TargetProtein kinase C theta type(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd
Curated by ChEMBL
Takeda Pharmaceutical Company, Ltd
Curated by ChEMBL
Affinity DataIC50: 0.0860nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus expression system using fluorescein-PKC as substrate preincub...More data for this Ligand-Target Pair
TargetProtein kinase C theta type(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd
Curated by ChEMBL
Takeda Pharmaceutical Company, Ltd
Curated by ChEMBL
Affinity DataIC50: 0.180nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus expression system using fluorescein-PKC as substrate preincub...More data for this Ligand-Target Pair
TargetProtein kinase C theta type(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd
Curated by ChEMBL
Takeda Pharmaceutical Company, Ltd
Curated by ChEMBL
Affinity DataIC50: 0.870nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus expression system using fluorescein-PKC as substrate preincub...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of C-terminal biotin-labelled BCoR (Arg498 to 514Pro residues) binding to recombinant FLAG-tagged BCL6 BTB (5 to 129 residues) (unknown or...More data for this Ligand-Target Pair
TargetProtein kinase C theta type(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd
Curated by ChEMBL
Takeda Pharmaceutical Company, Ltd
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus expression system using fluorescein-PKC as substrate preincub...More data for this Ligand-Target Pair
TargetProtein kinase C theta type(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd
Curated by ChEMBL
Takeda Pharmaceutical Company, Ltd
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus expression system using fluorescein-PKC as substrate preincub...More data for this Ligand-Target Pair
TargetProtein kinase C theta type(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd
Curated by ChEMBL
Takeda Pharmaceutical Company, Ltd
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus expression system using fluorescein-PKC as substrate preincub...More data for this Ligand-Target Pair
TargetProtein kinase C theta type(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd
Curated by ChEMBL
Takeda Pharmaceutical Company, Ltd
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus expression system using fluorescein-PKC as substrate preincub...More data for this Ligand-Target Pair
TargetProtein kinase C theta type(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd
Curated by ChEMBL
Takeda Pharmaceutical Company, Ltd
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus expression system using fluorescein-PKC as substrate preincub...More data for this Ligand-Target Pair
TargetProtein kinase C theta type(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd
Curated by ChEMBL
Takeda Pharmaceutical Company, Ltd
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus expression system using fluorescein-PKC as substrate preincub...More data for this Ligand-Target Pair
TargetProtein kinase C theta type(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd
Curated by ChEMBL
Takeda Pharmaceutical Company, Ltd
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus expression system using fluorescein-PKC as substrate preincub...More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Compounds were tested employing a microtubule gliding assay, a standard biochemical assay for motor proteins. The first set of studies focused on hum...More data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Compounds were tested employing a microtubule gliding assay, a standard biochemical assay for motor proteins. The first set of studies focused on hum...More data for this Ligand-Target Pair
Affinity DataIC50: 710nMAssay Description:Compounds were tested employing a microtubule gliding assay, a standard biochemical assay for motor proteins. The first set of studies focused on hum...More data for this Ligand-Target Pair
Affinity DataIC50: 730nMAssay Description:Compounds were tested employing a microtubule gliding assay, a standard biochemical assay for motor proteins. The first set of studies focused on hum...More data for this Ligand-Target Pair
TargetProtein kinase C theta type(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd
Curated by ChEMBL
Takeda Pharmaceutical Company, Ltd
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus expression system using fluorescein-PKC as substrate preincub...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Compounds were tested employing a microtubule gliding assay, a standard biochemical assay for motor proteins. The first set of studies focused on hum...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMAssay Description:Compounds were tested employing a microtubule gliding assay, a standard biochemical assay for motor proteins. The first set of studies focused on hum...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 2.12E+5nMAssay Description:Inhibition of C-terminal biotin-labelled BCoR/wild-type BCL6 BTB domain (unknown origin) protein-protein interaction by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 250nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 670nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 270nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 34nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 970nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 140nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 180nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 29nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 26nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 160nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 62nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 74nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 840nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 83nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 150nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 150nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataKd: 5nMAssay Description:Binding affinity to human GPR40 expressed in CHO cells by LC-MS analysisMore data for this Ligand-Target Pair
Affinity DataKd: 12nMAssay Description:Binding affinity to human GPR40 expressed in CHO cells by LC-MS analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 410nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells incubated for 60 mins by FLIPR based Ca2+ mobilization assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.570nMAssay Description:Binding affinity to biotinylated BCL6 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.29E+5nMAssay Description:Binding affinity to recombinant RED-NHS labelled BCL6 BTB domain (1 to 129 residues) (unknown origin) after 10 mins by microscale thermophoresis meth...More data for this Ligand-Target Pair
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