutinizing releasing hormone receptor in rat anteri...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122662(5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetIntegrase(Human immunodeficiency virus 1)
K.L.E.S. College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM107681((2Z)-4-[3,5-bis(benzyloxy)phenyl]-2-hydroxy-4- oxo...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of HIV1 integrase-mediated 3'-end processing activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P9255PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122672(5-[(Benzyl-methyl-amino)-methyl]-3-(3-chloro-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50517590(CHEMBL4454637)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:Displacement of BODIPY-labeled-5-((2Z)-2-((1-(difluoroboryl)-3,5-dimethyl-1H-pyrrol-2-yl)-methylene)-2H-pyrrol-5-yl)-N-(2-((3,5-difluoro-4-(trimethyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DF6VMHPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122657(CHEMBL21126 | N-{4-[5-[(Benzyl-methyl-amino)-methy...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Tested for inhibition of arachidonic acid(AA) release from CHO cells in MonkeyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122668(3-Benzyl-5-[(benzyl-methyl-amino)-methyl]-1-(2,6-d...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50459230(CHEMBL4215472)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1VC9PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122675(5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-b...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50122664(5-[(Benzyl-methyl-amino)-methyl]-3-cyclohexyl-1-(2...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Antagonist concentration required to inhibit specific binding of [125I]leuprorelin to human luteinizing releasing hormone receptor in cloned chinese ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9BTRPubMed
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