Compile Data Set for Download or QSAR
Found 378 with Last Name = 'takaoka' and Initial = 'y'
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM10882(6-ethoxy-1,3-benzothiazole-2-sulfonamide | CHEMBL1...)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Inhibition of carbonic anhydrase 1 in human RBC cells by SDS-PAGE/fluorescence gel imagingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37WHVPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM12414(CHEMBL27601 | benzenesulfonamide | hCA inhibitor, ...)copy SMILEScopy InChI
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of carbonic anhydrase 1 in human RBC cells by SDS-PAGE/fluorescence gel imagingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37WHVPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM4703(4-carboxybenzenesulfonamide 1 | 4-sulfamoylbenzoic...)copy SMILEScopy InChI
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of carbonic anhydrase 1 in human RBC cells by SDS-PAGE/fluorescence gel imagingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W37WHVPubMed
TargetLysophosphatidic acid receptor 1(Homo sapiens (Human))
ONO Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50285779(CHEMBL4165205)copy SMILEScopy InChI
Affinity DataIC50: 0.160nMAssay Description:Antagonist activity at recombinant human LPA1 expressed in CHO cell membranes pretreated for 24 hrs prior to Fura-2-AM dye addition for 1 hr followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1V8ZPubMed
TargetLysophosphatidic acid receptor 1(Homo sapiens (Human))
ONO Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50285779(CHEMBL4165205)copy SMILEScopy InChI
Affinity DataIC50: 0.190nMAssay Description:Antagonist activity at recombinant human LPA1 expressed in CHO cell membranes pretreated for 24 hrs prior to Fura-2-AM dye addition for 1 hr followed...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1V8ZPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50198936((R)-1-butyl-3-((R)-cyclohexyl-hydroxy-methyl)-9-(4...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Displacement of [125I]MIP1-alpha from human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GCMPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50377933(CHEMBL1744354)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KGNPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50242595(CHEMBL487860 | N-[2-({2-[(2S,4S)-2-Cyano-4-fluorop...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KGNPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50362277(CHEMBL1939601)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27VQTPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50242577(6-{[2-({2-[(2S,4S)-2-Cyano-4-fluoropyrrolidin-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KGNPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50242517((2S,4S)-1-(N-Cyclopentylglycyl)-4-fluoropyrrolidin...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KGNPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50362259(CHEMBL1939570)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27VQTPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50242576((2S,4S)-1-(N-{2-[(5-Chloropyridin-2-yl)amino]ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KGNPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50242575((2S,4S)-4-Fluoro-1-{N-[2-(pyridin-2-ylamino)ethyl]...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KGNPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50242593(CHEMBL488036 | N-[2-({2-[(2S,4S)-2-Cyano-4-fluorop...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KGNPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50242495((2S,4S)-1-[N-(tert-Butyl)glycyl]-4-fluoropyrrolidi...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KGNPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50242516((2S,4S)-1-(N-Cyclobutylglycyl)-4-fluoropyrrolidine...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KGNPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50242530((2S,4S)-1-(N-2-Adamantylglycyl)-4-fluoropyrrolidin...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KGNPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50242531((2S,4S)-4-Fluoro-1-[N-(3-hydroxy-1-adamantyl)-glyc...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KGNPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50242519((2S,4S)-1-(N-Cyclooctylglycyl)-4-fluoropyrrolidine...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KGNPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50242518((2S,4S)-4-Fluoro-1-{N-[1-(hydroxymethyl)cyclopenty...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KGNPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50362291(CHEMBL1939590)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27VQTPubMed
TargetLysophosphatidic acid receptor 1(Homo sapiens (Human))
ONO Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50195700(CHEMBL3975893)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X350FRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50198939((R)-1-butyl-3-((R)-1-hydroxy-2-methyl-propyl)-9-(4...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Displacement of [125I]MIP1-alpha from human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GCMPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50362260(CHEMBL1939571)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27VQTPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50362269(CHEMBL1939593)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27VQTPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50242529((2S,4S)-1-(N-1-Adamantylglycyl)-4-fluoropyrrolidin...)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KGNPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50362279(CHEMBL1939603)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27VQTPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50362286(CHEMBL1939585)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27VQTPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50362270(CHEMBL1939594)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27VQTPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50242579(CHEMBL488418 | N-[2-({2-[(2S,4S)-2-Cyano-4-fluorop...)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KGNPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50362284(CHEMBL1939583)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27VQTPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50242513((2S,4S)-4-Fluoro-1-[N-(2-hydroxy-1,1-dimethylethyl...)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KGNPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50362273(CHEMBL1939597)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27VQTPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50362271(CHEMBL1939595)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27VQTPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50242533((2S,4S)-4-Fluoro-1-[N-(5-hydroxy-2-adamantyl)-glyc...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KGNPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50362280(CHEMBL1939592)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27VQTPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50242580(CHEMBL488419 | N-[2-({2-[(2S,4S)-2-Cyano-4-fluorop...)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KGNPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50336345(4-(4-(((R)-1-butyl-3-((R)-cyclohexyl(hydroxy)methy...)copy SMILEScopy InChI
Affinity DataIC50: 5.62nMAssay Description:Antagonist activity at human CCR5 expressed in HOS cells assessed as inhibition of cell fusion with HIV gp120 expressing HEK293 cells by LTR lucifera...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JP0PubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50362288(CHEMBL1939587)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27VQTPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50242594(CHEMBL519585 | N-[2-({2-[(2S,4S)-2-Cyano-4-fluorop...)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KGNPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50336345(4-(4-(((R)-1-butyl-3-((R)-cyclohexyl(hydroxy)methy...)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Antagonist activity at human CCR5 expressed in CHO cells assessed as inhibition of MIP-1alpha-induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G5QPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50242596(CHEMBL487861 | N-[2-({2-[(2S,4S)-2-Cyano-4-fluorop...)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KGNPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50336345(4-(4-(((R)-1-butyl-3-((R)-cyclohexyl(hydroxy)methy...)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Displacement of MIP-1alpha from human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70G5QPubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50362289(CHEMBL1939588)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B27VQTPubMed
TargetLysophosphatidic acid receptor 1(Homo sapiens (Human))
ONO Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50195694(CHEMBL3976876)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Antagonist activity at human LPA1 receptor expressed in CHO cells assessed as reduction in LPA-induced intracellular Ca2+ concentration pretreated wi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X350FRPubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Ono Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50190516((RS)-1-butyl-3-(cyclohexylmethyl)-9-(4-phenoxybenz...)copy SMILEScopy InChI
Affinity DataIC50: 6.10nMAssay Description:Displacement of [125I]MIP1-alpha from human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GCMPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50242476(CHEMBL471088 | N-[2-({2-[(2S,4S)-2-Cyano-4-fluorop...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KGNPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM11113(6-{[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KGNPubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50242475(CHEMBL470893 | N-[2-({2-[(2S,4S)-2-Cyano-4-fluorop...)copy SMILEScopy InChI
Affinity DataIC50: 7.30nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1KGNPubMed
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