Compile Data Set for Download or QSAR
Found 54 with Last Name = 'shibouta' and Initial = 'y'
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50406422(CHEMBL2115381)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Reduction of lipid peroxide formed in rat brain homogenates.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010968(3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyc...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010960((E)-7-Phenyl-7-pyridin-3-yl-hept-6-enoic acid | 7-...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010949(8-Pyridin-3-yl-8-(2,4,5-trimethyl-3,6-dioxo-cycloh...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50006803(2,3,5-Trimethyl-6-pyridin-3-ylmethyl-[1,4]benzoqui...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010970(7-Pyridin-3-yl-7-(2,4,5-trimethyl-3,6-dioxo-cycloh...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010958(2,3,5-Trimethyl-6-(1-pyridin-3-yl-heptyl)-[1,4]ben...)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010961(2-Methyl-3-pyridin-3-ylmethyl-[1,4]naphthoquinone ...)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010945(Acetic acid 6-pyridin-3-yl-6-(2,4,5-trimethyl-3,6-...)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010947(6-Pyridin-3-yl-6-(2,4,5-trimethyl-3,6-dioxo-cycloh...)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50006811(2-(12-Hydroxy-5,10-dodecadiynyl)-3,5,6-trimethyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010952(2-(6-Hydroxy-1-pyridin-3-yl-hexyl)-3,5,6-trimethyl...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010944(2-(5-Hydroxy-1-pyridin-3-yl-pentyl)-3,5,6-trimethy...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Reduction of lipid peroxide formed in rat brain homogenates.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010966(7-Pyridin-3-yl-7-(2,4,5-trimethyl-3,6-dioxo-cycloh...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010951(Acetic acid 5-pyridin-3-yl-5-(2,4,5-trimethyl-3,6-...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50006803(2,3,5-Trimethyl-6-pyridin-3-ylmethyl-[1,4]benzoqui...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010961(2-Methyl-3-pyridin-3-ylmethyl-[1,4]naphthoquinone ...)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010950(3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyc...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010957(2-Methyl-3-{2-[pyridin-3-yl-(2,4,5-trimethyl-3,6-d...)copy SMILEScopy InChI
Affinity DataIC50: 520nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010958(2,3,5-Trimethyl-6-(1-pyridin-3-yl-heptyl)-[1,4]ben...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Reduction of lipid peroxide formed in rat brain homogenates.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010946(2,3,5-Trimethyl-6-(1-pyridin-3-yl-hept-1-enyl)-[1,...)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:Reduction of lipid peroxide formed in rat brain homogenates.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010953(2,3,5-Trimethyl-6-(1-pyridin-3-yl-propyl)-[1,4]ben...)copy SMILEScopy InChI
Affinity DataIC50: 660nMAssay Description:Reduction of lipid peroxide formed in rat brain homogenates.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50006803(2,3,5-Trimethyl-6-pyridin-3-ylmethyl-[1,4]benzoqui...)copy SMILEScopy InChI
Affinity DataIC50: 680nMAssay Description:Reduction of lipid peroxide formed in rat brain homogenates.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010954(2,3,5-Trimethyl-6-(1-pyridin-3-yl-ethyl)-[1,4]benz...)copy SMILEScopy InChI
Affinity DataIC50: 720nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010954(2,3,5-Trimethyl-6-(1-pyridin-3-yl-ethyl)-[1,4]benz...)copy SMILEScopy InChI
Affinity DataIC50: 720nMAssay Description:Reduction of lipid peroxide formed in rat brain homogenates.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010951(Acetic acid 5-pyridin-3-yl-5-(2,4,5-trimethyl-3,6-...)copy SMILEScopy InChI
Affinity DataIC50: 820nMAssay Description:Reduction of lipid peroxide formed in rat brain homogenates.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010952(2-(6-Hydroxy-1-pyridin-3-yl-hexyl)-3,5,6-trimethyl...)copy SMILEScopy InChI
Affinity DataIC50: 820nMAssay Description:Reduction of lipid peroxide formed in rat brain homogenates.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010956(2,3,5-Trimethyl-6-(1-pyridin-3-yl-pentyl)-[1,4]ben...)copy SMILEScopy InChI
Affinity DataIC50: 830nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010953(2,3,5-Trimethyl-6-(1-pyridin-3-yl-propyl)-[1,4]ben...)copy SMILEScopy InChI
Affinity DataIC50: 830nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010956(2,3,5-Trimethyl-6-(1-pyridin-3-yl-pentyl)-[1,4]ben...)copy SMILEScopy InChI
Affinity DataIC50: 840nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010953(2,3,5-Trimethyl-6-(1-pyridin-3-yl-propyl)-[1,4]ben...)copy SMILEScopy InChI
Affinity DataIC50: 840nMAssay Description:Reduction of lipid peroxide formed in rat brain homogenates.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010948(2,3,5-Trimethyl-6-(phenyl-pyridin-3-yl-methyl)-[1,...)copy SMILEScopy InChI
Affinity DataIC50: 860nMAssay Description:Reduction of lipid peroxide formed in rat brain homogenates.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010946(2,3,5-Trimethyl-6-(1-pyridin-3-yl-hept-1-enyl)-[1,...)copy SMILEScopy InChI
Affinity DataIC50: 860nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010945(Acetic acid 6-pyridin-3-yl-6-(2,4,5-trimethyl-3,6-...)copy SMILEScopy InChI
Affinity DataIC50: 870nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010952(2-(6-Hydroxy-1-pyridin-3-yl-hexyl)-3,5,6-trimethyl...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010944(2-(5-Hydroxy-1-pyridin-3-yl-pentyl)-3,5,6-trimethy...)copy SMILEScopy InChI
Affinity DataIC50: 920nMAssay Description:Reduction of lipid peroxide formed in rat brain homogenates.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010945(Acetic acid 6-pyridin-3-yl-6-(2,4,5-trimethyl-3,6-...)copy SMILEScopy InChI
Affinity DataIC50: 950nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010959(3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyc...)copy SMILEScopy InChI
Affinity DataIC50: 970nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010949(8-Pyridin-3-yl-8-(2,4,5-trimethyl-3,6-dioxo-cycloh...)copy SMILEScopy InChI
Affinity DataIC50: 990nMAssay Description:Reduction of lipid peroxide formed in rat brain homogenates.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010944(2-(5-Hydroxy-1-pyridin-3-yl-pentyl)-3,5,6-trimethy...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010951(Acetic acid 5-pyridin-3-yl-5-(2,4,5-trimethyl-3,6-...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010958(2,3,5-Trimethyl-6-(1-pyridin-3-yl-heptyl)-[1,4]ben...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of horse thromboxane A2 synthase evaluated as molar concentration required to reduce thromboxane B2 formed after incubating PGH-2 with pla...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010959(3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyc...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010964(2,3-Dimethoxy-5-methyl-6-pyridin-3-ylmethyl-[1,4]b...)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+3nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010949(8-Pyridin-3-yl-8-(2,4,5-trimethyl-3,6-dioxo-cycloh...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010966(7-Pyridin-3-yl-7-(2,4,5-trimethyl-3,6-dioxo-cycloh...)copy SMILEScopy InChI
Affinity DataIC50: 7.20E+3nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010965(3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyc...)copy SMILEScopy InChI
Affinity DataIC50: 8.70E+3nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010950(3-(2,5-Dimethyl-3,6-dioxo-4-pyridin-3-ylmethyl-cyc...)copy SMILEScopy InChI
Affinity DataIC50: 8.80E+3nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010970(7-Pyridin-3-yl-7-(2,4,5-trimethyl-3,6-dioxo-cycloh...)copy SMILEScopy InChI
Affinity DataIC50: 9.30E+3nMAssay Description:The concentration required to reduce by 50% the amount of LTB4 formed by RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Takeda Chemical Industries, Ltd.

Curated by ChEMBL
LigandPNGBDBM50010954(2,3,5-Trimethyl-6-(1-pyridin-3-yl-ethyl)-[1,4]benz...)copy SMILEScopy InChI
Affinity DataIC50: 9.50E+3nMAssay Description:Reduction of lipid peroxide formed in rat brain homogenates.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SN07X9PubMed
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